Eprinomectin — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Eprinomectin is a macrocyclic lactone endectocide (flea/tick/heartworm).
Total reports
Eprinomectin: 5251
Reports by species (top entries)
- Cat 3498
- Cattle 1054
- Human 160
- Dog 97
- Goat 7
- Horse 7
Top reported reactions (VEDDRA terms, top entries)
- Vomiting 488
- Lethargy (see also Central nervous system depression in Neurological) 474
- Hypersalivation 397
- Death 395
- Accidental exposure 351
- Foaming at the mouth 310
- Application site hair loss 298
- Ataxia 264
- Drooling 248
- Lack of efficacy (endoparasite) - tapeworm 217
"Lack of efficacy" terms denote product-performance reports, not adverse reactions.
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b8.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).