Evidence: feline hyperthyroidism: management with radioiodine, methimazole & surgery (peer-reviewed, Europe PMC)
Source: Europe PMC (Europe PubMed Central) REST search — first-hand peer-reviewed abstract records, pulled 2026-07-24. Query: (feline hyperthyroidism) AND (radioiodine OR methimazole OR thyroidectomy OR management OR treatment). The cluster returns 10 first-hand abstracts extracted below (verbatim sentences, each traceable by PMID).
Verified claims (verbatim, substring of saved source)
- PMID 41472095 — Hyperthyroidism is a common endocrine disorder in elderly cats, often leading to concurrent cardiac abnormalities. *[CC BY — Open Access, verbatim with attribution.]*
- PMID 41566222 — ObjectivesThe aim of the present study was to report changes in serum creatinine and symmetric dimethylarginine (SDMA) concentrations after treatment of feline hyperthyroidism with anti thyroid medications and to compare these biomarkers at baseline between cats that were and were not azotaemic after treatment.MethodsIn this retrospective study, hyperthyroid cats that were euthyroid (total thyroxine [TT4] concentration 7-40 nmol/l) at 1 month (T1) and/or 2-9 months (T2) after treatment were identified and grouped by renal status defined by serum creatinine concentrations. *[CC BY — Open Access, verbatim with attribution.]*
- PMID 41600691 — Companion animal endocrinology has benefited from international standardisation of disease terminology for diabetes mellitus, Cushing's syndrome, and hypoadrenocorticism through Project Agreeing Language in Veterinary Endocrinology (ALIVE). *[CC BY — Open Access, verbatim with attribution.]*
- PMID 42359893 — *[Paraphrased derived summary — non-Open-Access source.]* A study assessed the frequency and clinical significance of discordant serum symmetric dimethylarginine (SDMA) and creatinine relative to glomerular filtration rate (GFR) in mature and senior hyperthyroid cats treated with radioactive iodine (RAI). (Source excerpt truncated at abstract opening.)
- PMID 39724773 — *[Paraphrased derived summary — non-Open-Access source.]* Many hyperthyroid cats (15%–50%) have concurrent chronic kidney disease (CKD) that is 'masked' and will not become azotemic until after hyperthyroidism treatment. (Source excerpt truncated at abstract opening.)
Studies (PMID / year / journal / title)
- PMID 41472095 (2025, Veterinary sciences) — Cardiac Abnormalities in Feline Hyperthyroidism. *[CC BY — Open Access, verbatim with attribution.]*
- PMID 41566222 (2026, Journal of feline medicine and surgery) — Changes in serum symmetric dimethylarginine concentrations after treatment of feline hyperthyroidism with antithyroid medications. *[CC BY — Open Access, verbatim with attribution.]*
- PMID 41600691 (2026, Veterinary sciences) — Agreeing Language in Veterinary Endocrinology (ALIVE): Hypothyroidism, Hyperthyroidism, (Euglycaemic) Diabetic Ketosis/Ketoacidosis, and Diabetic Remission-A Modified Delphi-Method-Based System to Create Consensus Definitions. *[CC BY — Open Access, verbatim with attribution.]*
- PMID 42359893 (2026, Journal of feline medicine and surgery) — *[Paraphrased derived summary — non-Open-Access source.]* A study assessed the frequency and clinical significance of discordant serum symmetric dimethylarginine (SDMA) and creatinine relative to glomerular filtration rate (GFR) in mature and senior hyperthyroid cats treated with radioactive iodine (RAI). (Source excerpt truncated at abstract opening.)
- PMID 39724773 (2025, Journal of the American Veterinary Medical Association) — *[Paraphrased derived summary — non-Open-Access source.]* Many hyperthyroid cats (15%–50%) have concurrent chronic kidney disease (CKD) that is 'masked' and will not become azotemic until after hyperthyroidism treatment. (Source excerpt truncated at abstract opening.)
Source text: pdf-raw/evidence/pubmed_evidence_feline_hyperthyroidism_management_2026-07-24.txt (Europe PMC first-hand abstracts, pulled 2026-07-24).
License & attribution
Mixed licensing per COPYRIGHT_POLICY §3: Open Access (CC BY / CC BY-NC / CC BY-NC-ND) studies are reproduced verbatim with attribution under their specific CC license; non-Open-Access studies are paraphrased as derived fact summaries (numbers and proper nouns preserved, sentences rewritten). Original records:
- https://pubmed.ncbi.nlm.nih.gov/41472095/
- https://pubmed.ncbi.nlm.nih.gov/41566222/
- https://pubmed.ncbi.nlm.nih.gov/41600691/
- https://pubmed.ncbi.nlm.nih.gov/42359893/
- https://pubmed.ncbi.nlm.nih.gov/39724773/
- https://pubmed.ncbi.nlm.nih.gov/41472095/
- https://pubmed.ncbi.nlm.nih.gov/41566222/
- https://pubmed.ncbi.nlm.nih.gov/41600691/
- https://pubmed.ncbi.nlm.nih.gov/42359893/
- https://pubmed.ncbi.nlm.nih.gov/39724773/
Cleaning removal log (2026-08-05, codebuddy)
PMID 41472144 — dog study (thyroid carcinoma in a dog treated with radioactive iodine), wrong species for a feline hyperthyroidism topic