evidence_canine_calcium_oxalate_urolith_diet
Source: first-hand peer-reviewed abstracts (Europe PMC / PubMed efetch), reproduced verbatim. Each claim below is a C1 substring of the cited source file.
Claims (C1 — verbatim substrings of source_file)
- PMID 41961373 — Serum and urine metabolomic profiling in Miniature Schnauzer dogs with and without calcium oxalate urolithiasis (Metabolomics, 2026). Abstract (opening): INTRODUCTION: Calcium oxalate (CaOx) urolithiasis is associated with metabolic disorders, including dyslipidemia. Improved understanding of underlying metabolic derangements is needed. *[CC BY — Open Access, verbatim with attribution.]*
- PMID 41897919 — Neutrophil Extracellular Traps Promote Urolithiasis Formation in Dogs: A Preliminary Study (Animals (Basel), 2026). Abstract (opening): Canine urolithiasis is a common and highly recurrent urinary tract disease, with struvite and calcium oxalate being the predominant stone types. Stone formation has traditionally been attributed to urinary physicochemical factors, including urine pH, mineral supersaturation, and urinary tract infection. *[CC BY — Open Access, verbatim with attribution.]*
- PMID 42414994 — *[Paraphrased derived summary — non-Open-Access source.]* A 2026 BMC Veterinary Research case report describes off-label use of the SGLT2 inhibitor dapagliflozin in a dog with recurrent calcium-oxalate urolithiasis. Calcium-oxalate stones are common and recurring in dogs, conventionally managed with dietary modification, thiazide diuretics, and potassium citrate; in human medicine dapagliflozin (used for diabetes and chronic kidney disease) has been shown to alter urinary parameters linked to stone formation (abstract opening only; outcome not retrievable from the non-Open-Access record).
- PMID 41742526 — Outcomes of medical dissolution for suspected struvite uroliths in dogs using a therapeutic multipurpose urinary diet and antimicrobial therapy (J Vet Intern Med, 2026). Abstract (opening): BACKGROUND: The consensus recommendation is to medically dissolve suspected struvite uroliths in dogs. However, more data is needed on outcomes for protocols using therapeutic multipurpose urinary foods formulated for both struvite urolith dissolution and calcium oxalate urolith prevention. *[CC BY — Open Access, verbatim with attribution.]*
- PMID 41001835 — In Vivo Radiographic Characteristics Associated With the Mineral Composition of Calcium Oxalate, Struvite, and Cystine Lower Urinary Tract Uroliths in Dogs (J Vet Intern Med, 2025). Abstract (opening): BACKGROUND: Identifying urolith mineral composition (UMC) is crucial for treatment and prevention; however, current data rely on macroscopic or ex vivo studies. *[CC BY — Open Access, verbatim with attribution.]*
- PMID 42154599 — Protocol for establishing an infrared spectral reference library for canine urolith analysis (STAR Protoc, 2026). Abstract (opening): Canine urolithiasis is a common, recurrent urinary disorder in dogs, posing significant clinical and economic burdens. Breed predispositions suggest genetic and metabolic influences. *[CC BY — Open Access, verbatim with attribution.]*
Source: pdf-raw/evidence/europepmc_canine_calcium_oxalate_urolith_diet_2026-07-22.txt
License & attribution
Mixed licensing per COPYRIGHT_POLICY §3: Open Access (CC BY / CC BY-NC / CC BY-NC-ND) studies are reproduced verbatim with attribution under their specific CC license; non-Open-Access studies are paraphrased as derived fact summaries (numbers and proper nouns preserved, sentences rewritten). Original records:
- https://pubmed.ncbi.nlm.nih.gov/41001835/
- https://pubmed.ncbi.nlm.nih.gov/41742526/
- https://pubmed.ncbi.nlm.nih.gov/41897919/
- https://pubmed.ncbi.nlm.nih.gov/41961373/
- https://pubmed.ncbi.nlm.nih.gov/42154599/
- https://pubmed.ncbi.nlm.nih.gov/42414994/