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Keeshond — Tetralogy of Fallot (hereditary; OMIA-verified breed predisposition)

companion_breed_health_keeshond_omia1723_dog

companion-breed-health en

--- license: permission_granted topic_id: companion_breed_health_keeshond_omia1723_dog category: companion-breed-health title: "Keeshond — Tetralogy of Fallot (hereditary; OMIA-verified breed predisposition)" lang: en source: "OMIA (Online Mendelian Inheritance in Animals, University of Sydney) breed-specific hereditary-disorder record, saved verbatim to source_file; C1 substring-verified. Pulled 2026-08-02 from local OMIA database dump." source_file: pdf-raw/breed-health/keeshond_omia1723_1723.txt date_parsed: 2026-08-02 tokens_estimated: 80 verification: method: substring_match claims: 5 passed: 5 date: 2026-08-02 recovered: false path: companion-breed-health/companion_breed_health_keeshond_omia1723_dog/01_companion_breed_health_keeshond_omia1723_dog.md source_document: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" citation: authority: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" title: "Keeshond — Tetralogy of Fallot (hereditary; OMIA-verified breed predisposition)" url: "https://omia.org/OMIA000994/9615/" retrieved: "2026-08-02" ref: "OMIA breed-specific hereditary-disorder records (omia.org), derived from local OMIA database dump; dataset: https://doi.org/10.25910/2AMR-PV70" doc_type: "academic animal-genetics database (breed-specific disorder entries)" needs_review: false

Keeshond — Tetralogy of Fallot (hereditary; OMIA-verified breed predisposition)

Source: first-hand OMIA (University of Sydney) breed-specific hereditary-disorder record, saved verbatim to source_file; every claim below is a C1 byte-substring of it.

Claims

  • Breed: Keeshond (Dog)
  • Disorder:
  • Mode of inheritance: Multifactorial
  • Summary: see conotruncal heart malformations in the dog
  • Defect: yes

Evidence (references)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose.

  • 1995. Palliative treatment of tetralogy of fallot in a dog using a ptfe (polytetrafluorethylene) vascular graft [German]. Schweizer Archiv fur Tierheilkunde — PubMed:PMID7494990 — OMIA Phene_Article / Article
  • 1997. Retrospective study of congenital heart defects in 151 dogs. Journal of Small Animal Practice — PubMed:PMID9097239 — OMIA Phene_Article / Article
  • 1998. Open-heart correction of tetralogy of fallot in an acyanotic dog. Journal of the American Veterinary Medical Association — OMIA Phene_Article / Article
  • 1999. Balloon dilation of right ventricular outflow tract in a dog with tetralogy of Fallot. Journal of Veterinary Medical Science — PubMed:PMID10535516 — OMIA Phene_Article / Article
  • 2001. Open surgical repair of tetralogy of Fallot in dogs. Journal of the American Veterinary Medical Association — PubMed:PMID11700706 — OMIA Phene_Article / Article
  • 2009. Genetic screening of the canine zinc finger protein multitype 2 (cZFPM2) gene in dogs with tetralogy of Fallot (TOF).. J Anim Breed Genet — PubMed:PMID19630881 | DOI:10.1111/j.1439-0388.2008.00776.x — OMIA Phene_Article / Article
  • 2016. Epidemiological, clinical, and echocardiographic features and survival times of dogs and cats with tetralogy of Fallot: 31 cases (2003-2014).. J Am Vet Med Assoc — PubMed:PMID27700266 | DOI:10.2460/javma.249.8.909 — OMIA Phene_Article / Article
  • 2024. Complex tetralogy of Fallot in an acyanotic adult dog.. CASE (Phila) — PubMed:PMID38524971 | DOI:10.1016/j.case.2023.12.010 — OMIA Phene_Article / Article

Comparative medicine (human OMIM)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. Links this animal disorder to its human OMIM entry for comparative/translational context.

  • OMIM:187500 (type: trait) — OMIA Group_OMIM (via OMIA_ID)
  • OMIM:187501 (type: trait) — OMIA Group_OMIM (via OMIA_ID)
  • OMIM:239711 (type: trait) — OMIA Group_OMIM (via OMIA_ID)

Evidence (references)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose.

