Megestrol — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Megestrol is a active ingredient.
Total reports
Megestrol: 76
Reports by species (top entries)
- Cat 62
- Dog 13
- Other 1
Top reported reactions (VEDDRA terms, top entries)
- Diabetes mellitus 16
- Polydipsia 11
- Polyuria 9
- Death by euthanasia 8
- Diabetes 8
- Mammary gland neoplasm NOS 7
- Mammary hyperplasia 7
- Depression 6
- Glucosuria 6
- Hyperglycaemia 6
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b22.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).