EFSA FEEDAP — L-lysine sulfate (C. glutamicum KCCM 80368, GM) for all animal species
Source: EFSA FEEDAP scientific opinion, EFSA Journal 2026;24(3) (DOI 10.2903/j.efsa.2026.9922), retrieved 2026-08-06 via Europe PMC OA full-text XML. Paraphrase of an EFSA opinion that the source XML tags CC-BY-ND; per project COPYRIGHT_POLICY only facts/numbers/proper-nouns are quoted verbatim, sentences rewritten.
Editorial context (read this before using the data point)
This is the EFSA FEEDAP jurisdiction on the amino-acid feed additive C. glutamicum KCCM 80368 — one of four amino-acid safety opinions in this batch. Read with the efsa nutrient endpoints and AAFCO/FEDIAF amino-acid provisions.
Key findings (paraphrase; numbers and proper nouns verbatim from source)
- L-lysine sulfate is produced using the genetically modified strain *C. glutamicum* KCCM 80368; the additive was characterised up to 93.2% and the conclusions apply only to that manufacturing process.
- Viable cells were not detected; DNA from the strain is present but not considered of concern, so the GM strain raises no safety concern.
- Its use in animal nutrition is considered safe for the target animals, the consumer and the environment.
- For user safety it is not irritant to the skin (no conclusion on eye irritation) but should be considered a respiratory and skin sensitiser; inhalation and dermal exposure are a risk.
- It is an effective source of the essential amino acid L-lysine for all animal species; to match non-ruminant efficacy in ruminants it should be protected from ruminal degradation.
Pet-food relevance
L-lysine is an essential amino acid in cats and dogs. The positive overall safety conclusion (target animals, consumer, environment) and the user-sensitiser warning are the directly usable data points; the ~7% unidentified fraction (fermentation residues) is the stated residual uncertainty.
Scope note / honest gap
Paraphrase of an EFSA opinion; source XML licence tag was CC-BY-ND, so this topic quotes only data points verbatim and rewrites prose. Full sub-chronic and genotoxicity study details are not reproduced.