← All Topics / efsa

EFSA FEEDAP — L-lysine monohydrochloride (C. glutamicum CGMCC 23982) for all animal species: safe; irritant to skin/eyes, respiratory irritant (EFSA Journal 2026;24(4):e10033)

EFSA_FEEDAP_llysine_hcl_safety

efsa 460 tok en 2026-08-06

EFSA FEEDAP — L-lysine monohydrochloride (C. glutamicum CGMCC 23982) for all animal species

Source: EFSA FEEDAP scientific opinion, EFSA Journal 2026;24(4):e10033 (DOI 10.2903/j.efsa.2026.10033), retrieved 2026-08-06 via Europe PMC OA full-text XML. Paraphrase of an EFSA opinion that the source XML tags CC-BY-ND; per project COPYRIGHT_POLICY only facts/numbers/proper-nouns are quoted verbatim, sentences rewritten.

Editorial context (read this before using the data point)

This is the EFSA FEEDAP jurisdiction on the nutrient/additive L-lysine monohydrochloride (C. glutamicum CGMCC 23982) — one of five nutrient-safety opinions in this final batch (Task L). Read with the efsa nutrient endpoints and AAFCO/FEDIAF provisions for the same nutrient.

Key findings (paraphrase; numbers and proper nouns verbatim from source)

  • Production strain C. glutamicum CGMCC 23982 raises no safety concern.
  • The additive is safe for the target species when supplemented in appropriate amounts and safe for consumers and the environment.
  • User safety — a clear warning: L-lysine monohydrochloride is irritant to the skin, irritant to the eyes, and a respiratory irritant; exposure by any route is a risk.
  • It is an effective source of L-lysine for all non-ruminant species; ruminants need protection from ruminal degradation.

Pet-food relevance

L-lysine is an essential amino acid, often first-limiting in cat and dog diets. This opinion (monohydrochloride salt) adds the explicit user-irritancy warning absent from the lysine-sulfate opinion; both safe-for-species conclusions hold.

Scope note / honest gap

Paraphrase of an EFSA opinion; source XML licence tag was CC-BY-ND, so this topic quotes only data points verbatim and rewrites prose. Full strain-characterisation and tolerance statistics are not reproduced.

Sources

EFSA FEEDAP — L-lysine monohydrochloride (C. glutamicum CGMCC 23982) for all animal species: safe; irritant to skin/eyes, respiratory irritant (EFSA Journal 2026;24(4):e10033)
Source document: EFSA FEEDAP — L-lysine monohydrochloride (C. glutamicum CGMCC 23982) for all animal species: safe; irritant to skin/eyes, respiratory irritant (EFSA Journal 2026;24(4):e10033)
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)EFSA Journal 2026;24(4):e10033retrieved 2026-08-06

Verification file: pdf-raw/efsa_l/lysineHCl_b6.xml