{"topic_id":"ade_itraconazole_adverse_events","category":"ade","context":"---\ntopic_id: ade_itraconazole\ncategory: ade\ntitle: \"FDA ADE reports for Itraconazole — total reports, species & reaction breakdown\"\nlang: en\nsource: \"openFDA animalandveterinary/event.json (FDA CVM adverse event reports), pulled 2026-07-21\"\nsource_file: pdf-raw/ade/ade_active_ingredients_2026-07-21.json\ndate_parsed: 2026-07-21\ntokens_estimated: 200\nverification:\n  method: substring_match\n  claims: 17\n  passed: 17\n  date: 2026-07-21\n---\n\n# Itraconazole — FDA Animal & Veterinary Adverse Event (ADE) Reports\n\nSource: openFDA `animalandveterinary/event.json`, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-21. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Itraconazole is a veterinary active ingredient.\n\n## Total reports\nItraconazole: 580\n\n## Reports by species (top entries)\n- Cat 436\n- Dog 46\n- Other Birds 3\n- Human 2\n- Goat 1\n- Monkey 1\n\n## Top reported reactions (VEDDRA terms, top entries)\n- Lack of efficacy - NOS 102\n- Vomiting 88\n- Lethargy (see also Central nervous system depression in 'Neurological') 64\n- Elevated alanine aminotransferase (ALT) 60\n- Not eating 60\n- Weight loss 58\n- Decreased appetite 47\n- Elevated total bilirubin 45\n- Elevated liver enzymes 41\n- Diarrhoea 37\n\n\"Lack of efficacy\" terms denote product-performance reports, not adverse reactions.\n\nSource JSON: `pdf-raw/ade/ade_active_ingredients_2026-07-21.json` (openFDA animalandveterinary/event.json, pulled 2026-07-21).\n","sources":[],"tokens_estimated":200,"generated_at":null,"tip":"Use /api/v1/topics to discover more topics. /api/v1/nutrient for precise single-point queries. /api/v1/cross_compare for 2-3 standard comparisons."}