EFSA FEEDAP — L-valine (C. glutamicum KCCM 80366, non-GM) for all animal species
Source: EFSA FEEDAP scientific opinion, EFSA Journal 2025;23(12):e9782 (DOI 10.2903/j.efsa.2025.9782), retrieved 2026-08-06 via Europe PMC OA full-text XML. Paraphrase of an EFSA opinion that the source XML tags CC-BY-ND; per project COPYRIGHT_POLICY only facts/numbers/proper-nouns are quoted verbatim, sentences rewritten.
Editorial context (read this before using the data point)
This is the EFSA FEEDAP jurisdiction on the amino-acid feed additive C. glutamicum KCCM 80366 — one of four amino-acid safety opinions in this batch. Read with the efsa nutrient endpoints and AAFCO/FEDIAF amino-acid provisions.
Key findings (paraphrase; numbers and proper nouns verbatim from source)
- L-valine is produced using the non-genetically modified *C. glutamicum* KCCM 80366; viable cells were not detected and the strain does not harbour any gene of concern.
- Its use in animal nutrition is considered safe for all animal species, the consumers and for the environment.
- For user safety it is not irritant to skin but is considered a skin and respiratory sensitiser (no conclusion on eye irritancy); inhalation and dermal exposure are a risk.
- It is an effective source of the essential amino acid L-valine for all animal species; to match non-ruminant efficacy in ruminants it should be protected from ruminal degradation.
Pet-food relevance
L-valine is an essential amino acid in cats and dogs. The unqualified 'safe for all animal species, consumers and environment' conclusion (non-GM strain, no gene of concern) is the headline; the user-sensitiser warning is the practical handling caveat. The ~1.1% unidentified fraction is the stated residual uncertainty.
Scope note / honest gap
Paraphrase of an EFSA opinion; source XML licence tag was CC-BY-ND, so this topic quotes only data points verbatim and rewrites prose. Full strain-characterisation and toxicity statistics are not reproduced.