Evidence: equine gastric ulcer syndrome: prophylaxis & omeprazole (peer-reviewed, Europe PMC)
Source: Europe PMC (Europe PubMed Central) REST search — first-hand peer-reviewed abstract records, pulled 2026-07-24. Query: (equine gastric ulcer OR "gastric ulcer syndrome") AND (prophylaxis OR omeprazole OR prevention). The cluster returns 6 first-hand abstracts extracted below (verbatim sentences, each traceable by PMID).
Verified claims (verbatim, substring of saved source)
- PMID 42375980 — Background Equine gastric ulcer syndrome (EGUS) is the most common disease affecting the equine stomach.
- PMID 41470044 — Background The number of horses with equine squamous gastric disease (ESGD) and equine gastric glandular disease (EGGD) recurrence when pharmacological treatment is discontinued is high.
- PMID 42076700 — Equine Gastric Ulcer Syndrome is a highly prevalent condition, yet its clinical diagnosis remains challenging due to the nonspecific nature of many associated signs.
- PMID PPR1037834 — The term Equine Gastric Ulcer Syndrome (EGUS) has been used since 1999.
- PMID 41532453 — Background Current treatment options for equine gastric ulcer syndrome (EGUS), such as omeprazole-a proton pump inhibitor (PPI)-have notable limitations, including the need for administration on an empty stomach.
- PMID 41600665 — Equine Gastric Ulcer Syndrome (EGUS) is a worldwide disease described in different categories of animals.
Studies (PMID / year / journal / title)
- PMID 42375980 (2026, Open veterinary journal) — Heart rate variability in horses with naturally occurring gastric ulcers: Response to omeprazole and sucralfate treatment.
- PMID 41470044 (2025, Equine veterinary journal) — Evaluation of a nutraceutical for prevention of equine ulcer recurrence.
- PMID 42076700 (2026, Veterinary sciences) — Physical vs. Behavioral Clinical Signs in Horses with Squamous and Glandular Gastric Ulcers.
- PMID PPR1037834 (2025, ) — The Current Status of Equine Gastric Ulcer Syndrome in Horses - Focusing on Diagnosis, Treatment and Prevention
- PMID 41532453 (2026, Equine veterinary journal) — Vonoprazan pharmacokinetics and effects on gastric pH following administration to fed and fasted horses.
- PMID 41600665 (2025, Veterinary sciences) — Changes in Fitness Parameters in Ridden Trained Showjumping Horses After Healing of Gastric Ulcers: Preliminary Results.
Source text: pdf-raw/evidence/pubmed_evidence_equine_gastric_ulcer_prophylaxis_2026-07-24.txt (Europe PMC first-hand abstracts, pulled 2026-07-24).