--- license: permission_granted topic_id: companion_species_health_pelger_huet_anomaly_rabbit category: companion-species-health title: "Rabbit (Oryctolagus cuniculus) — Pelger-Huet anomaly (hereditary; OMIA-verified species predisposition)" lang: en source: "OMIA (Online Mendelian Inheritance in Animals, University of Sydney) species-specific hereditary-disorder record, saved verbatim to source_file; C1 substring-verified. Pulled 2026-08-24 from local OMIA database dump." source_file: pdf-raw/species-health/rabbit_pelger_huet_anomaly_1423.txt date_parsed: 2026-08-24 tokens_estimated: 113 verification: method: substring_match claims: 4 passed: 4 date: 2026-08-24 recovered: false path: companion-species-health/companion_species_health_pelger_huet_anomaly_rabbit/01_companion_species_health_pelger_huet_anomaly_rabbit.md source_document: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" citation: authority: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" title: "Rabbit (Oryctolagus cuniculus) — Pelger-Huet anomaly (hereditary; OMIA-verified species predisposition)" url: "https://omia.org/OMIA000783/9986/" retrieved: "2026-08-24" ref: "OMIA species-specific hereditary-disorder records (omia.org), derived from local OMIA database dump; dataset: https://doi.org/10.25910/2AMR-PV70" doc_type: "academic animal-genetics database (species-specific disorder entries)" needs_review: false
verification_derived: method: derived_from_dataset source: "OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM" note: "Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose."---
Rabbit (Oryctolagus cuniculus) — Pelger-Huet anomaly (hereditary; OMIA-verified species predisposition)
Source: first-hand OMIA (University of Sydney) species-specific hereditary-disorder record, saved verbatim to source_file; every claim below is a C1 byte-substring of it.
Claims
Species: Rabbit (Oryctolagus cuniculus)Disorder: Pelger-Huet anomalyMode of inheritance: Undritz (1939) and Nachsteim (1950) presented evidence of single-locus inheritance, with heterozygotes showing the disorder and homozygotes showing an extreme form of the disorder, including chondrodysplasia, that results in neonatal death in almost all cases.Summary: See Robinson (1958, pp. 354-355).
Associated gene(s)
Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.
- OMIA entry symbol: Pg (no structured Phene_Gene link)
Evidence (references)
Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.
- 1977. [Studies on the frequency of the Pelger anomaly in the domestic rabbit population]. Zentralbl Veterinarmed A — PubMed:PMID407754 — OMIA Phene_Article / Article
- 1958. Genetic studies of the rabbit. Bibliographia Genetica — OMIA Phene_Article / Article
- 1950. The Pelger-anomaly in man and rabbit; a mendelian character of the nuclei of the leucocytes. J Hered — PubMed:PMID15436969 | DOI:10.1093/oxfordjournals.jhered.a106108 — OMIA Phene_Article / Article
- 1952. Beitrage zur Morphologic und Gtnetik der Pelger-Anomalie bei Mensch und Kaninchen [Morphology and genetics of the Pelger anomaly in man and the rabbit]. Zeitschrift fur menschliche Vererbungs- und Konstitutionslehre — OMIA Phene_Article / Article
- 1939. Das Pelger-Huetsche Blutbild beim Tier und seine Bedeutung fiir die Entwicklungsgeschichte des Blutes. Schweizerische medizinische Wochenschrift — OMIA Phene_Article / Article
- 1943. Das ausschliessliche Vorkommen reifer rundkerniger Leukozyten bei der reingezüchteten Pelger−Huëtschen Anomalie des Kaninchens und die Bedeutung der Pelger−Leukozyten in der vergleichenden Hämatologie. Folia Haemat. — OMIA Phene_Article / Article
- 1949. Die Pelger-Anomalie der Leukocyten und die pathologische Anatomie des neugeborenen homozygoten Pelger-Kaninchens. Zeitschrift fur menschliche Vererbungs- und Konstitutionslehre — OMIA Phene_Article / Article
- 2003. Congenital abnormalities reported in Pelger-Huët homozygosity as compared to Greenberg/HEM dysplasia: highly variable expression of allelic phenotypes. J Med Genet — PubMed:PMID14684694 | DOI:10.1136/jmg.40.12.937 — OMIA Phene_Article / Article
- 1964. [On the activity of neutrophilic alkaline phosphatase with Pelger-Huet anomaly in rabbits]. Patol Pol — PubMed:PMID14241274 — OMIA Phene_Article / Article
- 1953. [Effect of colchicine on the white blood picture of Pelger and non-Pelger rabbits]. Acta Haematol — PubMed:PMID13091700 — OMIA Phene_Article / Article
Comparative medicine (human OMIM)
Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.
- OMIM:169400 (type: trait) — OMIA Group_OMIM (via OMIA_ID)