Dog (Canis lupus familiaris) — Fanconi syndrome (hereditary; OMIA-verified species predisposition)

--- license: permission_granted topic_id: companion_species_health_fanconi_syndrome_dog category: companion-species-health title: "Dog (Canis lupus familiaris) — Fanconi syndrome (hereditary; OMIA-verified species predisposition)" lang: en source: "OMIA (Online Mendelian Inheritance in Animals, University of Sydney) species-specific hereditary-disorder record, saved verbatim to source_file; C1 substring-verified. Pulled 2026-08-24 from local OMIA database dump." source_file: pdf-raw/species-health/dog_fanconi_syndrome_655.txt date_parsed: 2026-08-24 tokens_estimated: 215 verification: method: substring_match claims: 3 passed: 3 date: 2026-08-24 recovered: false path: companion-species-health/companion_species_health_fanconi_syndrome_dog/01_companion_species_health_fanconi_syndrome_dog.md source_document: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" citation: authority: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" title: "Dog (Canis lupus familiaris) — Fanconi syndrome (hereditary; OMIA-verified species predisposition)" url: "https://omia.org/OMIA000366/9615/" retrieved: "2026-08-24" ref: "OMIA species-specific hereditary-disorder records (omia.org), derived from local OMIA database dump; dataset: https://doi.org/10.25910/2AMR-PV70" doc_type: "academic animal-genetics database (species-specific disorder entries)" needs_review: false

verification_derived: method: derived_from_dataset source: "OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM" note: "Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose."---

Dog (Canis lupus familiaris) — Fanconi syndrome (hereditary; OMIA-verified species predisposition)

Source: first-hand OMIA (University of Sydney) species-specific hereditary-disorder record, saved verbatim to source_file; every claim below is a C1 byte-substring of it.

Claims

• Species: Dog (Canis lupus familiaris)
• Disorder: Fanconi syndrome
• Summary: Fanconi syndrome is a proximal renal tubular defect affecting the resorption of various substances filtered by the glomeruli. In addition to genetic forms, acquired proximal renal tubulopathies are also called Fanconi syndrome and have been reported in dogs to be related to excessive ingestion of jerky treats, gentamicin therapy, primary hypoparathyroidism, ethylene glycol toxicity, presumed pyelonephritis and copper storage hepatopathy. This entry lists references to (suspected) genetic and acquired forms of the disease. Information relating to inherited Fanconi Syndrome in Basenji dogs due to a mutation in the FAN1 gene have been moved to ' OMIA:002683-9615 : Fanconi syndrome, FAN1-related in Canis lupus familiaris' [2/5/2023]

Evidence (references)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

• 1970. Familial renal disease in Norwegian Elkhound dogs. J Am Vet Med Assoc — PubMed:PMID5462987 — OMIA Phene_Article / Article
• 1993. Canine Fanconi syndrome. Journal of Small Animal Practice — OMIA Phene_Article / Article
• 1994. Fanconi syndrome in a Labrador Retriever. Journal of Veterinary Internal Medicine — PubMed:PMID7884724 — OMIA Phene_Article / Article
• 1995. Fanconi Syndrome associated with amoxicillin therapy in the dog. Canine Practice — OMIA Phene_Article / Article
• 1996. Congenital Fanconi syndrome associated with renal dysplasia in 2 Border Terriers. Journal of Veterinary Internal Medicine — PubMed:PMID8947876 — OMIA Phene_Article / Article
• 2004. Survival time, lifespan, and quality of life in dogs with idiopathic Fanconi syndrome. J Am Vet Med Assoc — PubMed:PMID15328712 | DOI:10.2460/javma.2004.225.377 — OMIA Phene_Article / Article
• 2004. Transient proximal renal tubular acidosis and Fanconi syndrome in a dog. J Am Vet Med Assoc — PubMed:PMID15154730 — OMIA Phene_Article / Article
• 1979. Characterization of renal defects in dogs with a syndrome similar to the Fanconi syndrome in man. J Am Vet Med Assoc — PubMed:PMID438041 — OMIA Phene_Article / Article
• 1978. Spontaneous Fanconi syndrome in the dog. Metabolism — PubMed:PMID619225 | DOI:10.1016/0026-0495(78)90122-1 — OMIA Phene_Article / Article
• 2011. Fanconi syndrome in four non-basenji dogs exposed to chicken jerky treats. J Am Anim Hosp Assoc — PubMed:PMID22058368 | DOI:10.5326/JAAHA-MS-5602 — OMIA Phene_Article / Article
• 2008. Concurrent hepatic copper toxicosis and Fanconi's syndrome in a dog. J Vet Intern Med — PubMed:PMID18289313 | DOI:10.1111/j.1939-1676.2007.0040.x — OMIA Phene_Article / Article
• 2014. Transient Fanconi syndrome with severe polyuria and polydipsia in a 4-year old Shih Tzu fed chicken jerky treats. Schweiz Arch Tierheilkd — PubMed:PMID25497565 | DOI:10.1024/0036-7281/a000655 — OMIA Phene_Article / Article
• (6 additional references in OMIA)

Comparative medicine (human OMIM)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

• OMIM:227810 (type: trait) — OMIA Group_OMIM (via OMIA_ID)
• OMIM:138160 (type: gene) — OMIA Group_OMIM (via OMIA_ID)