{"topic_id":"EFSA_FEEDAP_llysine_hcl_safety","category":"efsa","context":"---\ntopic_id: EFSA_FEEDAP_llysine_hcl_safety\ncategory: efsa\ntitle: \"EFSA FEEDAP — L-lysine monohydrochloride (C. glutamicum CGMCC 23982) for all animal species: safe; irritant to skin/eyes, respiratory irritant (EFSA Journal 2026;24(4):e10033)\"\nlang: en\nsource: \"EFSA FEEDAP scientific opinion, EFSA Journal 2026;24(4):e10033 (DOI 10.2903/j.efsa.2026.10033)\"\nsource_file: pdf-raw/efsa_l/lysineHCl_b6.xml\nsource_type: journal_article\ndate_parsed: 2026-08-06\ntokens_estimated: 460\nverified: true\nverification:\n  method: paraphrase\n  claims: 6\n  passed: 6\n  date: 2026-08-06\nsource_document: \"EFSA FEEDAP — L-lysine monohydrochloride (C. glutamicum CGMCC 23982) for all animal species: safe; irritant to skin/eyes, respiratory irritant (EFSA Journal 2026;24(4):e10033)\"\ncitation:\n  authority: \"EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)\"\n  title: \"EFSA FEEDAP — L-lysine monohydrochloride (C. glutamicum CGMCC 23982) for all animal species: safe; irritant to skin/eyes, respiratory irritant (EFSA Journal 2026;24(4):e10033)\"\n  url: \"https://doi.org/10.2903/j.efsa.2026.10033\"\n  retrieved: \"2026-08-06\"\n  ref: \"EFSA Journal 2026;24(4):e10033\"\n  doc_type: \"EFSA scientific opinion (Europe PMC OA full-text XML)\"\n  needs_review: false\nauthority_tier: T1\nauthority_tier_basis: \"T1:eu-body\"\nauthority_tier_date: 2026-08-06\n---\n# EFSA FEEDAP — L-lysine monohydrochloride (C. glutamicum CGMCC 23982) for all animal species\n\nSource: EFSA FEEDAP scientific opinion, EFSA Journal 2026;24(4):e10033 (DOI 10.2903/j.efsa.2026.10033), retrieved 2026-08-06 via Europe PMC OA full-text XML. Paraphrase of an EFSA opinion that the source XML tags CC-BY-ND; per project COPYRIGHT_POLICY only facts/numbers/proper-nouns are quoted verbatim, sentences rewritten.\n\n## Editorial context (read this before using the data point)\n\nThis is the **EFSA FEEDAP** jurisdiction on the nutrient/additive **L-lysine monohydrochloride (C. glutamicum CGMCC 23982)** — one of five nutrient-safety opinions in this final batch (Task L). Read with the `efsa` nutrient endpoints and AAFCO/FEDIAF provisions for the same nutrient.\n\n## Key findings (paraphrase; numbers and proper nouns verbatim from source)\n\n- Production strain **C. glutamicum CGMCC 23982** raises no safety concern.\n- The additive is **safe for the target species when supplemented in appropriate amounts** and **safe for consumers and the environment**.\n- **User safety — a clear warning**: L-lysine monohydrochloride is **irritant to the skin, irritant to the eyes, and a respiratory irritant**; exposure by any route is a risk.\n- It is an **effective source of L-lysine for all non-ruminant species**; ruminants need protection from ruminal degradation.\n\n## Pet-food relevance\n\nL-lysine is an essential amino acid, often first-limiting in cat and dog diets. This opinion (monohydrochloride salt) adds the explicit user-irritancy warning absent from the lysine-sulfate opinion; both safe-for-species conclusions hold.\n\n## Scope note / honest gap\n\nParaphrase of an EFSA opinion; source XML licence tag was CC-BY-ND, so this topic quotes only data points verbatim and rewrites prose. Full strain-characterisation and tolerance statistics are not reproduced.\n","sources":["OFT3 — EFSA FEEDAP — L-lysine monohydrochloride (C. glutamicum CGMCC 23982) for all animal species: safe; irritant to skin/eyes, respiratory irritant (EFSA Journal 2026;24(4):e10033) (retrieved 2026-08-06)"],"source":{"authority":"OFT3","title":"EFSA FEEDAP — L-lysine monohydrochloride (C. glutamicum CGMCC 23982) for all animal species: safe; irritant to skin/eyes, respiratory irritant (EFSA Journal 2026;24(4):e10033)","url":"https://doi.org/10.2903/j.efsa.2026.10033","retrieved":"2026-08-06","ref":"","doc_type":"official PDF","source_document":"EFSA FEEDAP — L-lysine monohydrochloride (C. glutamicum CGMCC 23982) for all animal species: safe; irritant to skin/eyes, respiratory irritant (EFSA Journal 2026;24(4):e10033)","verification_file":"pdf-raw/efsa_l/lysineHCl_b6.xml"},"source_document":"EFSA FEEDAP — L-lysine monohydrochloride (C. glutamicum CGMCC 23982) for all animal species: safe; irritant to skin/eyes, respiratory irritant (EFSA Journal 2026;24(4):e10033)","source_file":"pdf-raw/efsa_l/lysineHCl_b6.xml","trust":{"authority_tier":"T1","fidelity":"paraphrase","license":null,"display_grade":"C"},"tokens_estimated":460,"generated_at":null,"tip":"Use /api/v1/topics to discover more topics. /api/v1/nutrient for precise single-point queries. /api/v1/cross_compare for 2-3 standard comparisons."}