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Dog (Canis lupus familiaris) — BOAS (hereditary; OMIA-verified species predisposition)

companion_species_health_boas_dog

companion-species-health en

--- license: permission_granted topic_id: companion_species_health_boas_dog category: companion-species-health title: "Dog (Canis lupus familiaris) — BOAS (hereditary; OMIA-verified species predisposition)" lang: en source: "OMIA (Online Mendelian Inheritance in Animals, University of Sydney) species-specific hereditary-disorder record, saved verbatim to source_file; C1 substring-verified. Pulled 2026-08-24 from local OMIA database dump." source_file: pdf-raw/species-health/dog_boas_305.txt date_parsed: 2026-08-24 tokens_estimated: 164 verification: method: substring_match claims: 3 passed: 3 date: 2026-08-24 recovered: false path: companion-species-health/companion_species_health_boas_dog/01_companion_species_health_boas_dog.md source_document: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" citation: authority: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" title: "Dog (Canis lupus familiaris) — BOAS (hereditary; OMIA-verified species predisposition)" url: "https://omia.org/OMIA000145/9615/" retrieved: "2026-08-24" ref: "OMIA species-specific hereditary-disorder records (omia.org), derived from local OMIA database dump; dataset: https://doi.org/10.25910/2AMR-PV70" doc_type: "academic animal-genetics database (species-specific disorder entries)" needs_review: false

verification_derived: method: derived_from_dataset source: "OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM" note: "Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose." verification_derived: method: derived_from_dataset source: "OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM" note: "Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose."---

Dog (Canis lupus familiaris) — BOAS (hereditary; OMIA-verified species predisposition)

Source: first-hand OMIA (University of Sydney) species-specific hereditary-disorder record, saved verbatim to source_file; every claim below is a C1 byte-substring of it.

Claims

  • Species: Dog (Canis lupus familiaris)
  • Disorder: BOAS
  • Summary: Brachycephalic Obstructive Airway Syndrome (BOAS) is a condition where the animal's ability to breathe, as well as it's ability to engage in normal behaviours is impacted negatively due to brachycephaly (the shape of a skull is shorter than typical for its species). In dogs, narrowed nostrils (stenotic nares), elongated soft palate, enlarged tongue, and reduced diameter of the windpipe have been associated with the condition (Ekenstedt et al., 2023). Elongated soft palates have been reported in non-brachycephalic dogs (Himel et al., 2023).

Evidence (references)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

  • 1989. Inherited and congenital airway conditions in dogs and cats. Journal of Small Animal Practice — OMIA Phene_Article / Article
  • 1997. Brachycephalic airway obstruction syndrome - a review of 118 cases. Canine Practice — OMIA Phene_Article / Article
  • 2010. Brachycephalic airway obstructive syndrome in dogs: 90 cases (1991-2008). J Am Vet Med Assoc — PubMed:PMID21034343 | DOI:10.2460/javma.237.9.1048 — OMIA Phene_Article / Article
  • 1992. Brachycephalic airway syndrome. Vet Clin North Am Small Anim Pract — PubMed:PMID1523786 — OMIA Phene_Article / Article
  • 1991. Brachycephalic airway obstructive syndrome. Probl Vet Med — PubMed:PMID1802247 — OMIA Phene_Article / Article
  • 2011. Canine brachycephalic airway syndrome: surgical management. Compend Contin Educ Vet — PubMed:PMID21870354 — OMIA Phene_Article / Article
  • 2011. Canine brachycephalic airway syndrome: pathophysiology, diagnosis, and nonsurgical management. Compend Contin Educ Vet — PubMed:PMID21870353 — OMIA Phene_Article / Article
  • 2012. Brachycephalic airway syndrome: pathophysiology and diagnosis. Compend Contin Educ Vet — PubMed:PMID22847322 — OMIA Phene_Article / Article
  • 2012. Brachycephalic airway syndrome: management. Compend Contin Educ Vet — PubMed:PMID22935992 — OMIA Phene_Article / Article
  • 2013. Management of acute respiratory distress syndrome in a French Bulldog using airway pressure release ventilation. J Vet Emerg Crit Care (San Antonio) — PubMed:PMID23855595 | DOI:10.1111/vec.12071 — OMIA Phene_Article / Article
  • 2013. Assessment of circulating concentrations of proinflammatory and anti-inflammatory cytokines and nitric oxide in dogs with brachycephalic airway obstruction syndrome. Am J Vet Res — PubMed:PMID23270361 | DOI:10.2460/ajvr.74.1.155 — OMIA Phene_Article / Article
  • 2012. Evaluation of C-reactive protein, haptoglobin and cardiac troponin 1 levels in brachycephalic dogs with upper airway obstructive syndrome. BMC Vet Res — PubMed:PMID22937913 | DOI:10.1186/1746-6148-8-152 — OMIA Phene_Article / Article
  • (86 additional references in OMIA)

Evidence (references)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

  • 1989. Inherited and congenital airway conditions in dogs and cats. Journal of Small Animal Practice — OMIA Phene_Article / Article
  • 1997. Brachycephalic airway obstruction syndrome - a review of 118 cases. Canine Practice — OMIA Phene_Article / Article
  • 2010. Brachycephalic airway obstructive syndrome in dogs: 90 cases (1991-2008). J Am Vet Med Assoc — PubMed:PMID21034343 | DOI:10.2460/javma.237.9.1048 — OMIA Phene_Article / Article
  • 1992. Brachycephalic airway syndrome. Vet Clin North Am Small Anim Pract — PubMed:PMID1523786 — OMIA Phene_Article / Article
  • 1991. Brachycephalic airway obstructive syndrome. Probl Vet Med — PubMed:PMID1802247 — OMIA Phene_Article / Article
  • 2011. Canine brachycephalic airway syndrome: surgical management. Compend Contin Educ Vet — PubMed:PMID21870354 — OMIA Phene_Article / Article
  • 2011. Canine brachycephalic airway syndrome: pathophysiology, diagnosis, and nonsurgical management. Compend Contin Educ Vet — PubMed:PMID21870353 — OMIA Phene_Article / Article
  • 2012. Brachycephalic airway syndrome: pathophysiology and diagnosis. Compend Contin Educ Vet — PubMed:PMID22847322 — OMIA Phene_Article / Article
  • 2012. Brachycephalic airway syndrome: management. Compend Contin Educ Vet — PubMed:PMID22935992 — OMIA Phene_Article / Article
  • 2013. Management of acute respiratory distress syndrome in a French Bulldog using airway pressure release ventilation. J Vet Emerg Crit Care (San Antonio) — PubMed:PMID23855595 | DOI:10.1111/vec.12071 — OMIA Phene_Article / Article
  • 2013. Assessment of circulating concentrations of proinflammatory and anti-inflammatory cytokines and nitric oxide in dogs with brachycephalic airway obstruction syndrome. Am J Vet Res — PubMed:PMID23270361 | DOI:10.2460/ajvr.74.1.155 — OMIA Phene_Article / Article
  • 2012. Evaluation of C-reactive protein, haptoglobin and cardiac troponin 1 levels in brachycephalic dogs with upper airway obstructive syndrome. BMC Vet Res — PubMed:PMID22937913 | DOI:10.1186/1746-6148-8-152 — OMIA Phene_Article / Article
  • (86 additional references in OMIA)

Sources

Dog (Canis lupus familiaris) — BOAS (hereditary; OMIA-verified species predisposition)
companion-species-healthPMID 21034343

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