{"topic_id":"evidence_equine_gastric_ulcer_prophylaxis","category":"evidence","context":"---\ntopic_id: evidence_equine_gastric_ulcer_prophylaxis\ncategory: evidence\ntitle: \"Evidence cluster — equine gastric ulcer syndrome: prophylaxis & omeprazole (peer-reviewed, Europe PMC)\"\nlang: en\nsource: \"Europe PMC (Europe PubMed Central) REST search, first-hand peer-reviewed abstracts, pulled 2026-07-24\"\nsource_file: pdf-raw/evidence/pubmed_evidence_equine_gastric_ulcer_prophylaxis_2026-07-24.txt\ndate_parsed: 2026-07-24\ntokens_estimated: 420\nverified: true\nverification:\n  method: substring_match\n  claims: 6\n  passed: 6\n  date: 2026-07-24\n---\n\n# Evidence: equine gastric ulcer syndrome: prophylaxis & omeprazole (peer-reviewed, Europe PMC)\n\nSource: Europe PMC (Europe PubMed Central) REST search — first-hand peer-reviewed abstract records, pulled 2026-07-24. Query: `(equine gastric ulcer OR \"gastric ulcer syndrome\") AND (prophylaxis OR omeprazole OR prevention)`. The cluster returns **6** first-hand abstracts extracted below (verbatim sentences, each traceable by PMID).\n\n## Verified claims (verbatim, substring of saved source)\n- **PMID 42375980** — Background Equine gastric ulcer syndrome (EGUS) is the most common disease affecting the equine stomach.\n- **PMID 41470044** — Background The number of horses with equine squamous gastric disease (ESGD) and equine gastric glandular disease (EGGD) recurrence when pharmacological treatment is discontinued is high.\n- **PMID 42076700** — Equine Gastric Ulcer Syndrome is a highly prevalent condition, yet its clinical diagnosis remains challenging due to the nonspecific nature of many associated signs.\n- **PMID PPR1037834** — The term Equine Gastric Ulcer Syndrome (EGUS) has been used since 1999.\n- **PMID 41532453** — Background Current treatment options for equine gastric ulcer syndrome (EGUS), such as omeprazole-a proton pump inhibitor (PPI)-have notable limitations, including the need for administration on an empty stomach.\n- **PMID 41600665** — Equine Gastric Ulcer Syndrome (EGUS) is a worldwide disease described in different categories of animals.\n\n## Studies (PMID / year / journal / title)\n- **PMID 42375980 (2026, Open veterinary journal)** — Heart rate variability in horses with naturally occurring gastric ulcers: Response to omeprazole and sucralfate treatment.\n- **PMID 41470044 (2025, Equine veterinary journal)** — Evaluation of a nutraceutical for prevention of equine ulcer recurrence.\n- **PMID 42076700 (2026, Veterinary sciences)** — Physical vs. Behavioral Clinical Signs in Horses with Squamous and Glandular Gastric Ulcers.\n- **PMID PPR1037834 (2025, )** — The Current Status of Equine Gastric Ulcer Syndrome in Horses - Focusing on Diagnosis, Treatment and Prevention\n- **PMID 41532453 (2026, Equine veterinary journal)** — Vonoprazan pharmacokinetics and effects on gastric pH following administration to fed and fasted horses.\n- **PMID 41600665 (2025, Veterinary sciences)** — Changes in Fitness Parameters in Ridden Trained Showjumping Horses After Healing of Gastric Ulcers: Preliminary Results.\n\nSource text: `pdf-raw/evidence/pubmed_evidence_equine_gastric_ulcer_prophylaxis_2026-07-24.txt` (Europe PMC first-hand abstracts, pulled 2026-07-24).\n","sources":[],"tokens_estimated":527,"generated_at":null,"tip":"Use /api/v1/topics to discover more topics. /api/v1/nutrient for precise single-point queries. /api/v1/cross_compare for 2-3 standard comparisons."}