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EFSA FEEDAP — choline chloride renewal: safe for target species/consumer/environment; potential skin & respiratory sensitiser, 70% aq. non-irritant to eyes (EFSA Journal 2025;23(2))

EFSA_FEEDAP_choline_chloride_safety

efsa 440 tok en 2026-08-06

EFSA FEEDAP — choline chloride — renewal of authorisation

Source: EFSA FEEDAP scientific opinion, EFSA Journal 2025;23(2) (DOI 10.2903/j.efsa.2025.9264), retrieved 2026-08-06 via Europe PMC OA full-text XML. Paraphrase of an EFSA opinion that the source XML tags CC-BY-ND; per project COPYRIGHT_POLICY only facts/numbers/proper-nouns are quoted verbatim, sentences rewritten.

Editorial context (read this before using the data point)

This is the EFSA FEEDAP jurisdiction on the nutrient/additive choline chloride — one of four nutrient-safety opinions in this batch (Task L). Read with the efsa nutrient endpoints and AAFCO/FEDIAF provisions for the same nutrient.

Key findings (paraphrase; numbers and proper nouns verbatim from source)

  • This is a renewal-of-authorisation assessment of choline chloride.
  • Its use in animal nutrition remains safe for target species, consumers and the environment under approved conditions of use.
  • User safety: choline chloride should be considered a potential skin and respiratory sensitiser; any skin or respiratory exposure is a risk.
  • Aqueous solutions of up to 70% choline chloride are non-irritant to eyes, but no conclusion can be reached on eye irritation for more concentrated forms.

Pet-food relevance

Choline is an essential nutrient in cats and dogs (liver function, brain development, lipid transport). The confirmed 'remains safe' conclusion is the usable takeaway; the skin/respiratory-sensitiser warning is the practical handling caveat.

Scope note / honest gap

Paraphrase of an EFSA opinion; source XML licence tag was CC-BY-ND, so this topic quotes only data points verbatim and rewrites prose. Renewal opinion (efficacy not re-assessed); full characterisation statistics are not reproduced.

Sources

EFSA FEEDAP — choline chloride renewal: safe for target species/consumer/environment; potential skin & respiratory sensitiser, 70% aq. non-irritant to eyes (EFSA Journal 2025;23(2))
Source document: EFSA FEEDAP — choline chloride renewal: safe for target species/consumer/environment; potential skin & respiratory sensitiser, 70% aq. non-irritant to eyes (EFSA Journal 2025;23(2))
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)EFSA Journal 2025;23(2)retrieved 2026-08-06

Verification file: pdf-raw/efsa_l/choline_feed.xml