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Rabbit (Oryctolagus cuniculus) — Watanabe heritable hyperlipidemia (hereditary; OMIA-verified species predisposition)

companion_species_health_watanabe_heritable_hyperlipidemia_rabbit

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--- license: permission_granted topic_id: companion_species_health_watanabe_heritable_hyperlipidemia_rabbit category: companion-species-health title: "Rabbit (Oryctolagus cuniculus) — Watanabe heritable hyperlipidemia (hereditary; OMIA-verified species predisposition)" lang: en source: "OMIA (Online Mendelian Inheritance in Animals, University of Sydney) species-specific hereditary-disorder record, saved verbatim to source_file; C1 substring-verified. Pulled 2026-08-24 from local OMIA database dump." source_file: pdf-raw/species-health/rabbit_watanabe_heritable_hyperlipidemia_1124.txt date_parsed: 2026-08-24 tokens_estimated: 80 verification: method: substring_match claims: 3 passed: 3 date: 2026-08-24 recovered: false path: companion-species-health/companion_species_health_watanabe_heritable_hyperlipidemia_rabbit/01_companion_species_health_watanabe_heritable_hyperlipidemia_rabbit.md source_document: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" citation: authority: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" title: "Rabbit (Oryctolagus cuniculus) — Watanabe heritable hyperlipidemia (hereditary; OMIA-verified species predisposition)" url: "https://omia.org/OMIA000499/9986/" retrieved: "2026-08-24" ref: "OMIA species-specific hereditary-disorder records (omia.org), derived from local OMIA database dump; dataset: https://doi.org/10.25910/2AMR-PV70" doc_type: "academic animal-genetics database (species-specific disorder entries)" needs_review: false

verification_derived: method: derived_from_dataset source: "OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM" note: "Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose." verification_derived: method: derived_from_dataset source: "OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM" note: "Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose."---

Rabbit (Oryctolagus cuniculus) — Watanabe heritable hyperlipidemia (hereditary; OMIA-verified species predisposition)

Source: first-hand OMIA (University of Sydney) species-specific hereditary-disorder record, saved verbatim to source_file; every claim below is a C1 byte-substring of it.

Claims

  • Species: Rabbit (Oryctolagus cuniculus)
  • Disorder: Watanabe heritable hyperlipidemia
  • Summary: In addition to naturally-occurring variants for this trait, variants have been created artificially: Genetically-modifed organism; GMO.

Evidence (references)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

  • 1993. Is the Watanabe Heritable Hyperlipidemic Rabbit a Suitable Experimental Model for Percutaneous Transluminal Coronary Angioplasty in Humans? - A Light Microscopic, Immunohistochemical and Ultrastructural Study. Journal of the American College of Cardiology — PubMed:PMID8473661 — OMIA Phene_Article / Article
  • 1993. Absence of Glomerulosclerosis in Watanabe Heritable Hyperlipidemic Rabbits. Nephron — PubMed:PMID8502322 — OMIA Phene_Article / Article
  • 1993. Natural History of Atherosclerosis and Hyperlipidemia in Heterozygous WHHL (WHHL-Hh) Rabbits .1. The Effects of Aging and Gender on Plasma Lipids and Lipoproteins. Journal of Laboratory and Clinical Medicine — PubMed:PMID8426086 — OMIA Phene_Article / Article
  • 1993. Natural History of Atherosclerosis and Hyperlipidemia in Heterozygous WHHL (WHHL-Hh) Rabbits .2. Morphologic Evaluation of Spontaneously Occurring Aortic and Coronary Lesions. Journal of Laboratory and Clinical Medicine — PubMed:PMID8426070 — OMIA Phene_Article / Article
  • 1993. Invivo Kinetics of Lipoprotein(a) in Homozygous Watanabe Heritable Hyperlipidaemic Rabbits. European Journal of Clinical Investigation — PubMed:PMID8243527 — OMIA Phene_Article / Article
  • 1993. The Effects of High Levels of Vitamin-E on the Progression of Atherosclerosis in the Watanabe Heritable Hyperlipidemic Rabbit. Journal of Nutritional Biochemistry — OMIA Phene_Article / Article
  • 1993. Increased Platelet GPIIb/IIIa Receptor Sensitivity in Watanabe Heritable Hyperlipidemic Rabbits. Biochemical Archives — OMIA Phene_Article / Article
  • 1993. Hyperreactivity of Aortic Smooth Muscle to Serotonin Is Related to the Presence of Atheroma in Watanabe Heritable Hyperlipidaemic Rabbits. Cardiovascular Research — PubMed:PMID8313424 — OMIA Phene_Article / Article
  • 1994. Whole Blood and Plasma Concentrations of 4-Hydroxy-2-Nonenal in Watanabe Heritable Hyperlipidemic Versus New Zealand White Rabbits. Biochemical and Biophysical Research Communications — PubMed:PMID8135808 | DOI:10.1006/bbrc.1994.1280 — OMIA Phene_Article / Article
  • 1994. In Vivo Correction of Low Density Lipoprotein Receptor Deficiency in the Watanabe Heritable Hyperlipidemic Rabbit with Recombinant Adenoviruses. Journal of Biological Chemistry — PubMed:PMID8175805 — OMIA Phene_Article / Article
  • 1994. Increased mRNA for CD63 antigen in atherosclerotic lesions of Watanabe heritable hyperlipidemic rabbits. Cell Structure and Function — PubMed:PMID7820873 — OMIA Phene_Article / Article
  • 1994. Expression of mRNA for matrix gamma-carboxyglutamic acid protein during progression of atherosclerosis in aortae of Watanabe heritable hyperlipidemic rabbits. Journal of Biochemistry — PubMed:PMID7883748 — OMIA Phene_Article / Article
  • (60 additional references in OMIA)

