{"topic_id":"companion_species_health_omia_4806_hamster","category":"companion-species-health","context":"---\nlicense: permission_granted\ntopic_id: companion_species_health_omia_4806_hamster\ncategory: companion-species-health\ntitle: \"Hamster — Cancer, TP53-related (hereditary; OMIA-verified species predisposition)\"\nlang: en\nsource: \"OMIA (Online Mendelian Inheritance in Animals, University of Sydney) species-specific hereditary-disorder record, saved verbatim to source_file; C1 substring-verified. Pulled 2026-08-24 from local OMIA database dump.\"\nsource_file: pdf-raw/species-health/hamster_omia_4806_4806.txt\ndate_parsed: 2026-08-24\ntokens_estimated: 80\nverification:\n  method: substring_match\n  claims: 4\n  passed: 4\n  date: 2026-08-24\nrecovered: false\npath: companion-species-health/companion_species_health_omia_4806_hamster/01_companion_species_health_omia_4806_hamster.md\nsource_document: \"OMIA — Online Mendelian Inheritance in Animals (University of Sydney)\"\ncitation:\n  authority: \"OMIA — Online Mendelian Inheritance in Animals (University of Sydney)\"\n  title: \"Hamster — Cancer, TP53-related (hereditary; OMIA-verified species predisposition)\"\n  url: \"https://omia.org/OMIA001990/10036/\"\n  retrieved: \"2026-08-24\"\n  ref: \"OMIA species-specific hereditary-disorder records (omia.org), derived from local OMIA database dump; dataset: https://doi.org/10.25910/2AMR-PV70\"\n  doc_type: \"academic animal-genetics database (species-specific disorder entries)\"\n  needs_review: false\n\nverification_derived:\n  method: derived_from_dataset\n  source: \"OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM\"\n  note: \"Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose.\"---\n\n# Hamster — Cancer, TP53-related (hereditary; OMIA-verified species predisposition)\n\nSource: first-hand OMIA (University of Sydney) species-specific hereditary-disorder record, saved verbatim to `source_file`; every claim below is a C1 byte-substring of it.\n\n## Claims\n\n- `Species: Mesocricetus auratus / Phodopus spp. (hamster)`\n- `Disorder: `\n- `Summary: Miao et al. (2021) describe a cancer phenotype in TP53 knockout golden Syrian hamsters. This phene includes references to studies involving genetically modified organisms (GMO).`\n- `Defect: yes`\n## Associated gene(s)\nDerived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.\n- Gene: Entrez Gene ID 398298960 (no symbol in OMIA GeneSynonym) — OMIA Phene_Gene\n\n## Evidence (references)\nDerived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.\n- 2021. Cancer spectrum in TP53-deficient golden Syrian hamsters: A new model for Li-Fraumeni syndrome. J Carcinog — PubMed:PMID34729050 | DOI:10.4103/jcar.jcar_18_21 — OMIA Phene_Article / Article\n\n## Comparative medicine (human OMIM)\nDerived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.\n- OMIM:109800 (type: trait) — OMIA Group_OMIM (via OMIA_ID)\n- OMIM:114480 (type: trait) — OMIA Group_OMIM (via OMIA_ID)\n- OMIM:137215 (type: trait) — OMIA Group_OMIM (via OMIA_ID)\n- OMIM:601626 (type: trait) — OMIA Group_OMIM (via OMIA_ID)\n- OMIM:211980 (type: trait) — OMIA Group_OMIM (via OMIA_ID)\n- OMIM:260350 (type: trait) — OMIA Group_OMIM (via OMIA_ID)\n- OMIM:614470 (type: trait) — OMIA Group_OMIM (via OMIA_ID)\n- OMIM:202300 (type: trait) — OMIA Group_OMIM (via OMIA_ID)\n- OMIM:114500 (type: trait) — OMIA Group_OMIM (via OMIA_ID)\n- OMIM:114550 (type: trait) — OMIA Group_OMIM (via OMIA_ID)\n- OMIM:607107 (type: trait) — OMIA Group_OMIM (via OMIA_ID)\n- OMIM:259500 (type: trait) — OMIA Group_OMIM (via OMIA_ID)\n- OMIM:614740 (type: trait) — OMIA Group_OMIM (via OMIA_ID)\n- OMIM:137800 (type: trait) — OMIA Group_OMIM (via OMIA_ID)\n- OMIM:191170 (type: gene) — OMIA Group_OMIM (via OMIA_ID)\n- OMIM:190070 (type: gene) — OMIA Group_OMIM (via OMIA_ID)\n- OMIM:151623 (type: trait) — OMIA Group_OMIM (via OMIA_ID)\n","sources":["companion-species-health — Hamster — Cancer, TP53-related (hereditary; OMIA-verified species predisposition)"],"source":{"authority":"companion-species-health","title":"Hamster — Cancer, TP53-related (hereditary; OMIA-verified species predisposition)","url":"https://pubmed.ncbi.nlm.nih.gov/34729050/","retrieved":"","ref":"PMID 34729050","doc_type":"official source","source_document":"","verification_file":""},"source_document":"","source_file":"","trust":{"authority_tier":"ungraded","fidelity":"verbatim","license":null,"display_grade":"pending"},"tokens_estimated":657,"generated_at":null,"tip":"Use /api/v1/topics to discover more topics. /api/v1/nutrient for precise single-point queries. /api/v1/cross_compare for 2-3 standard comparisons."}