← All Topics / companion-species-health

Cat (Felis catus) — Cryptorchidism (hereditary; OMIA-verified species predisposition)

companion_species_health_cryptorchidism_cat

companion-species-health en

--- license: permission_granted topic_id: companion_species_health_cryptorchidism_cat category: companion-species-health title: "Cat (Felis catus) — Cryptorchidism (hereditary; OMIA-verified species predisposition)" lang: en source: "OMIA (Online Mendelian Inheritance in Animals, University of Sydney) species-specific hereditary-disorder record, saved verbatim to source_file; C1 substring-verified. Pulled 2026-08-24 from local OMIA database dump." source_file: pdf-raw/species-health/cat_cryptorchidism_473.txt date_parsed: 2026-08-24 tokens_estimated: 420 verification: method: substring_match claims: 8 passed: 8 date: 2026-08-24 recovered: false path: companion-species-health/companion_species_health_cryptorchidism_cat/01_companion_species_health_cryptorchidism_cat.md source_document: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" citation: authority: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" title: "Cat (Felis catus) — Cryptorchidism (hereditary; OMIA-verified species predisposition)" url: "https://omia.org/OMIA000243/9685/" retrieved: "2026-08-24" ref: "OMIA species-specific hereditary-disorder records (omia.org), derived from local OMIA database dump; dataset: https://doi.org/10.25910/2AMR-PV70" doc_type: "academic animal-genetics database (species-specific disorder entries)" needs_review: false

verification_derived: method: derived_from_dataset source: "OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM" note: "Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose." verification_derived: method: derived_from_dataset source: "OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM" note: "Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose."---

Cat (Felis catus) — Cryptorchidism (hereditary; OMIA-verified species predisposition)

Source: first-hand OMIA (University of Sydney) species-specific hereditary-disorder record, saved verbatim to source_file; every claim below is a C1 byte-substring of it.

Claims

  • Species: Cat (Felis catus)
  • Disorder: Cryptorchidism
  • Summary: Cryptorchidism is characterized by the presence of one or two undescended testes in an otherwise phenotypically normal male (isolated cryptorchidism). It is uncommon in this species. Breeding of affected cats is discouraged.
  • Clin feat: Affected cats have either one or two undescended testes. Since verification of scrotal testes by palpation is challenging in young kittens, affected cats are often diagnosed when presented for neutering. The undescended testis may be located anywhere from the caudal pole of the kidney to the inguinal canal, or outside of the canal but cranial to the scrotum (Meyers-Wallen, 2011).
  • Pathology: Unilateral cryptorchid cats may have reduced fertility and bilateral cryptorchid cats are sterile, as spermatogonia are depleted in undescended testes. Cryptorchid testes can occur in association with other types of XY DSD, such as XY sex reversal (Schlafer et al., 2011; OMIA#000791-9685) and Persistent Müllerian Duct Syndrome (Schulman and Levine 1989; OMIA#000791-9685)).
  • Prevalence: Feline isolated cryptorchidism is uncommon, ranging from only 1.3% to 1.7% of cats presented for neutering. Most affected cats are unilaterally cryptorchid, and Persians may have a higher prevalence than other breeds (Yates et al., 2003; Millis et al., 1992).
  • Control: Breeding of fertile cryptorchid animals (as well as their parents or siblings) is discouraged. The AVMA states that it is unethical for a veterinarian to surgically correct cryptorchidism without also sterilizing the animal.
  • Gen test: There are no genetic tests available at this time.

