Evidence: protein-restricted diet in canine hepatic encephalopathy
Source: Europe PMC (Europe PubMed Central) REST search — first-hand peer-reviewed abstract records, pulled 2026-07-27. Query: hepatic encephalopathy dog diet. The cluster returns 880 records in Europe PMC; 6 representative studies are extracted below. Abstract text is verbatim from source; each study is traceable by PMID.
Studies
- PMID 42228606 (2026, Gut microbes) — Microbial shifts in early life: the pediatric gut microbiome and its role in health and disease... This review explores the pivotal role of the pediatric gut microbiome in shaping early-life development and influencing susceptibility to disease, emphasizing its impact on immune, metabolic, and neurodevelopmental processes. The neonatal period represents a critical window for host-microbiome interactions, beginning at birth when intestinal barrier function is still developing
- PMID 42278417 (2026, International journal of molecular sciences) — Potential Antidote Against Lead Toxicity-A Review... As chronic lead (Pb) exposure is a serious threat to public health in many countries, we intended to provide a review of the effective antidote for Pb intoxication. In this context, we explored the recent literature focusing on animal studies that provide clear evidence of the efficacy of supplementation with certain antioxidants, such as spirulina, curcumin, garlic, vitamin C,
- PMID 41922215 (2026, The Journal of veterinary medical science) — A canine case of multiple intrahepatic portosystemic shunts... An elderly, spayed female Maltese dog (10 years 3 months, 2.2 kg) presented with hyporexia, weight loss, polydipsia, and a staggering gait. Serum biochemistry analysis revealed increased aspartate aminotransferase, alanine transaminase, ammonia (226 μg/dL), and fasting total bile acids (130 μmol/L). Contrast-enhanced CT showed multiple clusters of contrast enhancement within th
- PMID 41920539 (2026, Veterinary medicine and science) — Occlusion of an Intrahepatic Portosystemic Shunt With an Amplatzer Septal Occluder Device in a Dog... This paper describes the use of an Amplatzer occluder device to attenuate an intrahepatic portosystemic shunt in a dog. To the authors' knowledge, this is the first description of the use of an Amplatzer occluder device for a large intrahepatic shunt. Shunt attenuation in this case was successful with no major complications. The use of such device could be made routine for bigg
- PMID 41976093 (2026, Animals : an open access journal from MDPI) — Evidence-Based Clinical Management of Canine Cognitive Dysfunction Syndrome: Diagnostic Algorithms, Practical Guidelines, Critical Appraisal of Biomarkers and Translational Limitations... Canine Cognitive Dysfunction Syndrome (CCDS) is a progressive neurodegenerative disease affecting older dogs that shares many pathological mechanisms with human Alzheimer's disease (AD). Although it is common in geriatric dogs, CCDS is often underdiagnosed in veterinary medicine. Both CCDS and AD involve a gradual decline in cognitive functions such as memory, learning and exec
- PMID 42076680 (2026, Veterinary sciences) — Postoperative Serum Quinolinic Acid and 3-Hydroxykynurenine in Dogs with Congenital Portosystemic Shunt: A Pilot Study of Their Association with Postattenuation Neurologic Signs... Postattenuation neurologic signs (PANS) are serious complications following surgical ligation of congenital portosystemic shunts (cPSS) in dogs, but their pathogenesis remains incompletely understood. We hypothesized that surgical ligation alters hepatic tryptophan metabolism through increased substrate delivery and inflammation, leading to changes in kynurenine pathway metabol
Source text: pdf-raw/evidence/europepmc_evidence_canine_hepatic_encephalopathy_diet_20260727.txt (Europe PMC first-hand abstracts, pulled 2026-07-27).