--- license: permission_granted topic_id: companion_breed_health_devon_rex_devon_rex_cat category: companion-breed-health title: "Devon Rex — Devon rex (hereditary; OMIA-verified breed predisposition)" lang: en source: "OMIA (Online Mendelian Inheritance in Animals, University of Sydney) breed-specific hereditary-disorder record, saved verbatim to source_file; C1 substring-verified. Pulled 2026-08-02 from local OMIA database dump." source_file: pdf-raw/breed-health/devon_rex_devon_rex_3107.txt date_parsed: 2026-08-02 tokens_estimated: 80 verification: method: substring_match claims: 5 passed: 5 date: 2026-08-02 recovered: false path: companion-breed-health/companion_breed_health_devon_rex_devon_rex_cat/01_companion_breed_health_devon_rex_devon_rex_cat.md source_document: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" citation: authority: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" title: "Devon Rex — Devon rex (hereditary; OMIA-verified breed predisposition)" url: "https://omia.org/OMIA001581/9685/" retrieved: "2026-08-02" ref: "OMIA breed-specific hereditary-disorder records (omia.org), derived from local OMIA database dump; dataset: https://doi.org/10.25910/2AMR-PV70" doc_type: "academic animal-genetics database (breed-specific disorder entries)" needs_review: false
Devon Rex — Devon rex (hereditary; OMIA-verified breed predisposition)
Source: first-hand OMIA (University of Sydney) breed-specific hereditary-disorder record, saved verbatim to source_file; every claim below is a C1 byte-substring of it.
Claims
Breed: Devon Rex (Cat)Disorder: Devon rexMode of inheritance: Autosomal recessiveSummary: see also a href=../../../../../../OMIA001712/9685/OMIA:001712-9685/a : Curly coat, Selkirk rex in Felis catus (domestic cat)Defect: no
Associated gene(s)
Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.
- Gene: Entrez Gene ID 5778227 (no symbol in OMIA GeneSynonym) — OMIA Phene_Gene
- OMIA molecular-genetics note: Gandolfi et al. (2010) showed that the Devon rex mutation and the Sphynx hairless mutation (<a href="../../../../../../OMIA001583/9685/">OMIA:001583-9685</a>) are both due to mutations in the KRT71 gene which encodes keratin 71: "An 81-bp deletion (c.1108-4_1184del), including the last 4 bp of intron 6 and the first 77 bp of exon 7, followed by a 8-bp insertion (c.1184_1185insAGTTGGAG) and a base …
Evidence (references)
Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.
- 1969. Devon rex - a third rexoid coat mutant in the cat. Genetica — OMIA Phene_Article / Article
- 2010. The naked truth: Sphynx and Devon Rex cat breed mutations in KRT71. Mamm Genome — PubMed:PMID20953787 | DOI:10.1007/s00335-010-9290-6 — OMIA Phene_Article / Article
- 2022. Genetic epidemiology of blood type, disease and trait variants, and genome-wide genetic diversity in over 11,000 domestic cats. PLoS Genet — PubMed:PMID35709088 | DOI:10.1371/journal.pgen.1009804 — OMIA Phene_Article / Article
Comparative medicine (human OMIM)
Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.
- OMIM:608245 (type: gene) — OMIA Group_OMIM (via OMIA_ID)
- OMIM:615896 (type: trait) — OMIA Group_OMIM (via OMIA_ID)
verification_derived: method: derived_from_dataset source: "OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM" note: "Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose."