Evidence: feline hyperthyroidism: management with radioiodine, methimazole & surgery (peer-reviewed, Europe PMC)
Source: Europe PMC (Europe PubMed Central) REST search — first-hand peer-reviewed abstract records, pulled 2026-07-24. Query: (feline hyperthyroidism) AND (radioiodine OR methimazole OR thyroidectomy OR management OR treatment). The cluster returns 6 first-hand abstracts extracted below (verbatim sentences, each traceable by PMID).
Verified claims (verbatim, substring of saved source)
- PMID 41472095 — Hyperthyroidism is a common endocrine disorder in elderly cats, often leading to concurrent cardiac abnormalities.
- PMID 41566222 — ObjectivesThe aim of the present study was to report changes in serum creatinine and symmetric dimethylarginine (SDMA) concentrations after treatment of feline hyperthyroidism with anti thyroid medications and to compare these biomarkers at baseline between cats that were and were not azotaemic after treatment.MethodsIn this retrospective study, hyperthyroid cats that were euthyroid (total thyroxine [TT4] concentration 7-40 nmol/l) at 1 month (T1) and/or 2-9 months (T2) after treatment were identified and grouped by renal status defined by serum creatinine concentrations.
- PMID 41600691 — Companion animal endocrinology has benefited from international standardisation of disease terminology for diabetes mellitus, Cushing's syndrome, and hypoadrenocorticism through Project Agreeing Language in Veterinary Endocrinology (ALIVE).
- PMID 41472144 — An 8-year-old castrated male Pomeranian with a non-resectable functional thyroid carcinoma and concurrent myxomatous mitral valve disease was referred for radioactive-iodine therapy.
- PMID 42359893 — Objectives To determine the frequency and clinical significance of discordant serum symmetric dimethylarginine (SDMA) and creatinine concentrations relative to glomerular filtration rate (GFR) in mature and senior hyperthyroid cats treated with radioactive iodine (RAI).
- PMID 39724773 — Objective Many hyperthyroid cats (15% to 50%) have concurrent chronic kidney disease (CKD) that is "masked" and will not become azotemic until after treatment.
Studies (PMID / year / journal / title)
- PMID 41472095 (2025, Veterinary sciences) — Cardiac Abnormalities in Feline Hyperthyroidism.
- PMID 41566222 (2026, Journal of feline medicine and surgery) — Changes in serum symmetric dimethylarginine concentrations after treatment of feline hyperthyroidism with antithyroid medications.
- PMID 41600691 (2026, Veterinary sciences) — Agreeing Language in Veterinary Endocrinology (ALIVE): Hypothyroidism, Hyperthyroidism, (Euglycaemic) Diabetic Ketosis/Ketoacidosis, and Diabetic Remission-A Modified Delphi-Method-Based System to Create Consensus Definitions.
- PMID 41472144 (2025, Veterinary sciences) — Successful Long-Term Survival Following Thyroid Storm Induced by Radioactive Iodine Therapy in a Dog with Thyroid Carcinoma.
- PMID 42359893 (2026, Journal of feline medicine and surgery) — EXPRESS: Longitudinal evaluation of discordant symmetric dimethylarginine and creatinine as markers of glomerular filtration rate in radioiodine-treated hyperthyroid cats.
- PMID 39724773 (2025, Journal of the American Veterinary Medical Association) — Hyperthyroid cats that develop azotemia following successful radioiodine treatment have shorter survival times compared to cats that remain nonazotemic.
Source text: pdf-raw/evidence/pubmed_evidence_feline_hyperthyroidism_management_2026-07-24.txt (Europe PMC first-hand abstracts, pulled 2026-07-24).