Acetylcysteine — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Acetylcysteine is a active ingredient.
Total reports
Acetylcysteine: 47
Reports by species (top entries)
- Dog 41
- Cat 4
- Horse 1
Top reported reactions (VEDDRA terms, top entries)
- Elevated alanine aminotransferase (ALT) 21
- Elevated total bilirubin 21
- Abnormal ultrasound finding 16
- Death by euthanasia 14
- Lethargy (see also Central nervous system depression in Neurological) 13
- Vomiting 13
- Elevated serum alkaline phosphatase (ALP) 12
- Hypokalaemia 12
- Death 11
- Icterus 11
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b25.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).