--- license: permission_granted topic_id: companion_species_health_omia_4806_hamster category: companion-species-health title: "Hamster — Cancer, TP53-related (hereditary; OMIA-verified species predisposition)" lang: en source: "OMIA (Online Mendelian Inheritance in Animals, University of Sydney) species-specific hereditary-disorder record, saved verbatim to source_file; C1 substring-verified. Pulled 2026-08-24 from local OMIA database dump." source_file: pdf-raw/species-health/hamster_omia_4806_4806.txt date_parsed: 2026-08-24 tokens_estimated: 80 verification: method: substring_match claims: 4 passed: 4 date: 2026-08-24 recovered: false path: companion-species-health/companion_species_health_omia_4806_hamster/01_companion_species_health_omia_4806_hamster.md source_document: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" citation: authority: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" title: "Hamster — Cancer, TP53-related (hereditary; OMIA-verified species predisposition)" url: "https://omia.org/OMIA001990/10036/" retrieved: "2026-08-24" ref: "OMIA species-specific hereditary-disorder records (omia.org), derived from local OMIA database dump; dataset: https://doi.org/10.25910/2AMR-PV70" doc_type: "academic animal-genetics database (species-specific disorder entries)" needs_review: false
verification_derived: method: derived_from_dataset source: "OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM" note: "Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose."---
Hamster — Cancer, TP53-related (hereditary; OMIA-verified species predisposition)
Source: first-hand OMIA (University of Sydney) species-specific hereditary-disorder record, saved verbatim to source_file; every claim below is a C1 byte-substring of it.
Claims
Species: Mesocricetus auratus / Phodopus spp. (hamster)Disorder:Summary: Miao et al. (2021) describe a cancer phenotype in TP53 knockout golden Syrian hamsters. This phene includes references to studies involving genetically modified organisms (GMO).Defect: yes
Associated gene(s)
Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.
- Gene: Entrez Gene ID 398298960 (no symbol in OMIA GeneSynonym) — OMIA Phene_Gene
Evidence (references)
Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.
- 2021. Cancer spectrum in TP53-deficient golden Syrian hamsters: A new model for Li-Fraumeni syndrome. J Carcinog — PubMed:PMID34729050 | DOI:10.4103/jcar.jcar_18_21 — OMIA Phene_Article / Article
Comparative medicine (human OMIM)
Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.
- OMIM:109800 (type: trait) — OMIA Group_OMIM (via OMIA_ID)
- OMIM:114480 (type: trait) — OMIA Group_OMIM (via OMIA_ID)
- OMIM:137215 (type: trait) — OMIA Group_OMIM (via OMIA_ID)
- OMIM:601626 (type: trait) — OMIA Group_OMIM (via OMIA_ID)
- OMIM:211980 (type: trait) — OMIA Group_OMIM (via OMIA_ID)
- OMIM:260350 (type: trait) — OMIA Group_OMIM (via OMIA_ID)
- OMIM:614470 (type: trait) — OMIA Group_OMIM (via OMIA_ID)
- OMIM:202300 (type: trait) — OMIA Group_OMIM (via OMIA_ID)
- OMIM:114500 (type: trait) — OMIA Group_OMIM (via OMIA_ID)
- OMIM:114550 (type: trait) — OMIA Group_OMIM (via OMIA_ID)
- OMIM:607107 (type: trait) — OMIA Group_OMIM (via OMIA_ID)
- OMIM:259500 (type: trait) — OMIA Group_OMIM (via OMIA_ID)
- OMIM:614740 (type: trait) — OMIA Group_OMIM (via OMIA_ID)
- OMIM:137800 (type: trait) — OMIA Group_OMIM (via OMIA_ID)
- OMIM:191170 (type: gene) — OMIA Group_OMIM (via OMIA_ID)
- OMIM:190070 (type: gene) — OMIA Group_OMIM (via OMIA_ID)
- OMIM:151623 (type: trait) — OMIA Group_OMIM (via OMIA_ID)