--- license: permission_granted topic_id: companion_species_health_omia_3236_hamster category: companion-species-health title: "Hamster — Duper (hereditary; OMIA-verified species predisposition)" lang: en source: "OMIA (Online Mendelian Inheritance in Animals, University of Sydney) species-specific hereditary-disorder record, saved verbatim to source_file; C1 substring-verified. Pulled 2026-08-24 from local OMIA database dump." source_file: pdf-raw/species-health/hamster_omia_3236_3236.txt date_parsed: 2026-08-24 tokens_estimated: 116 verification: method: substring_match claims: 4 passed: 4 date: 2026-08-24 recovered: false path: companion-species-health/companion_species_health_omia_3236_hamster/01_companion_species_health_omia_3236_hamster.md source_document: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" citation: authority: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" title: "Hamster — Duper (hereditary; OMIA-verified species predisposition)" url: "https://omia.org/OMIA001643/10036/" retrieved: "2026-08-24" ref: "OMIA species-specific hereditary-disorder records (omia.org), derived from local OMIA database dump; dataset: https://doi.org/10.25910/2AMR-PV70" doc_type: "academic animal-genetics database (species-specific disorder entries)" needs_review: false
verification_derived: method: derived_from_dataset source: "OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM" note: "Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose."---
Hamster — Duper (hereditary; OMIA-verified species predisposition)
Source: first-hand OMIA (University of Sydney) species-specific hereditary-disorder record, saved verbatim to source_file; every claim below is a C1 byte-substring of it.
Claims
Species: Mesocricetus auratus / Phodopus spp. (hamster)Disorder:Summary: Lee et al. (2022): "The duper mutation is a recessive mutation that shortens the period length of the circadian rhythm in Syrian hamsters. These animals show a large phase shift when responding to light pulses. ... we identified duper as an early nonsense allele of Cryptochrome 1 (Cry1) leading to a short, unstable protein ..."Defect: no
Associated gene(s)
Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.
- Gene: Entrez Gene ID 392717204 (no symbol in OMIA GeneSynonym) — OMIA Phene_Gene
Evidence (references)
Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.
- 2011. Duper: a mutation that shortens hamster circadian period. J Biol Rhythms — PubMed:PMID21775287 | DOI:10.1177/0748730411411569 — OMIA Phene_Article / Article
- 2011. Effects of the duper mutation on circadian responses to light. J Biol Rhythms — PubMed:PMID21775288 | DOI:10.1177/0748730411411570 — OMIA Phene_Article / Article
- 2022. duper is a null mutation of cryptochrome 1 in Syrian hamsters. Proc Natl Acad Sci U S A — PubMed:PMID35471909 | DOI:10.1073/pnas.2123560119 — OMIA Phene_Article / Article
- 2023. Adult neurogenesis is altered by circadian phase shifts and the duper mutation in female Syrian hamsters. eNeuro — PubMed:PMID36878716 | DOI:10.1523/ENEURO.0359-22.2023 — OMIA Phene_Article / Article
- 2024. Neuroendocrine effects of the duper mutation in Syrian hamsters: a role for Cryptochrome 1. Front Physiol — PubMed:PMID38444761 | DOI:10.3389/fphys.2024.1351682 — OMIA Phene_Article / Article