--- license: permission_granted topic_id: companion_species_health_hypophosphatemic_rickets_autosomal_recessive_1_rabbit category: companion-species-health title: "Rabbit (Oryctolagus cuniculus) — Hypophosphatemic rickets, autosomal recessive, 1 (hereditary; OMIA-verified species predisposition)" lang: en source: "OMIA (Online Mendelian Inheritance in Animals, University of Sydney) species-specific hereditary-disorder record, saved verbatim to source_file; C1 substring-verified. Pulled 2026-08-24 from local OMIA database dump." source_file: pdf-raw/species-health/rabbit_hypophosphatemic_rickets_autosomal_recessive_1_4397.txt date_parsed: 2026-08-24 tokens_estimated: 102 verification: method: substring_match claims: 3 passed: 3 date: 2026-08-24 recovered: false path: companion-species-health/companion_species_health_hypophosphatemic_rickets_autosomal_recessive_1_rabbit/01_companion_species_health_hypophosphatemic_rickets_autosomal_recessive_1_rabbit.md source_document: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" citation: authority: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" title: "Rabbit (Oryctolagus cuniculus) — Hypophosphatemic rickets, autosomal recessive, 1 (hereditary; OMIA-verified species predisposition)" url: "https://omia.org/OMIA001542/9986/" retrieved: "2026-08-24" ref: "OMIA species-specific hereditary-disorder records (omia.org), derived from local OMIA database dump; dataset: https://doi.org/10.25910/2AMR-PV70" doc_type: "academic animal-genetics database (species-specific disorder entries)" needs_review: false
verification_derived: method: derived_from_dataset source: "OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM" note: "Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose."---
Rabbit (Oryctolagus cuniculus) — Hypophosphatemic rickets, autosomal recessive, 1 (hereditary; OMIA-verified species predisposition)
Source: first-hand OMIA (University of Sydney) species-specific hereditary-disorder record, saved verbatim to source_file; every claim below is a C1 byte-substring of it.
Claims
Species: Rabbit (Oryctolagus cuniculus)Disorder: Hypophosphatemic rickets, autosomal recessive, 1Summary: Liu et al. (2019) "deleted the DMP1 gene in rabbit using CRISPR/Cas9. This rabbit model recapitulated many features of human ARHR" [autosomal recessive form of hypophosphatemic rickets]. This model is, therefore, a genetically-modified organism (GMO).
Associated gene(s)
Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.
- Gene: Entrez Gene ID 389111537 (no symbol in OMIA GeneSynonym) — OMIA Phene_Gene
Evidence (references)
Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.
- 2019. DMP1 ablation in the rabbit results in mineralization defects and abnormalities in Haversian canal/osteon microarchitecture. J Bone Miner Res — PubMed:PMID30827034 | DOI:10.1002/jbmr.3683 — OMIA Phene_Article / Article
Comparative medicine (human OMIM)
Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.
- OMIM:241520 (type: trait) — OMIA Group_OMIM (via OMIA_ID)
- OMIM:600980 (type: gene) — OMIA Group_OMIM (via OMIA_ID)