Cat (Felis catus) — XY difference of sexual development, generic (hereditary; OMIA-verified species predisposition)

--- license: permission_granted topic_id: companion_species_health_xy_difference_of_sexual_development_generic_cat category: companion-species-health title: "Cat (Felis catus) — XY difference of sexual development, generic (hereditary; OMIA-verified species predisposition)" lang: en source: "OMIA (Online Mendelian Inheritance in Animals, University of Sydney) species-specific hereditary-disorder record, saved verbatim to source_file; C1 substring-verified. Pulled 2026-08-24 from local OMIA database dump." source_file: pdf-raw/species-health/cat_xy_difference_of_sexual_development_generic_5052.txt date_parsed: 2026-08-24 tokens_estimated: 145 verification: method: substring_match claims: 3 passed: 3 date: 2026-08-24 recovered: false path: companion-species-health/companion_species_health_xy_difference_of_sexual_development_generic_cat/01_companion_species_health_xy_difference_of_sexual_development_generic_cat.md source_document: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" citation: authority: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" title: "Cat (Felis catus) — XY difference of sexual development, generic (hereditary; OMIA-verified species predisposition)" url: "https://omia.org/OMIA001601/9685/" retrieved: "2026-08-24" ref: "OMIA species-specific hereditary-disorder records (omia.org), derived from local OMIA database dump; dataset: https://doi.org/10.25910/2AMR-PV70" doc_type: "academic animal-genetics database (species-specific disorder entries)" needs_review: false

verification_derived: method: derived_from_dataset source: "OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM" note: "Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose." verification_derived: method: derived_from_dataset source: "OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM" note: "Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose."---

Cat (Felis catus) — XY difference of sexual development, generic (hereditary; OMIA-verified species predisposition)

Source: first-hand OMIA (University of Sydney) species-specific hereditary-disorder record, saved verbatim to source_file; every claim below is a C1 byte-substring of it.

Claims

• Species: Cat (Felis catus)
• Disorder: XY difference of sexual development, generic
• Summary: Stachowiak et al. (2022) "performed comprehensive cytogenetic, molecular, and histological studies of 17 cats with abnormal external genitalia, unusual behavior, or tricolor coats (atypical in males). The DSD phenotype of three cats was associated with sex chromosome abnormalities: X/Y translocation (38,XXSRY+), 37,X/38,XY mosaicism, and XX/XY leukocyte chimerism. The remaining 14 affected cats were classified as XY DSD (SRY-positive)."

Evidence (references)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

• 1997. Male pseudohermaphroditism in a cat. J Small Anim Pract — PubMed:PMID9121130 | DOI:10.1111/j.1748-5827.1997.tb02981.x — OMIA Phene_Article / Article
• 2011. A case of SRY-positive 38,XY true hermaphroditism (XY sex reversal) in a cat. Vet Pathol — PubMed:PMID20861501 | DOI:10.1177/0300985810382093 — OMIA Phene_Article / Article
• 2020. Genetic disorders of sex development in cats: An update. Anim Reprod Sci — PubMed:PMID32414464 | DOI:10.1016/j.anireprosci.2020.106353 — OMIA Phene_Article / Article
• 2015. Ein Fall von SRY positiver Sex-Umkehr bei einer Hauskatze [A case of SRY positive sex reversal in a domestic cat]. Schweiz Arch Tierheilkd — PubMed:PMID26753328 | DOI:10.17236/sat00013 — OMIA Phene_Article / Article
• 2014. Testicular disorder of sex development in four cats with a male karyotype (38,XY; SRY-positive). Anim Reprod Sci — PubMed:PMID25455261 | DOI:10.1016/j.anireprosci.2014.10.001 — OMIA Phene_Article / Article
• 2022. Cytogenetic and molecular insight into the genetic background of disorders of sex development in seventeen cats. Sci Rep — PubMed:PMID36280698 | DOI:10.1038/s41598-022-21718-y — OMIA Phene_Article / Article

Evidence (references)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

• 1997. Male pseudohermaphroditism in a cat. J Small Anim Pract — PubMed:PMID9121130 | DOI:10.1111/j.1748-5827.1997.tb02981.x — OMIA Phene_Article / Article
• 2011. A case of SRY-positive 38,XY true hermaphroditism (XY sex reversal) in a cat. Vet Pathol — PubMed:PMID20861501 | DOI:10.1177/0300985810382093 — OMIA Phene_Article / Article
• 2020. Genetic disorders of sex development in cats: An update. Anim Reprod Sci — PubMed:PMID32414464 | DOI:10.1016/j.anireprosci.2020.106353 — OMIA Phene_Article / Article
• 2015. Ein Fall von SRY positiver Sex-Umkehr bei einer Hauskatze [A case of SRY positive sex reversal in a domestic cat]. Schweiz Arch Tierheilkd — PubMed:PMID26753328 | DOI:10.17236/sat00013 — OMIA Phene_Article / Article
• 2014. Testicular disorder of sex development in four cats with a male karyotype (38,XY; SRY-positive). Anim Reprod Sci — PubMed:PMID25455261 | DOI:10.1016/j.anireprosci.2014.10.001 — OMIA Phene_Article / Article
• 2022. Cytogenetic and molecular insight into the genetic background of disorders of sex development in seventeen cats. Sci Rep — PubMed:PMID36280698 | DOI:10.1038/s41598-022-21718-y — OMIA Phene_Article / Article