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Horse (Equus caballus) — Male subfertility (hereditary; OMIA-verified species predisposition)

companion_species_health_male_subfertility_horse

--- license: permission_granted topic_id: companion_species_health_male_subfertility_horse category: companion-species-health title: "Horse (Equus caballus) — Male subfertility (hereditary; OMIA-verified species predisposition)" lang: en source: "OMIA (Online Mendelian Inheritance in Animals, University of Sydney) species-specific hereditary-disorder record, saved verbatim to source_file; C1 substring-verified. Pulled 2026-08-24 from local OMIA database dump." source_file: pdf-raw/species-health/horse_male_subfertility_5075.txt date_parsed: 2026-08-24 tokens_estimated: 80 verification: method: substring_match claims: 3 passed: 3 date: 2026-08-24 recovered: false path: companion-species-health/companion_species_health_male_subfertility_horse/01_companion_species_health_male_subfertility_horse.md source_document: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" citation: authority: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" title: "Horse (Equus caballus) — Male subfertility (hereditary; OMIA-verified species predisposition)" url: "https://omia.org/OMIA002354/9796/" retrieved: "2026-08-24" ref: "OMIA species-specific hereditary-disorder records (omia.org), derived from local OMIA database dump; dataset: https://doi.org/10.25910/2AMR-PV70" doc_type: "academic animal-genetics database (species-specific disorder entries)" needs_review: false

verification_derived: method: derived_from_dataset source: "OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM" note: "Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose." verification_derived: method: derived_from_dataset source: "OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM" note: "Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose."---

Horse (Equus caballus) — Male subfertility (hereditary; OMIA-verified species predisposition)

Source: first-hand OMIA (University of Sydney) species-specific hereditary-disorder record, saved verbatim to source_file; every claim below is a C1 byte-substring of it.

Claims

  • Species: Horse (Equus caballus)
  • Disorder: Male subfertility
  • Summary: See also OMIA:001762-9796 : Impaired acrosomal reaction in Equus caballus (horse)

Evidence (references)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

  • 2012. Genome-wide association study implicates testis-sperm specific FKBP6 as a susceptibility locus for impaired acrosome reaction in stallions. PLoS Genet — PubMed:PMID23284302 | DOI:10.1371/journal.pgen.1003139 — OMIA Phene_Article / Article
  • 2022. Copy number variation of horse Y chromosome genes in normal equine populations and in horses with abnormal sex development and subfertility: relationship of copy number variations with Y haplogroups. G3 (Bethesda) — PubMed:PMID36227030 | DOI:10.1093/g3journal/jkac278 — OMIA Phene_Article / Article
  • 2024. Proteomic analysis of sperm from fertile stallions and subfertile stallions due to impaired acrosomal exocytosis. Sci Rep — PubMed:PMID38816557 | DOI:10.1038/s41598-024-63410-3 — OMIA Phene_Article / Article
  • 2024. Spermatozoal acrosome dysfunction and its role in stallion subfertility. J Equine Vet Sci — PubMed:PMID39490453 | DOI:10.1016/j.jevs.2024.105213 — OMIA Phene_Article / Article

Evidence (references)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

  • 2012. Genome-wide association study implicates testis-sperm specific FKBP6 as a susceptibility locus for impaired acrosome reaction in stallions. PLoS Genet — PubMed:PMID23284302 | DOI:10.1371/journal.pgen.1003139 — OMIA Phene_Article / Article
  • 2022. Copy number variation of horse Y chromosome genes in normal equine populations and in horses with abnormal sex development and subfertility: relationship of copy number variations with Y haplogroups. G3 (Bethesda) — PubMed:PMID36227030 | DOI:10.1093/g3journal/jkac278 — OMIA Phene_Article / Article
  • 2024. Proteomic analysis of sperm from fertile stallions and subfertile stallions due to impaired acrosomal exocytosis. Sci Rep — PubMed:PMID38816557 | DOI:10.1038/s41598-024-63410-3 — OMIA Phene_Article / Article
  • 2024. Spermatozoal acrosome dysfunction and its role in stallion subfertility. J Equine Vet Sci — PubMed:PMID39490453 | DOI:10.1016/j.jevs.2024.105213 — OMIA Phene_Article / Article

Sources