← All Topics / companion-species-health

Rabbit (Oryctolagus cuniculus) — maxillary brachygnathism, congenital malocclusion, mandibular prognathism, crossbite (hereditary; OMIA-verified species predisposition)

companion_species_health_maxillary_brachygnathism_congenital_malocclusion_mandibular__rabbit

companion-species-health en

--- license: permission_granted topic_id: companion_species_health_maxillary_brachygnathism_congenital_malocclusion_mandibular__rabbit category: companion-species-health title: "Rabbit (Oryctolagus cuniculus) — maxillary brachygnathism, congenital malocclusion, mandibular prognathism, crossbite (hereditary; OMIA-verified species predisposition)" lang: en source: "OMIA (Online Mendelian Inheritance in Animals, University of Sydney) species-specific hereditary-disorder record, saved verbatim to source_file; C1 substring-verified. Pulled 2026-08-24 from local OMIA database dump." source_file: pdf-raw/species-health/rabbit_maxillary_brachygnathism_congenital_malocclusion_mandibular__2155.txt date_parsed: 2026-08-24 tokens_estimated: 247 verification: method: substring_match claims: 5 passed: 5 date: 2026-08-24 recovered: false path: companion-species-health/companion_species_health_maxillary_brachygnathism_congenital_malocclusion_mandibular__rabbit/01_companion_species_health_maxillary_brachygnathism_congenital_malocclusion_mandibular__rabbit.md source_document: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" citation: authority: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" title: "Rabbit (Oryctolagus cuniculus) — maxillary brachygnathism, congenital malocclusion, mandibular prognathism, crossbite (hereditary; OMIA-verified species predisposition)" url: "https://omia.org/OMIA000149/9986/" retrieved: "2026-08-24" ref: "OMIA species-specific hereditary-disorder records (omia.org), derived from local OMIA database dump; dataset: https://doi.org/10.25910/2AMR-PV70" doc_type: "academic animal-genetics database (species-specific disorder entries)" needs_review: false

verification_derived: method: derived_from_dataset source: "OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM" note: "Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose." verification_derived: method: derived_from_dataset source: "OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM" note: "Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose."---

Rabbit (Oryctolagus cuniculus) — maxillary brachygnathism, congenital malocclusion, mandibular prognathism, crossbite (hereditary; OMIA-verified species predisposition)

Source: first-hand OMIA (University of Sydney) species-specific hereditary-disorder record, saved verbatim to source_file; every claim below is a C1 byte-substring of it.

Claims

  • Species: Rabbit (Oryctolagus cuniculus)
  • Disorder: maxillary brachygnathism, congenital malocclusion, mandibular prognathism, crossbite
  • Mode of inheritance: Nachtheim (1937) suggested a recessive mode of inheritance. Huang et al. (1981) proposed a "simple autosomal recessive inheritance with incomplete penetrance for this condition". Korn et al. (2016) estimated heritability to be 25%.
  • Summary: Disproportions in jaw length between upper and lower jaw result in teeth that are not positioned correctly and to dental malocclusion. Brachygnathia superior is observed in rabbits, most frequently in dwarf breeds.
  • Clin feat: In rabbits, teeth grow throughout their life. Rabbits with brachygnathia superior can have severely overgrown teeth due to abnormal wear. This can result in difficulties to feed and groom and associated severe health problems (Harcourt-Brown 1997, 2009). Affected animals require regular veterinary treatment.

