Evidence: osteoarthritis / joint supplementation in dogs
Source: Europe PMC (Europe PubMed Central) REST search — first-hand peer-reviewed abstract records, pulled 2026-07-21. Query: (osteoarthritis OR "osteoarthritis") AND dog AND (glucosamine OR chondroitin OR "omega-3" OR supplement). The cluster returns 2605 records in Europe PMC; 6 representative studies are extracted below. Abstract text is verbatim from source; each study is traceable by PMID.
Studies
- PMID 41929275 (2026, Frontiers in veterinary science) — Protective effects of turmerosaccharides rich extract of <i>Curcuma longa</i> L. in osteoarthritic dogs.. <h4>Introduction</h4>Osteoarthritis (OA) is a progressive degenerative joint disease characterized by cartilage deterioration, leading to chronic pain and impaired immobility particularly in older dogs.<h4>Aim</h4>This s
- PMID 41630707 (2025, Open veterinary journal) — A multimodal approach to Canine Osteoarthritis management: A state-of-the-art.. Canine osteoarthritis (OA) is a prevalent, progressive, and debilitating joint disorder characterized by cartilage degradation, synovial inflammation, and subchondral bone remodeling.
- PMID 41635790 (2025, Frontiers in veterinary science) — Efficacy, pharmacokinetics and safety of liposomal synthetic cannabidiol injected subcutaneously in dogs: a randomized, blinded, placebo-controlled, crossover clinical trial.. <h4>Background</h4>Cannabidiol (CBD) has anti-nociceptive and anti-inflammatory characteristics, and was reported to provide analgesia in dogs with osteoarthritis.
- PMID 41183983 (2025, The Journal of veterinary medical science) — A review of the clinical efficacy and adverse effects of disease modifying osteoarthritic drugs (DMOADs) in dogs with special focus on glucosamine and pentosan polysulfate; do they work?. Osteoarthritis (OA) or degenerative joint disease (DJD) is a degenerative joint disease that progressively causes loss of joint function and is the most common and costly form of arthritis.
- PMID 40530040 (2025, Frontiers in veterinary science) — Efficacy of a joint supplement containing eggshell membrane among other ingredients to improve the mobility of dogs with osteoarthritis: a multicenter double-blind randomized placebo-controlled study.. The management of osteoarthritis (OA) in dogs is typically multimodal, including weight management, activity adjustment, joint supplements, and medical treatments when needed.
- PMID 41737916 (2025, Frontiers in veterinary science) — A randomized, double-blind, controlled study on the efficacy of an oral dietary supplement containing fish oil, ASU and phytotherapeutic extracts in canine osteoarthritis.. Osteoarthritis (OA) is a common musculoskeletal disorder in canines, characterized by discomfort, lameness, and reduced mobility.
Source text: pdf-raw/evidence/europepmc_joint_oa_2026-07-21.txt (Europe PMC first-hand abstracts, pulled 2026-07-21).