--- license: permission_granted topic_id: companion_species_health_hyperlipidaemia_atherosclerosis_apoe_related_rabbit category: companion-species-health title: "Rabbit (Oryctolagus cuniculus) — Hyperlipidaemia/atherosclerosis, APOE-related (hereditary; OMIA-verified species predisposition)" lang: en source: "OMIA (Online Mendelian Inheritance in Animals, University of Sydney) species-specific hereditary-disorder record, saved verbatim to source_file; C1 substring-verified. Pulled 2026-08-24 from local OMIA database dump." source_file: pdf-raw/species-health/rabbit_hyperlipidaemia_atherosclerosis_apoe_related_3953.txt date_parsed: 2026-08-24 tokens_estimated: 80 verification: method: substring_match claims: 3 passed: 3 date: 2026-08-24 recovered: false path: companion-species-health/companion_species_health_hyperlipidaemia_atherosclerosis_apoe_related_rabbit/01_companion_species_health_hyperlipidaemia_atherosclerosis_apoe_related_rabbit.md source_document: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" citation: authority: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" title: "Rabbit (Oryctolagus cuniculus) — Hyperlipidaemia/atherosclerosis, APOE-related (hereditary; OMIA-verified species predisposition)" url: "https://omia.org/OMIA002063/9986/" retrieved: "2026-08-24" ref: "OMIA species-specific hereditary-disorder records (omia.org), derived from local OMIA database dump; dataset: https://doi.org/10.25910/2AMR-PV70" doc_type: "academic animal-genetics database (species-specific disorder entries)" needs_review: false
verification_derived: method: derived_from_dataset source: "OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM" note: "Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose."---
Rabbit (Oryctolagus cuniculus) — Hyperlipidaemia/atherosclerosis, APOE-related (hereditary; OMIA-verified species predisposition)
Source: first-hand OMIA (University of Sydney) species-specific hereditary-disorder record, saved verbatim to source_file; every claim below is a C1 byte-substring of it.
Claims
Species: Rabbit (Oryctolagus cuniculus)Disorder: Hyperlipidaemia/atherosclerosis, APOE-relatedSummary: This is a genetically-modified organism (GMO)
Associated gene(s)
Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.
- Gene: Entrez Gene ID 388912575 (no symbol in OMIA GeneSynonym) — OMIA Phene_Gene
Evidence (references)
Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.
- 2016. ApoE knockout rabbits: A novel model for the study of human hyperlipidemia. Atherosclerosis — PubMed:PMID26724529 | DOI:10.1016/j.atherosclerosis.2015.12.002 — OMIA Phene_Article / Article
- 2020. Animal models of human atherosclerosis: current progress. Braz J Med Biol Res — PubMed:PMID32428130 | DOI:10.1590/1414-431x20209557 — OMIA Phene_Article / Article
- 2020. Apolipoprotein E knockout rabbit model of intracranial atherosclerotic disease. Animal Model Exp Med — PubMed:PMID32613180 | DOI:10.1002/ame2.12125 — OMIA Phene_Article / Article
- 2021. Research methods for animal models of atherosclerosis (Review). Mol Med Rep — PubMed:PMID34713295 | DOI:10.3892/mmr.2021.12511 — OMIA Phene_Article / Article
- 2024. Enhanced atherosclerosis in apolipoprotein E knockout rabbits: role of apoB48-rich remnant lipoproteins. Front Cardiovasc Med — PubMed:PMID39087075 | DOI:10.3389/fcvm.2024.1424064 — OMIA Phene_Article / Article
Comparative medicine (human OMIM)
Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.
- OMIM:107741 (type: gene) — OMIA Group_OMIM (via OMIA_ID)
- OMIM:617347 (type: trait) — OMIA Group_OMIM (via OMIA_ID)