{"topic_id":"ade_megestrol_adverse_events","category":"ade","context":"---\ntopic_id: ade_megestrol_adverse_events\ncategory: ade\ntitle: \"FDA ADE reports for Megestrol (active ingredient) — total reports, species & reaction breakdown\"\nlang: en\nsource: \"openFDA animalandveterinary/event.json (FDA CVM adverse event reports), pulled 2026-07-22\"\nsource_file: pdf-raw/ade/ade_active_ingredients_2026-07-22_b22.json\ndate_parsed: 2026-07-22\ntokens_estimated: 344\nverification:\n  method: substring_match\n  claims: 28\n  passed: 28\n  date: 2026-07-22\n---\n\n# Megestrol — FDA Animal & Veterinary Adverse Event (ADE) Reports\n\nSource: openFDA `animalandveterinary/event.json`, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Megestrol is a active ingredient.\n\n## Total reports\nMegestrol: 76\n\n## Reports by species (top entries)\n- Cat 62\n- Dog 13\n- Other 1\n\n## Top reported reactions (VEDDRA terms, top entries)\n- Diabetes mellitus 16\n- Polydipsia 11\n- Polyuria 9\n- Death by euthanasia 8\n- Diabetes 8\n- Mammary gland neoplasm NOS 7\n- Mammary hyperplasia 7\n- Depression 6\n- Glucosuria 6\n- Hyperglycaemia 6\n\nSource JSON: `pdf-raw/ade/ade_active_ingredients_2026-07-22_b22.json` (openFDA animalandveterinary/event.json, pulled 2026-07-22).\n","sources":[],"tokens_estimated":227,"generated_at":null,"tip":"Use /api/v1/topics to discover more topics. /api/v1/nutrient for precise single-point queries. /api/v1/cross_compare for 2-3 standard comparisons."}