--- license: permission_granted topic_id: companion_species_health_hypertriglyceridemia_hamster category: companion-species-health title: "Hamster — Hypertriglyceridemia (hereditary; OMIA-verified species predisposition)" lang: en source: "OMIA (Online Mendelian Inheritance in Animals, University of Sydney) species-specific hereditary-disorder record, saved verbatim to source_file; C1 substring-verified. Pulled 2026-08-24 from local OMIA database dump." source_file: pdf-raw/species-health/hamster_hypertriglyceridemia_6235.txt date_parsed: 2026-08-24 tokens_estimated: 127 verification: method: substring_match claims: 4 passed: 4 date: 2026-08-24 recovered: false path: companion-species-health/companion_species_health_hypertriglyceridemia_hamster/01_companion_species_health_hypertriglyceridemia_hamster.md source_document: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" citation: authority: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" title: "Hamster — Hypertriglyceridemia (hereditary; OMIA-verified species predisposition)" url: "https://omia.org/OMIA002915/10036/" retrieved: "2026-08-24" ref: "OMIA species-specific hereditary-disorder records (omia.org), derived from local OMIA database dump; dataset: https://doi.org/10.25910/2AMR-PV70" doc_type: "academic animal-genetics database (species-specific disorder entries)" needs_review: false
verification_derived: method: derived_from_dataset source: "OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM" note: "Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose."---
Hamster — Hypertriglyceridemia (hereditary; OMIA-verified species predisposition)
Source: first-hand OMIA (University of Sydney) species-specific hereditary-disorder record, saved verbatim to source_file; every claim below is a C1 byte-substring of it.
Claims
Species: Mesocricetus auratus / Phodopus spp. (hamster)Disorder: HypertriglyceridemiaSummary: Shen et al. (2024): Acute seizure models were established both in vivo and ex vivo using wild-type and Apolipoprotein C2 knockout ( Apoc2 −/− ) hamsters. ... Hypertriglyceridemic Apoc2 −/− hamsters exhibited reduced seizure frequency and decreased cortical neuron excitability." This study involves gene edited or genetically modified organisms (GMO).Defect: yes
Associated gene(s)
Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.
- Gene: Entrez Gene ID 398298976 (no symbol in OMIA GeneSynonym) — OMIA Phene_Gene
Evidence (references)
Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.
- 2020. ApoC2 deficiency elicits severe hypertriglyceridemia and spontaneous atherosclerosis: A rodent model rescued from neonatal death. Metabolism — PubMed:PMID32562799 | DOI:10.1016/j.metabol.2020.154296 — OMIA Phene_Article / Article
- 2024. Decreased neuronal excitability in hypertriglyceridemia hamsters with acute seizures. Front Neurol — PubMed:PMID39811454 | DOI:10.3389/fneur.2024.1500737 — OMIA Phene_Article / Article
Comparative medicine (human OMIM)
Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.
- OMIM:608083 (type: gene) — OMIA Group_OMIM (via OMIA_ID)
- OMIM:207750 (type: None) — OMIA Group_OMIM (via OMIA_ID)