Comparative medicine (human OMIM)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

  • OMIM:143890 (type: trait) — OMIA Group_OMIM (via OMIA_ID)
  • OMIM:606945 (type: gene) — OMIA Group_OMIM (via OMIA_ID)

Evidence (references)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

  • 1993. Is the Watanabe Heritable Hyperlipidemic Rabbit a Suitable Experimental Model for Percutaneous Transluminal Coronary Angioplasty in Humans? - A Light Microscopic, Immunohistochemical and Ultrastructural Study. Journal of the American College of Cardiology — PubMed:PMID8473661 — OMIA Phene_Article / Article
  • 1993. Absence of Glomerulosclerosis in Watanabe Heritable Hyperlipidemic Rabbits. Nephron — PubMed:PMID8502322 — OMIA Phene_Article / Article
  • 1993. Natural History of Atherosclerosis and Hyperlipidemia in Heterozygous WHHL (WHHL-Hh) Rabbits .1. The Effects of Aging and Gender on Plasma Lipids and Lipoproteins. Journal of Laboratory and Clinical Medicine — PubMed:PMID8426086 — OMIA Phene_Article / Article
  • 1993. Natural History of Atherosclerosis and Hyperlipidemia in Heterozygous WHHL (WHHL-Hh) Rabbits .2. Morphologic Evaluation of Spontaneously Occurring Aortic and Coronary Lesions. Journal of Laboratory and Clinical Medicine — PubMed:PMID8426070 — OMIA Phene_Article / Article
  • 1993. Invivo Kinetics of Lipoprotein(a) in Homozygous Watanabe Heritable Hyperlipidaemic Rabbits. European Journal of Clinical Investigation — PubMed:PMID8243527 — OMIA Phene_Article / Article
  • 1993. The Effects of High Levels of Vitamin-E on the Progression of Atherosclerosis in the Watanabe Heritable Hyperlipidemic Rabbit. Journal of Nutritional Biochemistry — OMIA Phene_Article / Article
  • 1993. Increased Platelet GPIIb/IIIa Receptor Sensitivity in Watanabe Heritable Hyperlipidemic Rabbits. Biochemical Archives — OMIA Phene_Article / Article
  • 1993. Hyperreactivity of Aortic Smooth Muscle to Serotonin Is Related to the Presence of Atheroma in Watanabe Heritable Hyperlipidaemic Rabbits. Cardiovascular Research — PubMed:PMID8313424 — OMIA Phene_Article / Article
  • 1994. Whole Blood and Plasma Concentrations of 4-Hydroxy-2-Nonenal in Watanabe Heritable Hyperlipidemic Versus New Zealand White Rabbits. Biochemical and Biophysical Research Communications — PubMed:PMID8135808 | DOI:10.1006/bbrc.1994.1280 — OMIA Phene_Article / Article
  • 1994. In Vivo Correction of Low Density Lipoprotein Receptor Deficiency in the Watanabe Heritable Hyperlipidemic Rabbit with Recombinant Adenoviruses. Journal of Biological Chemistry — PubMed:PMID8175805 — OMIA Phene_Article / Article
  • 1994. Increased mRNA for CD63 antigen in atherosclerotic lesions of Watanabe heritable hyperlipidemic rabbits. Cell Structure and Function — PubMed:PMID7820873 — OMIA Phene_Article / Article
  • 1994. Expression of mRNA for matrix gamma-carboxyglutamic acid protein during progression of atherosclerosis in aortae of Watanabe heritable hyperlipidemic rabbits. Journal of Biochemistry — PubMed:PMID7883748 — OMIA Phene_Article / Article
  • (60 additional references in OMIA)

Comparative medicine (human OMIM)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

  • OMIM:143890 (type: trait) — OMIA Group_OMIM (via OMIA_ID)
  • OMIM:606945 (type: gene) — OMIA Group_OMIM (via OMIA_ID)

Sources

Rabbit (Oryctolagus cuniculus) — Watanabe heritable hyperlipidemia (hereditary; OMIA-verified species predisposition)
companion-species-healthPMID 8473661

Machine access

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