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Evidence cluster — equine gastric ulcer syndrome: prophylaxis & omeprazole (peer-reviewed, Europe PMC)

evidence_equine_gastric_ulcer_prophylaxis

Evidence: equine gastric ulcer syndrome: prophylaxis & omeprazole (peer-reviewed, Europe PMC)

Source: Europe PMC (Europe PubMed Central) REST search — first-hand peer-reviewed abstract records, pulled 2026-07-24. Query: (equine gastric ulcer OR "gastric ulcer syndrome") AND (prophylaxis OR omeprazole OR prevention). The cluster returns 6 first-hand abstracts extracted below (verbatim sentences, each traceable by PMID).

Verified claims (verbatim, substring of saved source)

  • PMID 42375980 — *[Paraphrased derived summary — non-Open-Access source.]* A study background states equine gastric ulcer syndrome (EGUS) is the most common disease of the equine stomach. (Source excerpt truncated to the background sentence only.)
  • PMID 41470044 — *[Paraphrased derived summary — non-Open-Access source.]* A study background notes that recurrence of equine squamous gastric disease (ESGD) and equine gastric glandular disease (EGGD) is high once pharmacological treatment is stopped. (Source excerpt truncated to the background sentence only.)
  • PMID 42076700 — Equine Gastric Ulcer Syndrome is a highly prevalent condition, yet its clinical diagnosis remains challenging due to the nonspecific nature of many associated signs. *[CC BY — Open Access, verbatim with attribution.]*
  • PMID PPR1037834 — The term Equine Gastric Ulcer Syndrome (EGUS) has been used since 1999.
  • PMID 41532453 — *[Paraphrased derived summary — non-Open-Access source.]* A study background notes current EGUS treatments such as omeprazole (a proton-pump inhibitor) have limitations, including the requirement to administer on an empty stomach. (Source excerpt truncated to the background sentence only.)
  • PMID 41600665 — Equine Gastric Ulcer Syndrome (EGUS) is a worldwide disease described in different categories of animals. *[CC BY — Open Access, verbatim with attribution.]*

Studies (PMID / year / journal / title)

  • PMID 42375980 (2026, Open veterinary journal) — *[Paraphrased derived summary — non-Open-Access source.]* A study background states equine gastric ulcer syndrome (EGUS) is the most common disease of the equine stomach. (Source excerpt truncated to the background sentence only.)
  • PMID 41470044 (2025, Equine veterinary journal) — *[Paraphrased derived summary — non-Open-Access source.]* A study background notes that recurrence of equine squamous gastric disease (ESGD) and equine gastric glandular disease (EGGD) is high once pharmacological treatment is stopped. (Source excerpt truncated to the background sentence only.)
  • PMID 42076700 (2026, Veterinary sciences) — Physical vs. Behavioral Clinical Signs in Horses with Squamous and Glandular Gastric Ulcers. *[CC BY — Open Access, verbatim with attribution.]*
  • PMID PPR1037834 (2025, ) — The Current Status of Equine Gastric Ulcer Syndrome in Horses - Focusing on Diagnosis, Treatment and Prevention
  • PMID 41532453 (2026, Equine veterinary journal) — *[Paraphrased derived summary — non-Open-Access source.]* A study background notes current EGUS treatments such as omeprazole (a proton-pump inhibitor) have limitations, including the requirement to administer on an empty stomach. (Source excerpt truncated to the background sentence only.)
  • PMID 41600665 (2025, Veterinary sciences) — Changes in Fitness Parameters in Ridden Trained Showjumping Horses After Healing of Gastric Ulcers: Preliminary Results. *[CC BY — Open Access, verbatim with attribution.]*

Source text: pdf-raw/evidence/pubmed_evidence_equine_gastric_ulcer_prophylaxis_2026-07-24.txt (Europe PMC first-hand abstracts, pulled 2026-07-24).

License & attribution

Mixed licensing per COPYRIGHT_POLICY §3: Open Access (CC BY / CC BY-NC / CC BY-NC-ND) studies are reproduced verbatim with attribution under their specific CC license; non-Open-Access studies are paraphrased as derived fact summaries (numbers and proper nouns preserved, sentences rewritten). Original records:

  • https://pubmed.ncbi.nlm.nih.gov/41470044/
  • https://pubmed.ncbi.nlm.nih.gov/41532453/
  • https://pubmed.ncbi.nlm.nih.gov/41600665/
  • https://pubmed.ncbi.nlm.nih.gov/42076700/
  • https://pubmed.ncbi.nlm.nih.gov/42375980/

Sources

Evidence cluster — equine gastric ulcer syndrome: prophylaxis & omeprazole (peer-reviewed, Europe PMC)
Source document: Veterinary / medical evidence (guideline or study) — PMID 42375980
Europe PMCPMID 42375980retrieved 2026-07-24

Verification file: pdf-raw/evidence/pubmed_evidence_equine_gastric_ulcer_prophylaxis_2026-07-24.txt