Horse — neurologic disease (EPM / ataxia / motor neuron) — dietary management (Europe PMC)

Horse — neurologic disease (EPM / ataxia / motor neuron) — dietary management (Europe PMC)

Source: Europe PMC REST search, query "(horse OR equine) AND (neurologic OR ataxia OR EPM OR "motor neuron") AND (diet OR nutrition OR "vitamin E" OR feeding)", 6021 hits (2026-07-22). 6 representative studies below (filtered for species + nutrition relevance).

1. PMID 42461371 — *[Paraphrased derived summary — non-Open-Access source.]* A 2026 Equine Veterinary Journal study examined altered liver and small-intestine gene expression in horses with equine neuroaxonal dystrophy/degenerative myeloencephalopathy (eNAD/EDM)—the second most common cause of spinal ataxia in US horses; the excerpt is cut off before the diet/vitamin-E findings.
2. PMID 40443203 — *[Paraphrased derived summary — non-Open-Access source.]* A 2025 review summarizes diseases of the nervous system of equids in Brazil, noting CNS disease was little characterized there until the 1980s and that several university diagnostic laboratories later developed; the excerpt is cut off before the specific diseases and dietary links.
3. PMID 38205913 — Measurement of 8-hydroxy-2'-deoxyguanosine in serum and cerebrospinal fluid of horses with neuroaxonal degeneration and other causes of proprioceptive ataxia. (Journal of veterinary internal medicine, 2024). Abstract (opening): Eight-hydroxy-2'-deoxyguanosine (8-OHdG), a biomarker of oxidative damage evaluated in human neurodegenerative disease, has potential to correlate with postmortem diagnosis of neur *[CC BY — Open Access, verbatim with attribution.]*
4. PMID 38095342 — Clinical and histopathological features in horses with neuroaxonal degeneration: 100 cases (2017-2021). (Journal of veterinary internal medicine, 2024). Abstract (opening): Adult horses with proprioceptive ataxia and behavior changes that have histologic lesions consistent with neurodegenerative disease have been increasingly recognized. Describe the *[CC BY — Open Access, verbatim with attribution.]*
5. PMID 41893540 — The Dark Side of Grasslands: Endophyte Toxicosis in Horses-Exposure Risks, Health Consequences, and Management. (Toxins, 2026). Abstract (opening): Grasslands are the cornerstone of horse feeding, used for grazing and to produce roughages and their products. However, improper grassland management hides several threats for equi *[CC BY — Open Access, verbatim with attribution.]*
6. PMID 41893656 — Gaps Between Awareness and Prevention of West Nile Virus Among Horse Owners in an Endemic Country: A Cross-Sectional Study from Romania. (Veterinary sciences, 2026). Abstract (opening): West Nile virus (WNV) circulates endemically in Romania, yet prevention of WNV infection in horses largely depends on owner-driven decisions that require accurate risk perception a *[CC BY — Open Access, verbatim with attribution.]*

Note: study selection and synthesis are left to the API consumer; this topic only surfaces primary sources with verbatim abstract openings.

Source text: pdf-raw/evidence/europepmc_evidence_equine_neurologic_diet_2026-07-22.txt (Europe PMC REST + PubMed efetch, 2026-07-22).

License & attribution

Mixed licensing per COPYRIGHT_POLICY §3: Open Access (CC BY / CC BY-NC / CC BY-NC-ND) studies are reproduced verbatim with attribution under their specific CC license; non-Open-Access studies are paraphrased as derived fact summaries (numbers and proper nouns preserved, sentences rewritten). Original records:

• https://pubmed.ncbi.nlm.nih.gov/38095342/
• https://pubmed.ncbi.nlm.nih.gov/38205913/
• https://pubmed.ncbi.nlm.nih.gov/40443203/
• https://pubmed.ncbi.nlm.nih.gov/41893540/
• https://pubmed.ncbi.nlm.nih.gov/41893656/
• https://pubmed.ncbi.nlm.nih.gov/42461371/