Evidence: dietary management (taurine, sodium) of feline hypertrophic cardiomyopathy
Source: Europe PMC (Europe PubMed Central) REST search — first-hand peer-reviewed abstract records, pulled 2026-07-27. Query: hypertrophic cardiomyopathy cat diet. The cluster returns 1359 records in Europe PMC; 6 representative studies are extracted below. Abstract text is verbatim from source; each study is traceable by PMID.
Studies
- PMID 41779017 (2026, Epigenetics) — Transient elevation in cellular glucose uptake exacerbates pressure overload-induced cardiac hypertrophy and dysfunction... Clinically prior hyperglycemia may lead to long-lasting adverse cardiovascular effects, a process referred to as 'glycemic memory.' Epigenetic modifications, specifically DNA methylation changes, may play a key role in this phenomenon. This study investigated if prior high glucose delivery to cardiomyocytes, led to worsened cardiovascular effects upon pressure overload and to a
- PMID 41969281 (2026, Non-coding RNA research) — Transfer RNA-derived small RNAs in cardiovascular diseases: Progress and perspectives... tRNA-derived small RNAs (tsRNAs) are a class of noncoding RNAs (ncRNAs) generated via the site-specific enzymatic cleavage of mature or precursor tRNAs. They are ubiquitously expressed across diverse species and are detectable in numerous cell lineages and extracellular fluids like blood and serum. They regulate gene expression at multiple levels and are functionally implicated
- PMID 42292690 (2026, American heart journal plus : cardiology research and practice) — ACOT1-specific expression modulates metabolic reprogramming in diabetic cardiomyopathy: The role of SREBP1c lactylation in CD36-mediated lipotoxicity... <h4>Objective</h4>Diabetic cardiomyopathy (DCM) is characterized by metabolic dysfunction and lipotoxicity. The roles of acyl-CoA thioesterase 1 (ACOT1) and the novel post-translational modification lactylation in its pathogenesis remain unclear. This study aimed to investigate the stage-specific function of ACOT1 and the mechanism by which lactylation of SREBP1c regulates lipi
- PMID 42252558 (2026, Journal of cellular and molecular medicine) — Superoxide Dismutase-Centered Modulation by Curcumin in Cardiovascular Diseases: Mechanistic Insights and Translational Implications... Cardiovascular diseases (CVD) remain the leading global cause of morbidity and mortality, driven in part by dysregulated redox homeostasis and chronic inflammation. Superoxide dismutase (SOD), a key enzymatic defence against reactive oxygen species (ROS), plays a central role in maintaining cardiovascular integrity through regulation of oxidative stress across cytosolic (SOD1),
- PMID 41873711 (2026, Cardiovascular research) — METTL14 inhibits atherogenesis by epigenetically activating PPAR-α/γ transcription and fatty acid oxidation in VSMCs... <h4>Aims</h4>N6-methyladenosine (m6A) RNA modification can govern cell fate by co- or post-transcriptionally regulating gene expression. VSMCs can undergo phenotypic switching, contributing to other cells within atherosclerotic plaques, including foam cell- and macrophage-like cells. However, the role of VSMC m6A in atherosclerosis development remains unclear. While PPAR-α and
- PMID 42278379 (2026, International journal of molecular sciences) — The Pivotal Role of Plant Derivatives and Eicosanoid Signaling Modulation in Counteracting Cardiomiopathy... Eicosanoids and their receptors act as key regulators of inflammation, calcium homeostasis, mitochondrial function, and cardiomyocyte survival, thereby contributing to the onset and progression of cardiac dysfunction. This review aims to summarize the evidence to underscore the pivotal role of eicosanoids and their receptors in the pathophysiology of cardiomyopathy, analysing t
Source text: pdf-raw/evidence/europepmc_evidence_feline_hcm_diet_20260727.txt (Europe PMC first-hand abstracts, pulled 2026-07-27).