--- license: permission_granted topic_id: companion_breed_health_peruvian_paso_horse_inherited_myoclonus_horse category: companion-breed-health title: "Peruvian Paso (Horse) — inherited myoclonus (hereditary; OMIA-verified breed predisposition)" lang: en source: "OMIA (Online Mendelian Inheritance in Animals, University of Sydney) breed-specific hereditary-disorder record, saved verbatim to source_file; C1 substring-verified. Pulled 2026-08-23 from local OMIA database dump." source_file: pdf-raw/breed-health/peruvian_paso_horse_inherited_myoclonus_1291.txt date_parsed: 2026-08-23 tokens_estimated: 192 verification: method: substring_match claims: 4 passed: 4 date: 2026-08-23 recovered: false path: companion-breed-health/companion_breed_health_peruvian_paso_horse_inherited_myoclonus_horse/01_companion_breed_health_peruvian_paso_horse_inherited_myoclonus_horse.md source_document: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" citation: authority: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" title: "Peruvian Paso (Horse) — inherited myoclonus (hereditary; OMIA-verified breed predisposition)" url: "https://omia.org/OMIA000689/9796/" retrieved: "2026-08-23" ref: "OMIA breed-specific hereditary-disorder records (omia.org), derived from local OMIA database dump; dataset: https://doi.org/10.25910/2AMR-PV70" doc_type: "academic animal-genetics database (breed-specific disorder entries)" needs_review: false
verification_derived: method: derived_from_dataset source: "OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM" note: "Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose." verification_derived: method: derived_from_dataset source: "OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM" note: "Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose."---
Peruvian Paso (Horse) — inherited myoclonus (hereditary; OMIA-verified breed predisposition)
Source: first-hand OMIA (University of Sydney) breed-specific hereditary-disorder record, saved verbatim to source_file; every claim below is a C1 byte-substring of it.
Claims
Breed: Peruvian Paso (Horse)Disorder: inherited myoclonusSummary: Gundlach et al. (1993) report the occurrence of ... [a] stimulus-induced myoclonus in individual, pure-bred Peruvian Paso horses and an associated, specific deficiency in the density of [3H]strychnine binding to inhibitory glycine receptors sites in spinal cord of these animals. The authors suggest that the disease is similar to inherited myoclonus in Poll Hereford calves (see OMIA:000689-9913 : Hyperekplexia, GLRA1-related in Bos taurus). However, the underlying molecular genetic cause in horses has not been identified, and the disease in horses and may not be associated with variants in the GLRA1 gene.Defect: yes
Evidence (references)
Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.
- 1993. Deficit of inhibitory glycine receptors in spinal cord from Peruvian Pasos - Evidence for an equine form of inherited myoclonus. Brain Res — PubMed:PMID8313155 | DOI:10.1016/0006-8993(93)90963-n — OMIA Phene_Article / Article
Comparative medicine (human OMIM)
Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.
- OMIM:149400 (type: trait) — OMIA Group_OMIM (via OMIA_ID)
- OMIM:138491 (type: gene) — OMIA Group_OMIM (via OMIA_ID)
Evidence (references)
Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.
- 1993. Deficit of inhibitory glycine receptors in spinal cord from Peruvian Pasos - Evidence for an equine form of inherited myoclonus. Brain Res — PubMed:PMID8313155 | DOI:10.1016/0006-8993(93)90963-n — OMIA Phene_Article / Article
Comparative medicine (human OMIM)
Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.
- OMIM:149400 (type: trait) — OMIA Group_OMIM (via OMIA_ID)
- OMIM:138491 (type: gene) — OMIA Group_OMIM (via OMIA_ID)