{"topic_id":"ade_eprinomectin_adverse_events","category":"ade","context":"---\ntopic_id: ade_eprinomectin_adverse_events\ncategory: ade\ntitle: \"FDA ADE reports for Eprinomectin (macrocyclic lactone endectocide (flea/tick/heartworm)) — total reports, species & reaction breakdown\"\nlang: en\nsource: \"openFDA animalandveterinary/event.json (FDA CVM adverse event reports), pulled 2026-07-22\"\nsource_file: pdf-raw/ade/ade_active_ingredients_2026-07-22_b8.json\ndate_parsed: 2026-07-22\ntokens_estimated: 201\nverification:\n  method: substring_match\n  claims: 34\n  passed: 34\n  date: 2026-07-22\n---\n\n# Eprinomectin — FDA Animal & Veterinary Adverse Event (ADE) Reports\n\nSource: openFDA `animalandveterinary/event.json`, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Eprinomectin is a macrocyclic lactone endectocide (flea/tick/heartworm).\n\n## Total reports\nEprinomectin: 5251\n\n## Reports by species (top entries)\n- Cat 3498\n- Cattle 1054\n- Human 160\n- Dog 97\n- Goat 7\n- Horse 7\n\n## Top reported reactions (VEDDRA terms, top entries)\n- Vomiting 488\n- Lethargy (see also Central nervous system depression in Neurological) 474\n- Hypersalivation 397\n- Death 395\n- Accidental exposure 351\n- Foaming at the mouth 310\n- Application site hair loss 298\n- Ataxia 264\n- Drooling 248\n- Lack of efficacy (endoparasite) - tapeworm 217\n\n\"Lack of efficacy\" terms denote product-performance reports, not adverse reactions.\n\nSource JSON: `pdf-raw/ade/ade_active_ingredients_2026-07-22_b8.json` (openFDA animalandveterinary/event.json, pulled 2026-07-22).\n","sources":[],"tokens_estimated":274,"generated_at":null,"tip":"Use /api/v1/topics to discover more topics. /api/v1/nutrient for precise single-point queries. /api/v1/cross_compare for 2-3 standard comparisons."}