{"topic_id":"eu_ema_qd_dermatology_pet","category":"eu-2026-approvals","context":"---\ntopic_id: eu_ema_qd_dermatology_pet\ncategory: eu-2026-approvals\ntitle: \"EU EMA Veterinary Dermatology: Corticosteroid and Ectoparasiticide Products for Dogs and Cats\"\nlang: en\nsource: \"ema-medicines-report.xlsx\"\ndate_parsed: \"2026-07-21\"\ntokens_estimated: 260\nverification:\n  method: substring_match\n  claims: 5\n  passed: 5\n  date: \"2026-07-21\"\n---\n\n## Overview\n\nThe ATCvet **QD** category covers dermatologicals. Within the EMA Union Product Database (medicines-output-medicines-report, dataset generated 20/07/2026), the QD-classified veterinary products include a topical corticosteroid for dogs and several ectoparasiticides (flea/tick products) classified under QP. This entry focuses on the QD dermatology and QD-adjacent topical ectoparasiticides relevant to pet species.\n\n## QD Dermatological Products\n\n### Pruban (resocortol butyrate) — EMEA/V/C/000048\n\n- **ATCvet code**: QD07AC90\n- **INN**: Resocortol butyrate (INN: resocortol butyrate)\n- **Active substance**: resocortol butyrate\n- **Species**: Dogs\n- **Status**: Withdrawn\n- **Pharmacotherapeutic group**: Corticosteroids, dermatological preparations\n- **Therapeutic indication**: Treatment of acute localised moist dermatitis (hot spots) in dogs\n- **Marketing authorisation holder**: Intervet International BV\n\n## Ectoparasiticides for Dogs and Cats (QP — Adjacent)\n\nAlthough classified under QP (antiparasitic products), the following are topical insecticides directly relevant to dermatological health of pets:\n\n### Comfortis (spinosad) — EMEA/V/C/002233\n\n- **ATCvet code**: QP53BX03\n- **INN**: Spinosad (INN: spinosad)\n- **Active substance**: spinosad\n- **Species**: Dogs;Cats\n- **Status**: Withdrawn\n- **Pharmacotherapeutic group**: Other ectoparasiticides for systemic use\n- **Therapeutic indication**: Treatment and prevention of flea infestations (*Ctenocephalides felis*). The preventive effect against re-infestations is maintained for 4 weeks.\n- **Marketing authorisation holder**: Elanco GmbH\n\n### Activyl Tick Plus (indoxacarb;permethrin) — EMEA/V/C/002234\n\n- **ATCvet code**: QP53AC54\n- **INN**: Indoxacarb;Permethrin (INN: indoxacarb; permethrin)\n- **Active substance**: indoxacarb; permethrin\n- **Species**: Dogs\n- **Status**: Withdrawn\n- **Pharmacotherapeutic group**: Ectoparasiticides for topical use, incl. insecticides\n- **Therapeutic indication**: Treatment of flea infestations (*Ctenocephalides felis*); the product has persistent insecticidal efficacy for up to 4 weeks against ticks.\n- **Marketing authorisation holder**: Intervet International BV\n\n### ProMeris (metaflumizone) — EMEA/V/C/000107\n\n- **ATCvet code**: QP53AX25\n- **INN**: Metaflumizone (INN: metaflumizone)\n- **Active substance**: metaflumizone\n- **Species**: Cats\n- **Status**: Withdrawn\n- **Pharmacotherapeutic group**: Ectoparasiticides for topical use, incl. insecticides\n- **Therapeutic indication**: Treatment and prevention of flea infestations (*Ctenocephalides canis* and *C. felis*) in cats.\n- **Marketing authorisation holder**: Pfizer Limited\n\n### ProMeris Duo (metaflumizone;amitraz) — EMEA/V/C/000108\n\n- **ATCvet code**: QP53AD51\n- **INN**: Metaflumizone;Amitraz (INN: metaflumizone; amitraz)\n- **Active substance**: metaflumizone; amitraz\n- **Species**: Dogs\n- **Status**: Withdrawn\n- **Pharmacotherapeutic group**: Ectoparasiticides for topical use, incl. insecticides\n- **Therapeutic indication**: For the treatment and prevention of infestations by fleas (*Ctenocephalides canis* and *C. felis*), and ticks (*Ixodes ricinus*, *Dermacentor reticulatus*, *Rhipicephalus sanguineus*) in dogs.\n- **Marketing authorisation holder**: Pfizer Limited\n\n### Certifect (fipronil/amitraz/(S)-methoprene) — EMEA/V/C/002002\n\n- **ATCvet code**: QP53AX65\n- **INN**: Fipronil / Amitraz / (S)-Methoprene (INN: fipronil; amitraz; (S)-methoprene)\n- **Active substance**: fipronil; amitraz; (S)-methoprene\n- **Species**: Dogs\n- **Status**: Withdrawn\n- **Pharmacotherapeutic group**: Ectoparasiticides for topical use, incl. insecticides\n- **Therapeutic indication**: Treatment and prevention of infestations in dogs by ticks (*Ixodes ricinus*, *Dermacentor reticulatus*, *Rhipicephalus sanguineus*) and fleas (*Ctenocephalides* spp.).\n- **Marketing authorisation holder**: Merial\n\n### Cheristin — EMEA/V/C/004316\n\n- **ATCvet code**: QP53AX\n- **Species**: Cats\n- **Status**: Application withdrawn\n- **Therapeutic indication**: For the treatment and prevention of flea infestations (*Ctenocephalides felis*) on cats.\n- **Marketing authorisation holder**: Elanco Europe Ltd\n\n## Key Facts\n\n1. **QD07AC90 = resocortol butyrate** — topical corticosteroid for acute localized moist dermatitis (hot spots) in dogs; MA holder Intervet International BV (EMEA/V/C/000048, Withdrawn).\n2. **QP53BX03 = spinosad** — systemic oral flea adulticide for dogs and cats; UK/CETMART brand Comfortis; Withdrawn.\n3. **QP53AC54 = indoxacarb + permethrin** — combination topical flea/tick product for dogs; Withdrawn.\n4. **QP53AX65 = fipronil + amitraz + (S)-methoprene** — triple-action topical ectoparasiticide for dogs; Withdrawn.\n5. All pet topical ectoparasiticides in the EMA database carry **Withdrawn** or **Application withdrawn** status, indicating these products are no longer marketed under their EMA MA numbers.\n\nSource: EMA medicines-output-medicines-report_en.xlsx, dataset generated 20/07/2026 - 18:00, accessed via `https://www.ema.europa.eu/en/medicines/download-medicine-data`.\n","sources":[],"tokens_estimated":260,"generated_at":null,"tip":"Use /api/v1/topics to discover more topics. /api/v1/nutrient for precise single-point queries. /api/v1/cross_compare for 2-3 standard comparisons."}