Doramectin — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Doramectin is a macrocyclic lactone endectocide (parasite control).
Total reports
Doramectin: 4523
Reports by species (top entries)
- Cattle 3085
- Human 281
- Pig 137
- Dog 103
- Cat 27
- Goat 24
Top reported reactions (VEDDRA terms, top entries)
- Lack of efficacy (ectoparasite) - lice 1086
- Pruritus 548
- Death 457
- Alopecia NOS 407
- INEFFECTIVE, LICE BITING 372
- Accidental exposure 292
- Lack of efficacy (lice) 277
- Caps, Abnormal 268
- Unclassifiable adverse event 231
- Vials, Leaking 199
"Lack of efficacy" terms denote product-performance reports, not adverse reactions.
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b8.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).