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EU EMA Veterinary Dermatology: Corticosteroid and Ectoparasiticide Products for Dogs and Cats

eu_ema_qd_dermatology_pet

eu-2026-approvals 260 tok en 2026-07-21

Overview

The ATCvet QD category covers dermatologicals. Within the EMA Union Product Database (medicines-output-medicines-report, dataset generated 20/07/2026), the QD-classified veterinary products include a topical corticosteroid for dogs and several ectoparasiticides (flea/tick products) classified under QP. This entry focuses on the QD dermatology and QD-adjacent topical ectoparasiticides relevant to pet species.

QD Dermatological Products

Pruban (resocortol butyrate) โ€” EMEA/V/C/000048

  • ATCvet code: QD07AC90
  • INN: Resocortol butyrate (INN: resocortol butyrate)
  • Active substance: resocortol butyrate
  • Species: Dogs
  • Status: Withdrawn
  • Pharmacotherapeutic group: Corticosteroids, dermatological preparations
  • Therapeutic indication: Treatment of acute localised moist dermatitis (hot spots) in dogs
  • Marketing authorisation holder: Intervet International BV

Ectoparasiticides for Dogs and Cats (QP โ€” Adjacent)

Although classified under QP (antiparasitic products), the following are topical insecticides directly relevant to dermatological health of pets:

Comfortis (spinosad) โ€” EMEA/V/C/002233

  • ATCvet code: QP53BX03
  • INN: Spinosad (INN: spinosad)
  • Active substance: spinosad
  • Species: Dogs;Cats
  • Status: Withdrawn
  • Pharmacotherapeutic group: Other ectoparasiticides for systemic use
  • Therapeutic indication: Treatment and prevention of flea infestations (*Ctenocephalides felis*). The preventive effect against re-infestations is maintained for 4 weeks.
  • Marketing authorisation holder: Elanco GmbH

Activyl Tick Plus (indoxacarb;permethrin) โ€” EMEA/V/C/002234

  • ATCvet code: QP53AC54
  • INN: Indoxacarb;Permethrin (INN: indoxacarb; permethrin)
  • Active substance: indoxacarb; permethrin
  • Species: Dogs
  • Status: Withdrawn
  • Pharmacotherapeutic group: Ectoparasiticides for topical use, incl. insecticides
  • Therapeutic indication: Treatment of flea infestations (*Ctenocephalides felis*); the product has persistent insecticidal efficacy for up to 4 weeks against ticks.
  • Marketing authorisation holder: Intervet International BV

ProMeris (metaflumizone) โ€” EMEA/V/C/000107

  • ATCvet code: QP53AX25
  • INN: Metaflumizone (INN: metaflumizone)
  • Active substance: metaflumizone
  • Species: Cats
  • Status: Withdrawn
  • Pharmacotherapeutic group: Ectoparasiticides for topical use, incl. insecticides
  • Therapeutic indication: Treatment and prevention of flea infestations (*Ctenocephalides canis* and *C. felis*) in cats.
  • Marketing authorisation holder: Pfizer Limited

ProMeris Duo (metaflumizone;amitraz) โ€” EMEA/V/C/000108

  • ATCvet code: QP53AD51
  • INN: Metaflumizone;Amitraz (INN: metaflumizone; amitraz)
  • Active substance: metaflumizone; amitraz
  • Species: Dogs
  • Status: Withdrawn
  • Pharmacotherapeutic group: Ectoparasiticides for topical use, incl. insecticides
  • Therapeutic indication: For the treatment and prevention of infestations by fleas (*Ctenocephalides canis* and *C. felis*), and ticks (*Ixodes ricinus*, *Dermacentor reticulatus*, *Rhipicephalus sanguineus*) in dogs.
  • Marketing authorisation holder: Pfizer Limited

Certifect (fipronil/amitraz/(S)-methoprene) โ€” EMEA/V/C/002002

  • ATCvet code: QP53AX65
  • INN: Fipronil / Amitraz / (S)-Methoprene (INN: fipronil; amitraz; (S)-methoprene)
  • Active substance: fipronil; amitraz; (S)-methoprene
  • Species: Dogs
  • Status: Withdrawn
  • Pharmacotherapeutic group: Ectoparasiticides for topical use, incl. insecticides
  • Therapeutic indication: Treatment and prevention of infestations in dogs by ticks (*Ixodes ricinus*, *Dermacentor reticulatus*, *Rhipicephalus sanguineus*) and fleas (*Ctenocephalides* spp.).
  • Marketing authorisation holder: Merial

Cheristin โ€” EMEA/V/C/004316

  • ATCvet code: QP53AX
  • Species: Cats
  • Status: Application withdrawn
  • Therapeutic indication: For the treatment and prevention of flea infestations (*Ctenocephalides felis*) on cats.
  • Marketing authorisation holder: Elanco Europe Ltd

Key Facts

  1. QD07AC90 = resocortol butyrate โ€” topical corticosteroid for acute localized moist dermatitis (hot spots) in dogs; MA holder Intervet International BV (EMEA/V/C/000048, Withdrawn).
  2. QP53BX03 = spinosad โ€” systemic oral flea adulticide for dogs and cats; UK/CETMART brand Comfortis; Withdrawn.
  3. QP53AC54 = indoxacarb + permethrin โ€” combination topical flea/tick product for dogs; Withdrawn.
  4. QP53AX65 = fipronil + amitraz + (S)-methoprene โ€” triple-action topical ectoparasiticide for dogs; Withdrawn.
  5. All pet topical ectoparasiticides in the EMA database carry Withdrawn or Application withdrawn status, indicating these products are no longer marketed under their EMA MA numbers.

Source: EMA medicines-output-medicines-report_en.xlsx, dataset generated 20/07/2026 - 18:00, accessed via https://www.ema.europa.eu/en/medicines/download-medicine-data.

Sources

  • ema-medicines-report.xlsx