{"topic_id":"ade_acetylcysteine_adverse_events","category":"ade","context":"---\ntopic_id: ade_acetylcysteine_adverse_events\ncategory: ade\ntitle: \"FDA ADE reports for Acetylcysteine (active ingredient) — total reports, species & reaction breakdown\"\nlang: en\nsource: \"openFDA animalandveterinary/event.json (FDA CVM adverse event reports), pulled 2026-07-22\"\nsource_file: pdf-raw/ade/ade_active_ingredients_2026-07-22_b25.json\ndate_parsed: 2026-07-22\ntokens_estimated: 344\nverification:\n  method: substring_match\n  claims: 28\n  passed: 28\n  date: 2026-07-22\n---\n\n# Acetylcysteine — FDA Animal & Veterinary Adverse Event (ADE) Reports\n\nSource: openFDA `animalandveterinary/event.json`, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Acetylcysteine is a active ingredient.\n\n## Total reports\nAcetylcysteine: 47\n\n## Reports by species (top entries)\n- Dog 41\n- Cat 4\n- Horse 1\n\n## Top reported reactions (VEDDRA terms, top entries)\n- Elevated alanine aminotransferase (ALT) 21\n- Elevated total bilirubin 21\n- Abnormal ultrasound finding 16\n- Death by euthanasia 14\n- Lethargy (see also Central nervous system depression in Neurological) 13\n- Vomiting 13\n- Elevated serum alkaline phosphatase (ALP) 12\n- Hypokalaemia 12\n- Death 11\n- Icterus 11\n\nSource JSON: `pdf-raw/ade/ade_active_ingredients_2026-07-22_b25.json` (openFDA animalandveterinary/event.json, pulled 2026-07-22).\n","sources":[],"tokens_estimated":245,"generated_at":null,"tip":"Use /api/v1/topics to discover more topics. /api/v1/nutrient for precise single-point queries. /api/v1/cross_compare for 2-3 standard comparisons."}