evidence_feline_hepatic_lipidosis_diet
Source: first-hand peer-reviewed abstracts (Europe PMC / PubMed efetch), reproduced verbatim. Each claim below is a C1 substring of the cited source file.
Claims (C1 — verbatim substrings of source_file)
- PMID 42283012 — Multi-target synergistic mechanisms of flavonoid compounds from traditional Chinese medicine in non-alcoholic fatty liver disease: insights for human and veterinary medicine (Front Vet Sci, 2026). Abstract (opening): INTRODUCTION: Non-alcoholic fatty liver disease (NAFLD) is a prevalent chronic liver disorder characterized by dysregulated hepatic lipid metabolism, with a continuously rising global incidence and limited safe and effective therapeutic options. Importantly, NAFLD-like conditions, namely hepatic lipidosis or fatty liver syndrome, also prevail in veterinary clinical practice, affecting companion animals (obese cats and dogs) and livestock (periparturient dairy cows, fattening pigs, and broiler chickens). *[CC BY — Open Access, verbatim with attribution.]*
- PMID 42188883 — Evaluation of Serum Homocysteine and High-Sensitivity Cardiac Troponins in Cats with Hepatic Lipidosis: An Observational Clinical Study (Vet Sci, 2026). Abstract (opening): Feline hepatic lipidosis (FHL) is a life-threatening, common hepatobiliary disease characterized by massive triglyceride accumulation in the liver, often triggered by anorexia and negative energy balance in cats. This condition causes severe metabolic stress that may secondarily impact myocardial integrity. *[CC BY — Open Access, verbatim with attribution.]*
- PMID 42188039 — Lipidomic Signatures in Feline Disease: A PRISMA-Guided Systematic Review (Metabolites, 2026). Abstract (opening): enabling comprehensive characterisation of lipid species and their roles in health and disease. As regulators of membrane architecture, energy balance, inflammation, and cellular signalling, lipids offer a powerful framework for understanding metabolic dysfunction. *[CC BY — Open Access, verbatim with attribution.]*
- PMID 42022391 — From pathogenesis to prevention: an update on the management of obesity and its associated comorbidities in cats (Front Vet Sci, 2026). Abstract (opening): Overweight and obesity represent the most common nutritional disorder in domestic cats and constitute a significant global health issue. In this review, we synthesize current knowledge on the determinants, diagnosis, pathophysiology, complications, and comprehensive management of feline obesity. *[CC BY — Open Access, verbatim with attribution.]*
- PMID 41448592 — *[Paraphrased derived summary — non-Open-Access source.]* A case report of an 8-year-old spayed female domestic shorthair with one week of anorexia and lethargy, in which hepatic fine-needle aspiration showing numerous adipocytes confirmed hepatic lipidosis; the excerpt is cut off before the parenteral amino-acid/hyperammonemia management is detailed.
- PMID 41742558 — Preliminary metabolic characterization of hepatic lipidosis in cats using liquid chromatography-mass spectrometry and gas chromatography-mass spectrometry: pathway insights and candidate biomarkers (J Vet Intern Med, 2026). Abstract (opening): BACKGROUND: Feline hepatic lipidosis (FHL) lacks well-defined metabolic biomarkers and mechanistic understanding. HYPOTHESIS/OBJECTIVES: Clarify the metabolic biomarkers and mechanisms of FHL. *[CC BY — Open Access, verbatim with attribution.]*
Source: pdf-raw/evidence/europepmc_feline_hepatic_lipidosis_diet_2026-07-22.txt
License & attribution
Mixed licensing per COPYRIGHT_POLICY §3: Open Access (CC BY / CC BY-NC / CC BY-NC-ND) studies are reproduced verbatim with attribution under their specific CC license; non-Open-Access studies are paraphrased as derived fact summaries (numbers and proper nouns preserved, sentences rewritten). Original records:
- https://pubmed.ncbi.nlm.nih.gov/41448592/
- https://pubmed.ncbi.nlm.nih.gov/41742558/
- https://pubmed.ncbi.nlm.nih.gov/42022391/
- https://pubmed.ncbi.nlm.nih.gov/42188039/
- https://pubmed.ncbi.nlm.nih.gov/42188883/
- https://pubmed.ncbi.nlm.nih.gov/42283012/