Evidence: dietary management of canine exocrine pancreatic insufficiency
Source: Europe PMC (Europe PubMed Central) REST search — first-hand peer-reviewed abstract records, pulled 2026-07-27. Query: exocrine pancreatic insufficiency dog diet. The cluster returns 5 records in Europe PMC; 6 representative studies are extracted below. Abstract text is verbatim from source; each study is traceable by PMID.
Studies
- PMID 41860870 (2026, The Journal of frailty & aging) — OLD DOG - Validating the dog as an animal model for human aging studies... Companion dogs represent a valuable and emerging translational model for human aging, as they share the human environment, receive comparable medical care - yet have much shorter lifespans. Despite their potential, a validated set of canine biomarkers of aging has not yet been established. The OLD-DOG Project, launched in 2023 at the University of Padua's Veterinary Teaching Ho *[CC BY — Open Access, verbatim with attribution.]*
- PMID 42188886 (2026, Veterinary sciences) — Effects of a Novel Prebiotic and Postbiotic Dietary Supplement on Gut Microbiota, Intestinal Barrier Markers, and Inflammation in Healthy Dogs... Although prebiotics and postbiotics support gastrointestinal health, evidence for their combined effects in dogs remains limited. This study evaluated a novel prebiotic and postbiotic supplement in healthy dogs undergoing a dietary transition. Thirty-six healthy adult dogs were randomly assigned to control group (CON, high-protein basal diet with placebo chew) or treatment grou *[CC BY — Open Access, verbatim with attribution.]*
- PMID 41897963 (2026, Animals : an open access journal from MDPI) — Intestinal Dysbiosis Relating to Gut-Brain Axis and Behavior in Dogs: A Systematic Review with Text Mining Approach... The intestinal microbiome plays a fundamental role in canine health and well-being, regulating functions, including digestion, immunity, metabolism, and behavior. Dysbiosis refers to the disruption of the balanced composition of resident commensal communities, and gut bacteria can influence behavior via neurological, metabolic, endocrine, and immune-mediated pathways. Growing e *[CC BY — Open Access, verbatim with attribution.]*
- PMID 41863224 (2026, Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc) — *[Paraphrased derived summary — non-Open-Access source.]* A case report describes emphysematous gastritis—a rare, serious gas-producing infection—in a 7-year-old dog with 12-day ileus, chronic pancreatitis, and exocrine pancreatic insufficiency; gastric histopathology (excerpt cut off) supported the diagnosis.
- PMID 41745976 (2026, Veterinary sciences) — The Collaborative Collapse: Bile Acid Dysmetabolism as a Central Pathogenic Driver in Canine and Feline Multi-Systemic Disorders-From Mechanisms to Precision Therapeutics... Veterinary metabolomics has redefined bile acids (BAs) from simple digestive surfactants to systemic endocrine signals within a microbial-host metabolic axis. This review aims to evaluate how BA dysmetabolism acts as a central pathogenic factor in canine and feline disease. We analyze the BA pool's integrity, which depends on a specialized functional guild, primarily <i>Peptace *[CC BY — Open Access, verbatim with attribution.]*
Source text: pdf-raw/evidence/europepmc_evidence_canine_epi_diet_20260727.txt (Europe PMC first-hand abstracts, pulled 2026-07-27).
License & attribution
Mixed licensing per COPYRIGHT_POLICY §3: Open Access (CC BY / CC BY-NC / CC BY-NC-ND) studies are reproduced verbatim with attribution under their specific CC license; non-Open-Access studies are paraphrased as derived fact summaries (numbers and proper nouns preserved, sentences rewritten). Original records:
- https://pubmed.ncbi.nlm.nih.gov/41860870/
- https://pubmed.ncbi.nlm.nih.gov/42188886/
- https://pubmed.ncbi.nlm.nih.gov/41897963/
- https://pubmed.ncbi.nlm.nih.gov/41863224/
- https://pubmed.ncbi.nlm.nih.gov/41745976/
Cleaning removal log (2026-08-05, codebuddy)
PMID 41891386 — Human meta-analysis of chronic pancreatitis research (PubMed/MeSH, no canine content).