{"topic_id":"ade_dexmedetomidine_hydrochloride_adverse_events","category":"ade","context":"---\ntopic_id: ade_dexmedetomidine_hydrochloride_adverse_events\ncategory: ade\ntitle: \"FDA ADE reports for Dexmedetomidine Hydrochloride (alpha-2 agonist sedative / analgesic) — total reports, species & reaction breakdown\"\nlang: en\nsource: \"openFDA animalandveterinary/event.json (FDA CVM adverse event reports), pulled 2026-07-22\"\nsource_file: pdf-raw/ade/ade_active_ingredients_2026-07-22_b8.json\ndate_parsed: 2026-07-22\ntokens_estimated: 201\nverification:\n  method: substring_match\n  claims: 34\n  passed: 34\n  date: 2026-07-22\n---\n\n# Dexmedetomidine Hydrochloride — FDA Animal & Veterinary Adverse Event (ADE) Reports\n\nSource: openFDA `animalandveterinary/event.json`, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Dexmedetomidine Hydrochloride is a alpha-2 agonist sedative / analgesic.\n\n## Total reports\nDexmedetomidine Hydrochloride: 5606\n\n## Reports by species (top entries)\n- Dog 3862\n- Cat 1412\n- Human 52\n- Rabbit 15\n- Other Mammals 12\n- Rat 7\n\n## Top reported reactions (VEDDRA terms, top entries)\n- INEFFECTIVE, SEDATION 907\n- Lack of efficacy - NOS 587\n- Bradycardia 567\n- Death 565\n- Vomiting 397\n- Cardiac arrest 368\n- Sedation prolonged 251\n- Lethargy (see also Central nervous system depression in 'Neurological') 249\n- Hypersalivation 215\n- Sedation 211\n\n\"Lack of efficacy\" terms denote product-performance reports, not adverse reactions.\n\nSource JSON: `pdf-raw/ade/ade_active_ingredients_2026-07-22_b8.json` (openFDA animalandveterinary/event.json, pulled 2026-07-22).\n","sources":[],"tokens_estimated":276,"generated_at":null,"tip":"Use /api/v1/topics to discover more topics. /api/v1/nutrient for precise single-point queries. /api/v1/cross_compare for 2-3 standard comparisons."}