Evidence (references)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

  • 1992. Cryptorchidism and Monorchism in Cats - 25 Cases (1980-1989). Journal of the American Veterinary Medical Association — PubMed:PMID1351479 — OMIA Phene_Article / Article
  • 1993. Cryptorchidism in Cats. Compendium on Continuing Education for the Practicing Veterinarian — OMIA Phene_Article / Article
  • 2001. Cryptorchidism in cats. Veterinary Record — PubMed:PMID11558670 — OMIA Phene_Article / Article
  • 2001. Cryptorchidism and alopecia in cats. Veterinary Record — PubMed:PMID11570800 — OMIA Phene_Article / Article
  • 2003. Incidence of cryptorchidism in dogs and cats. Veterinary Record — PubMed:PMID12733559 — OMIA Phene_Article / Article
  • 1989. Pyometra involving uterus masculinus in a cat. J Am Vet Med Assoc — PubMed:PMID2925486 — OMIA Phene_Article / Article
  • 2011. A case of SRY-positive 38,XY true hermaphroditism (XY sex reversal) in a cat. Vet Pathol — PubMed:PMID20861501 | DOI:10.1177/0300985810382093 — OMIA Phene_Article / Article
  • 2008. Cryptorchidism. Compend Contin Educ Vet — PubMed:PMID18690608 — OMIA Phene_Article / Article
  • 2010. Analysis of single nucleotide polymorphisms in the 3' region of the estrogen receptor 1 gene in normal and cryptorchid Miniature Dachshunds and Chihuahuas. J Reprod Dev — PubMed:PMID20453437 — OMIA Phene_Article / Article
  • 2000. Insulin-like 3/relaxin-like factor gene mutations are associated with cryptorchidism. J Clin Endocrinol Metab — PubMed:PMID11095425 — OMIA Phene_Article / Article
  • 2003. The INSL3-LGR8/GREAT ligand-receptor pair in human cryptorchidism. J Clin Endocrinol Metab — PubMed:PMID12970298 — OMIA Phene_Article / Article
  • 2012. Gonadal and sex differentiation abnormalities of dogs and cats. Sex Dev — PubMed:PMID22005097 | DOI:10.1159/000332740 — OMIA Phene_Article / Article
  • (6 additional references in OMIA)

Comparative medicine (human OMIM)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

  • OMIM:219050 (type: trait) — OMIA Group_OMIM (via OMIA_ID)

Evidence (references)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

  • 1992. Cryptorchidism and Monorchism in Cats - 25 Cases (1980-1989). Journal of the American Veterinary Medical Association — PubMed:PMID1351479 — OMIA Phene_Article / Article
  • 1993. Cryptorchidism in Cats. Compendium on Continuing Education for the Practicing Veterinarian — OMIA Phene_Article / Article
  • 2001. Cryptorchidism in cats. Veterinary Record — PubMed:PMID11558670 — OMIA Phene_Article / Article
  • 2001. Cryptorchidism and alopecia in cats. Veterinary Record — PubMed:PMID11570800 — OMIA Phene_Article / Article
  • 2003. Incidence of cryptorchidism in dogs and cats. Veterinary Record — PubMed:PMID12733559 — OMIA Phene_Article / Article
  • 1989. Pyometra involving uterus masculinus in a cat. J Am Vet Med Assoc — PubMed:PMID2925486 — OMIA Phene_Article / Article
  • 2011. A case of SRY-positive 38,XY true hermaphroditism (XY sex reversal) in a cat. Vet Pathol — PubMed:PMID20861501 | DOI:10.1177/0300985810382093 — OMIA Phene_Article / Article
  • 2008. Cryptorchidism. Compend Contin Educ Vet — PubMed:PMID18690608 — OMIA Phene_Article / Article
  • 2010. Analysis of single nucleotide polymorphisms in the 3' region of the estrogen receptor 1 gene in normal and cryptorchid Miniature Dachshunds and Chihuahuas. J Reprod Dev — PubMed:PMID20453437 — OMIA Phene_Article / Article
  • 2000. Insulin-like 3/relaxin-like factor gene mutations are associated with cryptorchidism. J Clin Endocrinol Metab — PubMed:PMID11095425 — OMIA Phene_Article / Article
  • 2003. The INSL3-LGR8/GREAT ligand-receptor pair in human cryptorchidism. J Clin Endocrinol Metab — PubMed:PMID12970298 — OMIA Phene_Article / Article
  • 2012. Gonadal and sex differentiation abnormalities of dogs and cats. Sex Dev — PubMed:PMID22005097 | DOI:10.1159/000332740 — OMIA Phene_Article / Article
  • (6 additional references in OMIA)

Comparative medicine (human OMIM)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

  • OMIM:219050 (type: trait) — OMIA Group_OMIM (via OMIA_ID)

Sources

Cat (Felis catus) — Cryptorchidism (hereditary; OMIA-verified species predisposition)
companion-species-healthPMID 1351479

Machine access

AI agents: this page mirrors GET /api/v1/llm_context?topic=companion_species_health_cryptorchidism_cat (max 500 tokens, whitelisted). Rate limit 60 req/min for recognized AI crawlers.

Raw JSON ↗ llm.txt OpenAPI