  • 1995. Palliative treatment of tetralogy of fallot in a dog using a ptfe (polytetrafluorethylene) vascular graft [German]. Schweizer Archiv fur Tierheilkunde — PubMed:PMID7494990 — OMIA Phene_Article / Article
  • 1997. Retrospective study of congenital heart defects in 151 dogs. Journal of Small Animal Practice — PubMed:PMID9097239 — OMIA Phene_Article / Article
  • 1998. Open-heart correction of tetralogy of fallot in an acyanotic dog. Journal of the American Veterinary Medical Association — OMIA Phene_Article / Article
  • 1999. Balloon dilation of right ventricular outflow tract in a dog with tetralogy of Fallot. Journal of Veterinary Medical Science — PubMed:PMID10535516 — OMIA Phene_Article / Article
  • 2001. Open surgical repair of tetralogy of Fallot in dogs. Journal of the American Veterinary Medical Association — PubMed:PMID11700706 — OMIA Phene_Article / Article
  • 2009. Genetic screening of the canine zinc finger protein multitype 2 (cZFPM2) gene in dogs with tetralogy of Fallot (TOF). J Anim Breed Genet — PubMed:PMID19630881 | DOI:10.1111/j.1439-0388.2008.00776.x — OMIA Phene_Article / Article
  • 2016. Epidemiological, clinical, and echocardiographic features and survival times of dogs and cats with tetralogy of Fallot: 31 cases (2003-2014). J Am Vet Med Assoc — PubMed:PMID27700266 | DOI:10.2460/javma.249.8.909 — OMIA Phene_Article / Article
  • 2024. Complex tetralogy of Fallot in an acyanotic adult dog. CASE (Phila) — PubMed:PMID38524971 | DOI:10.1016/j.case.2023.12.010 — OMIA Phene_Article / Article

Comparative medicine (human OMIM)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. Links this animal disorder to its human OMIM entry for comparative/translational context.

  • OMIM:187500 (type: trait) — OMIA Group_OMIM (via OMIA_ID)
  • OMIM:187501 (type: trait) — OMIA Group_OMIM (via OMIA_ID)
  • OMIM:239711 (type: trait) — OMIA Group_OMIM (via OMIA_ID)

Evidence (references)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

  • 1995. Palliative treatment of tetralogy of fallot in a dog using a ptfe (polytetrafluorethylene) vascular graft [German]. Schweizer Archiv fur Tierheilkunde — PubMed:PMID7494990 — OMIA Phene_Article / Article
  • 1997. Retrospective study of congenital heart defects in 151 dogs. Journal of Small Animal Practice — PubMed:PMID9097239 — OMIA Phene_Article / Article
  • 1998. Open-heart correction of tetralogy of fallot in an acyanotic dog. Journal of the American Veterinary Medical Association — OMIA Phene_Article / Article
  • 1999. Balloon dilation of right ventricular outflow tract in a dog with tetralogy of Fallot. Journal of Veterinary Medical Science — PubMed:PMID10535516 — OMIA Phene_Article / Article
  • 2001. Open surgical repair of tetralogy of Fallot in dogs. Journal of the American Veterinary Medical Association — PubMed:PMID11700706 — OMIA Phene_Article / Article
  • 2009. Genetic screening of the canine zinc finger protein multitype 2 (cZFPM2) gene in dogs with tetralogy of Fallot (TOF). J Anim Breed Genet — PubMed:PMID19630881 | DOI:10.1111/j.1439-0388.2008.00776.x — OMIA Phene_Article / Article
  • 2016. Epidemiological, clinical, and echocardiographic features and survival times of dogs and cats with tetralogy of Fallot: 31 cases (2003-2014). J Am Vet Med Assoc — PubMed:PMID27700266 | DOI:10.2460/javma.249.8.909 — OMIA Phene_Article / Article
  • 2024. Complex tetralogy of Fallot in an acyanotic adult dog. CASE (Phila) — PubMed:PMID38524971 | DOI:10.1016/j.case.2023.12.010 — OMIA Phene_Article / Article

Comparative medicine (human OMIM)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

  • OMIM:187500 (type: trait) — OMIA Group_OMIM (via OMIA_ID)
  • OMIM:187501 (type: trait) — OMIA Group_OMIM (via OMIA_ID)
  • OMIM:239711 (type: trait) — OMIA Group_OMIM (via OMIA_ID)

verification_derived: method: derived_from_dataset source: "OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM" note: "Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose."

