FDA ADE reports for Dexmedetomidine Hydrochloride (alpha-2 agonist sedative / analgesic) — total reports, species & reaction breakdown

ade_dexmedetomidine_hydrochloride_adverse_events

ade en 2026-07-22

Dexmedetomidine Hydrochloride — FDA Animal & Veterinary Adverse Event (ADE) Reports

Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Dexmedetomidine Hydrochloride is a alpha-2 agonist sedative / analgesic.

Total reports

Dexmedetomidine Hydrochloride: 5606

Reports by species (top entries)

Dog 3862
Cat 1412
Human 52
Rabbit 15
Other Mammals 12
Rat 7

Top reported reactions (VEDDRA terms, top entries)

INEFFECTIVE, SEDATION 907
Lack of efficacy - NOS 587
Bradycardia 567
Death 565
Vomiting 397
Cardiac arrest 368
Sedation prolonged 251
Lethargy (see also Central nervous system depression in 'Neurological') 249
Hypersalivation 215
Sedation 211

"Lack of efficacy" terms denote product-performance reports, not adverse reactions.

Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b8.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).

Sources

openFDA animalandveterinary/event.json (FDA CVM ADE), pulled 2026-07-22

Machine access

AI agents: this page mirrors GET /api/v1/llm_context?topic=ade_dexmedetomidine_hydrochloride_adverse_events (max 500 tokens, whitelisted). Rate limit 60 req/min for recognized AI crawlers.

Raw JSON ↗ llm.txt OpenAPI