Evidence: feline chronic gingivostomatitis (FCGS): management & treatment (peer-reviewed, Europe PMC)
Source: Europe PMC (Europe PubMed Central) REST search — first-hand peer-reviewed abstract records, pulled 2026-07-24. Query: ("feline chronic gingivostomatitis" OR "feline gingivostomatitis" OR FCGS) AND (treatment OR management OR therapy). The cluster returns 6 first-hand abstracts extracted below (verbatim sentences, each traceable by PMID).
Verified claims (verbatim, substring of saved source)
- PMID 42249348 — Background Feline chronic gingivostomatitis (FCGS) is a debilitating inflammatory condition characterized by severe caudal oral mucosal inflammation and frequently necessitates extensive dental extractions.
- PMID 42375508 — Introduction Feline chronic gingivostomatitis (FCGS) is a painful chronic disease with limited treatment options, especially in severe cases.
- PMID 42091972 — Feline chronic gingivostomatitis (FCGS) is a debilitating oral disease characterized by immune dysregulation and chronic inflammation.
- PMID 42326482 — Feline chronic gingivostomatitis (FCGS) is characterized by persistent oral inflammation, leading to severe pain, hyporexia, weight loss, and reduced well-being.
- PMID 41757710 — ObjectivesThe study primarily evaluated the long-term safety of intravenous, allogeneic uterine-derived mesenchymal stromal cells (UMSCs) for client-owned cats affected with refractory feline chronic gingivostomatitis (FCGS).
- PMID 42076735 — Background Feline chronic gingivostomatitis (FCGS) is refractory stomatitis in cats.
Studies (PMID / year / journal / title)
- PMID 42249348 (2026, BMC veterinary research) — Unilateral partial-mouth extraction achieves complete clinical remission in cats with unilateral caudal feline chronic gingivostomatitis: a case series.
- PMID 42375508 (2026, Frontiers in veterinary science) — Evaluating the safety and efficacy of equine peripheral blood-derived mesenchymal stem cells in feline chronic gingivostomatitis.
- PMID 42091972 (2026, Scientific reports) — Transcriptomic evidence of CD8⁺ T-cell exhaustion-like phenotype and mitochondrial impairment underlying immune dysregulation in feline chronic gingivostomatitis.
- PMID 42326482 (2026, Brazilian journal of veterinary medicine) — Comparison of simple and rapid collection methods for measuring salivary IL-6 and PGE<sub>2</sub> in cats with chronic gingivostomatitis: a pilot study.
- PMID 41757710 (2026, Journal of feline medicine and surgery) — Long-term field safety study evaluating allogeneic, uterine-derived mesenchymal stem cells for refractory feline chronic gingivostomatitis.
- PMID 42076735 (2026, Veterinary sciences) — Combination Therapeutic Effect of Antibacterial and Antiviral Agents on Feline Chronic Gingivostomatitis Nonbounded to Prior Tooth Extraction Confirmed by Physical Signs and Clinical Biomarkers.
Source text: pdf-raw/evidence/pubmed_evidence_feline_stomatitis_gingivostomatitis_2026-07-24.txt (Europe PMC first-hand abstracts, pulled 2026-07-24).