Evidence (references)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

  • 1974. Inheritance of brachygnathia superior in rabbits. Zeitschrift fur Tierzuchtung und Zuchtungsbiologie — OMIA Phene_Article / Article
  • 1958. Genetic studies of the rabbit. Bibliographia Genetica — OMIA Phene_Article / Article
  • 2016. Genetic and environmental factors influencing tooth and jaw malformations in rabbits. Vet Rec — PubMed:PMID26908159 | DOI:10.1136/vr.103293 — OMIA Phene_Article / Article
  • 1937. Erbpathologische Untersuchungen am Kaninchen [Investigation of inherited defects in rabbits]. Z. indo Abst. u. Vererbgs — DOI:10.1007/BF01847500 — OMIA Phene_Article / Article
  • 2016. Breeding for good dental and oral health in rabbits. [Comment on Genetic and environmental factors influencing tooth and jaw malformations in rabbits; Vet Rec. 2016 Apr 2;178(14):341]. Vet Rec — PubMed:PMID27034298 | DOI:10.1136/vr.i1808 — OMIA Phene_Article / Article
  • 1981. Mandibular prognathism in the rabbit: discrimination between single-locus and multifactorial models of inheritance. J Hered — PubMed:PMID7288146 | DOI:10.1093/oxfordjournals.jhered.a109507 — OMIA Phene_Article / Article
  • 1971. Mandibular prognathism in the rabbit. Genetic studies. J Hered — PubMed:PMID5094712 | DOI:10.1093/oxfordjournals.jhered.a108111 — OMIA Phene_Article / Article
  • 1967. J Hered — DOI:10.1093/oxfordjournals.jhered.a107602 — OMIA Phene_Article / Article
  • 1997. Diagnosis, treatment and prognosis of dental disease in pet rabbits. In Practice — DOI:10.1136/inpract.19.8.407 — OMIA Phene_Article / Article
  • 2009. Dental disease in pet rabbits. In Practice — DOI:10.1136/inpract.31.8.370 — OMIA Phene_Article / Article
  • 2021. Exceptional changes in skeletal anatomy under domestication: The case of brachycephaly. Integr Org Biol — PubMed:PMID34409262 | DOI:10.1093/iob/obab023 — OMIA Phene_Article / Article
  • 2025. Rethinking brachycephaly: Anatomical implications and health considerations in lagomorphs. Anat Rec (Hoboken) — PubMed:PMID41431133 | DOI:10.1002/ar.70123 — OMIA Phene_Article / Article

Evidence (references)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

  • 1974. Inheritance of brachygnathia superior in rabbits. Zeitschrift fur Tierzuchtung und Zuchtungsbiologie — OMIA Phene_Article / Article
  • 1958. Genetic studies of the rabbit. Bibliographia Genetica — OMIA Phene_Article / Article
  • 2016. Genetic and environmental factors influencing tooth and jaw malformations in rabbits. Vet Rec — PubMed:PMID26908159 | DOI:10.1136/vr.103293 — OMIA Phene_Article / Article
  • 1937. Erbpathologische Untersuchungen am Kaninchen [Investigation of inherited defects in rabbits]. Z. indo Abst. u. Vererbgs — DOI:10.1007/BF01847500 — OMIA Phene_Article / Article
  • 2016. Breeding for good dental and oral health in rabbits. [Comment on Genetic and environmental factors influencing tooth and jaw malformations in rabbits; Vet Rec. 2016 Apr 2;178(14):341]. Vet Rec — PubMed:PMID27034298 | DOI:10.1136/vr.i1808 — OMIA Phene_Article / Article
  • 1981. Mandibular prognathism in the rabbit: discrimination between single-locus and multifactorial models of inheritance. J Hered — PubMed:PMID7288146 | DOI:10.1093/oxfordjournals.jhered.a109507 — OMIA Phene_Article / Article
  • 1971. Mandibular prognathism in the rabbit. Genetic studies. J Hered — PubMed:PMID5094712 | DOI:10.1093/oxfordjournals.jhered.a108111 — OMIA Phene_Article / Article
  • 1967. J Hered — DOI:10.1093/oxfordjournals.jhered.a107602 — OMIA Phene_Article / Article
  • 1997. Diagnosis, treatment and prognosis of dental disease in pet rabbits. In Practice — DOI:10.1136/inpract.19.8.407 — OMIA Phene_Article / Article
  • 2009. Dental disease in pet rabbits. In Practice — DOI:10.1136/inpract.31.8.370 — OMIA Phene_Article / Article
  • 2021. Exceptional changes in skeletal anatomy under domestication: The case of brachycephaly. Integr Org Biol — PubMed:PMID34409262 | DOI:10.1093/iob/obab023 — OMIA Phene_Article / Article
  • 2025. Rethinking brachycephaly: Anatomical implications and health considerations in lagomorphs. Anat Rec (Hoboken) — PubMed:PMID41431133 | DOI:10.1002/ar.70123 — OMIA Phene_Article / Article

Sources

Rabbit (Oryctolagus cuniculus) — maxillary brachygnathism, congenital malocclusion, mandibular prognathism, crossbite (hereditary; OMIA-verified species predisposition)
companion-species-healthPMID 26908159

Machine access

AI agents: this page mirrors GET /api/v1/llm_context?topic=companion_species_health_maxillary_brachygnathism_congenital_malocclusion_mandibular__rabbit (max 500 tokens, whitelisted). Rate limit 60 req/min for recognized AI crawlers.

Raw JSON ↗ llm.txt OpenAPI