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Antibiotic (enteric dysbiosis / enterotoxemia) toxicity in rabbits — oral antibiotic contraindications

exotic_tox_rabbit_antibiotics

exotic-pet-toxicology en 2026-07-29

Antibiotic (enteric dysbiosis / enterotoxemia) toxicity in rabbits — oral antibiotic contraindications

Verbatim first-hand facts from The Merck Veterinary Manual (rabbit). All bullets are exact substrings of the cited source file and C1-substring verified. Focus: toxicosis and environmental hazards of the pet species.

Toxicology facts

  • Very few products are licensed for use in rabbits, leading to extra-label use of drug therapies approved for use in other species. Particular caution must be exercised in use of antibiotics that suppress normal GI microflora and result in enteric dysbiosis and/or enterotoxemia. This has been called “antibiotic toxicity.” Antibiotics contraindicated for oral administration in rabbits include but not limited to clindamycin, lincomycin, erythromycin, ampicillin, amoxicillin/clavulanic acid, and cephalosporins. The flea treatment fipronil is contraindicated in rabbits because of severe toxic reactions in some individuals.

Sources

Antibiotic (enteric dysbiosis / enterotoxemia) toxicity in rabbits — oral antibiotic contraindications
Source document: The Merck Veterinary Manual
The Merck Veterinary ManualMerckVetManual-rabbitretrieved 2026-07-29

Verification file: pdf-raw/exotic-toxicology/rabbit.txt