{"topic_id":"evidence_joint_oa","category":"evidence","context":"---\ntopic_id: evidence_joint_oa\ncategory: evidence\ntitle: \"Evidence cluster — osteoarthritis / joint supplements in dogs (peer-reviewed, Europe PMC)\"\nlang: en\nsource: \"Europe PMC (Europe PubMed Central) REST search, first-hand peer-reviewed abstracts, pulled 2026-07-21\"\nsource_file: pdf-raw/evidence/europepmc_joint_oa_2026-07-21.txt\ndate_parsed: 2026-07-21\ntokens_estimated: 415\nverification:\n  method: substring_match\n  claims: 30\n  passed: 30\n  date: 2026-07-21\nsource_document: \"Veterinary / medical evidence (guideline or study) — PMID 41929275\"\ncitation:\n  authority: \"Europe PMC\"\n  title: \"Evidence cluster — osteoarthritis / joint supplements in dogs (peer-reviewed, Europe PMC)\"\n  url: \"https://pubmed.ncbi.nlm.nih.gov/41929275/\"\n  retrieved: \"2026-07-21\"\n  ref: \"PMID 41929275\"\n  doc_type: \"official PDF\"\n  needs_review: false\nlicense: cc_by\nauthority_tier: T2\nauthority_tier_basis: \"T2:oa-repo\"\nauthority_tier_date: 2026-08-04\n---\n\n# Evidence: osteoarthritis / joint supplementation in dogs\n\nSource: Europe PMC (Europe PubMed Central) REST search — first-hand peer-reviewed abstract records, pulled 2026-07-21. Query: `(osteoarthritis OR \"osteoarthritis\") AND dog AND (glucosamine OR chondroitin OR \"omega-3\" OR supplement)`. The cluster returns **2605** records in Europe PMC; 6 representative studies are extracted below. Abstract text is verbatim from source; each study is traceable by PMID.\n\n## Studies\n- **PMID 41929275 (2026, Frontiers in veterinary science)** — Protective effects of turmerosaccharides rich extract of &lt;i&gt;Curcuma longa&lt;/i&gt; L. in osteoarthritic dogs.. <h4>Introduction</h4>Osteoarthritis (OA) is a progressive degenerative joint disease characterized by cartilage deterioration, leading to chronic pain and impaired immobility particularly in older dogs.<h4>Aim</h4>This s\n- **PMID 41630707 (2025, Open veterinary journal)** — A multimodal approach to Canine Osteoarthritis management: A state-of-the-art.. Canine osteoarthritis (OA) is a prevalent, progressive, and debilitating joint disorder characterized by cartilage degradation, synovial inflammation, and subchondral bone remodeling.\n- **PMID 41635790 (2025, Frontiers in veterinary science)** — Efficacy, pharmacokinetics and safety of liposomal synthetic cannabidiol injected subcutaneously in dogs: a randomized, blinded, placebo-controlled, crossover clinical trial.. <h4>Background</h4>Cannabidiol (CBD) has anti-nociceptive and anti-inflammatory characteristics, and was reported to provide analgesia in dogs with osteoarthritis.\n- **PMID 41183983 (2025, The Journal of veterinary medical science)** — A review of the clinical efficacy and adverse effects of disease modifying osteoarthritic drugs (DMOADs) in dogs with special focus on glucosamine and pentosan polysulfate; do they work?. Osteoarthritis (OA) or degenerative joint disease (DJD) is a degenerative joint disease that progressively causes loss of joint function and is the most common and costly form of arthritis.\n- **PMID 40530040 (2025, Frontiers in veterinary science)** — Efficacy of a joint supplement containing eggshell membrane among other ingredients to improve the mobility of dogs with osteoarthritis: a multicenter double-blind randomized placebo-controlled study.. The management of osteoarthritis (OA) in dogs is typically multimodal, including weight management, activity adjustment, joint supplements, and medical treatments when needed.\n- **PMID 41737916 (2025, Frontiers in veterinary science)** — A randomized, double-blind, controlled study on the efficacy of an oral dietary supplement containing fish oil, ASU and phytotherapeutic extracts in canine osteoarthritis.. Osteoarthritis (OA) is a common musculoskeletal disorder in canines, characterized by discomfort, lameness, and reduced mobility.\n\nSource text: `pdf-raw/evidence/europepmc_joint_oa_2026-07-21.txt` (Europe PMC first-hand abstracts, pulled 2026-07-21).\n\n## License & attribution\n\nSource abstracts / records are Open Access under Creative Commons. Each referenced\nstudy is reproduced with attribution under its specific CC license (CC BY / CC BY-NC /\nCC BY-NC-ND); the exact license variant for each reference is stated on its Europe PMC /\nPMC record. Original records:\n- https://pubmed.ncbi.nlm.nih.gov/40530040/\n- https://pubmed.ncbi.nlm.nih.gov/41183983/\n- https://pubmed.ncbi.nlm.nih.gov/41630707/\n- https://pubmed.ncbi.nlm.nih.gov/41635790/\n- https://pubmed.ncbi.nlm.nih.gov/41737916/\n- https://pubmed.ncbi.nlm.nih.gov/41929275/\n","sources":["Europe PMC — Evidence cluster — osteoarthritis / joint supplements in dogs (peer-reviewed, Europe PMC) (retrieved 2026-07-21)"],"source":{"authority":"Europe PMC","title":"Evidence cluster — osteoarthritis / joint supplements in dogs (peer-reviewed, Europe PMC)","url":"https://pubmed.ncbi.nlm.nih.gov/41929275/","retrieved":"2026-07-21","ref":"PMID 41929275","doc_type":"official PDF","source_document":"Veterinary / medical evidence (guideline or study) — PMID 41929275","verification_file":"pdf-raw/evidence/europepmc_joint_oa_2026-07-21.txt"},"source_document":"Veterinary / medical evidence (guideline or study) — PMID 41929275","source_file":"pdf-raw/evidence/europepmc_joint_oa_2026-07-21.txt","trust":{"authority_tier":"T2","fidelity":"verbatim","license":"cc_by","display_grade":"A"},"tokens_estimated":415,"generated_at":null,"tip":"Use /api/v1/topics to discover more topics. /api/v1/nutrient for precise single-point queries. /api/v1/cross_compare for 2-3 standard comparisons."}