Itraconazole — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-21. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Itraconazole is a veterinary active ingredient.
Total reports
Itraconazole: 580
Reports by species (top entries)
- Cat 436
- Dog 46
- Other Birds 3
- Human 2
- Goat 1
- Monkey 1
Top reported reactions (VEDDRA terms, top entries)
- Lack of efficacy - NOS 102
- Vomiting 88
- Lethargy (see also Central nervous system depression in 'Neurological') 64
- Elevated alanine aminotransferase (ALT) 60
- Not eating 60
- Weight loss 58
- Decreased appetite 47
- Elevated total bilirubin 45
- Elevated liver enzymes 41
- Diarrhoea 37
"Lack of efficacy" terms denote product-performance reports, not adverse reactions.
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-21.json (openFDA animalandveterinary/event.json, pulled 2026-07-21).