Evidence (references)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

  • 1995. Palliative treatment of tetralogy of fallot in a dog using a ptfe (polytetrafluorethylene) vascular graft [German]. Schweizer Archiv fur Tierheilkunde — PubMed:PMID7494990 — OMIA Phene_Article / Article
  • 1997. Retrospective study of congenital heart defects in 151 dogs. Journal of Small Animal Practice — PubMed:PMID9097239 — OMIA Phene_Article / Article
  • 1998. Open-heart correction of tetralogy of fallot in an acyanotic dog. Journal of the American Veterinary Medical Association — OMIA Phene_Article / Article
  • 1999. Balloon dilation of right ventricular outflow tract in a dog with tetralogy of Fallot. Journal of Veterinary Medical Science — PubMed:PMID10535516 — OMIA Phene_Article / Article
  • 2001. Open surgical repair of tetralogy of Fallot in dogs. Journal of the American Veterinary Medical Association — PubMed:PMID11700706 — OMIA Phene_Article / Article
  • 2009. Genetic screening of the canine zinc finger protein multitype 2 (cZFPM2) gene in dogs with tetralogy of Fallot (TOF). J Anim Breed Genet — PubMed:PMID19630881 | DOI:10.1111/j.1439-0388.2008.00776.x — OMIA Phene_Article / Article
  • 2016. Epidemiological, clinical, and echocardiographic features and survival times of dogs and cats with tetralogy of Fallot: 31 cases (2003-2014). J Am Vet Med Assoc — PubMed:PMID27700266 | DOI:10.2460/javma.249.8.909 — OMIA Phene_Article / Article
  • 2024. Complex tetralogy of Fallot in an acyanotic adult dog. CASE (Phila) — PubMed:PMID38524971 | DOI:10.1016/j.case.2023.12.010 — OMIA Phene_Article / Article

Comparative medicine (human OMIM)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

  • OMIM:187500 (type: trait) — OMIA Group_OMIM (via OMIA_ID)
  • OMIM:187501 (type: trait) — OMIA Group_OMIM (via OMIA_ID)
  • OMIM:239711 (type: trait) — OMIA Group_OMIM (via OMIA_ID)

verification_derived: method: derived_from_dataset source: "OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM" note: "Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose."

Evidence (references)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

  • 1995. Palliative treatment of tetralogy of fallot in a dog using a ptfe (polytetrafluorethylene) vascular graft [German]. Schweizer Archiv fur Tierheilkunde — PubMed:PMID7494990 — OMIA Phene_Article / Article
  • 1997. Retrospective study of congenital heart defects in 151 dogs. Journal of Small Animal Practice — PubMed:PMID9097239 — OMIA Phene_Article / Article
  • 1998. Open-heart correction of tetralogy of fallot in an acyanotic dog. Journal of the American Veterinary Medical Association — OMIA Phene_Article / Article
  • 1999. Balloon dilation of right ventricular outflow tract in a dog with tetralogy of Fallot. Journal of Veterinary Medical Science — PubMed:PMID10535516 — OMIA Phene_Article / Article
  • 2001. Open surgical repair of tetralogy of Fallot in dogs. Journal of the American Veterinary Medical Association — PubMed:PMID11700706 — OMIA Phene_Article / Article
  • 2009. Genetic screening of the canine zinc finger protein multitype 2 (cZFPM2) gene in dogs with tetralogy of Fallot (TOF). J Anim Breed Genet — PubMed:PMID19630881 | DOI:10.1111/j.1439-0388.2008.00776.x — OMIA Phene_Article / Article
  • 2016. Epidemiological, clinical, and echocardiographic features and survival times of dogs and cats with tetralogy of Fallot: 31 cases (2003-2014). J Am Vet Med Assoc — PubMed:PMID27700266 | DOI:10.2460/javma.249.8.909 — OMIA Phene_Article / Article
  • 2024. Complex tetralogy of Fallot in an acyanotic adult dog. CASE (Phila) — PubMed:PMID38524971 | DOI:10.1016/j.case.2023.12.010 — OMIA Phene_Article / Article

Comparative medicine (human OMIM)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

  • OMIM:187500 (type: trait) — OMIA Group_OMIM (via OMIA_ID)
  • OMIM:187501 (type: trait) — OMIA Group_OMIM (via OMIA_ID)
  • OMIM:239711 (type: trait) — OMIA Group_OMIM (via OMIA_ID)

verification_derived: method: derived_from_dataset source: "OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM" note: "Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose."

Sources

Keeshond — Tetralogy of Fallot (hereditary; OMIA-verified breed predisposition)
companion-breed-healthPMID 7494990

Machine access

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