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Dog (Canis lupus familiaris) — Aortic stenosis, subvalvular (hereditary; OMIA-verified species predisposition)

companion_species_health_aortic_stenosis_subvalvular_dog

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--- license: permission_granted topic_id: companion_species_health_aortic_stenosis_subvalvular_dog category: companion-species-health title: "Dog (Canis lupus familiaris) — Aortic stenosis, subvalvular (hereditary; OMIA-verified species predisposition)" lang: en source: "OMIA (Online Mendelian Inheritance in Animals, University of Sydney) species-specific hereditary-disorder record, saved verbatim to source_file; C1 substring-verified. Pulled 2026-08-24 from local OMIA database dump." source_file: pdf-raw/species-health/dog_aortic_stenosis_subvalvular_131.txt date_parsed: 2026-08-24 tokens_estimated: 201 verification: method: substring_match claims: 4 passed: 4 date: 2026-08-24 recovered: false path: companion-species-health/companion_species_health_aortic_stenosis_subvalvular_dog/01_companion_species_health_aortic_stenosis_subvalvular_dog.md source_document: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" citation: authority: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" title: "Dog (Canis lupus familiaris) — Aortic stenosis, subvalvular (hereditary; OMIA-verified species predisposition)" url: "https://omia.org/OMIA000052/9615/" retrieved: "2026-08-24" ref: "OMIA species-specific hereditary-disorder records (omia.org), derived from local OMIA database dump; dataset: https://doi.org/10.25910/2AMR-PV70" doc_type: "academic animal-genetics database (species-specific disorder entries)" needs_review: false

verification_derived: method: derived_from_dataset source: "OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM" note: "Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose." verification_derived: method: derived_from_dataset source: "OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM" note: "Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose."---

Dog (Canis lupus familiaris) — Aortic stenosis, subvalvular (hereditary; OMIA-verified species predisposition)

Source: first-hand OMIA (University of Sydney) species-specific hereditary-disorder record, saved verbatim to source_file; every claim below is a C1 byte-substring of it.

Claims

  • Species: Dog (Canis lupus familiaris)
  • Disorder: Aortic stenosis, subvalvular
  • Summary: "Subvalvular aortic stenosis (SAS) is one of the most common congenital heart defects of dogs ... that can result in fainting, a shortened life span, or sudden death. ... The disease is characterized by obstruction of the left ventricular outflow tract, resulting in pressure overload on the left ventricle. The etiology of obstruction is a fibromuscular nodule, ridge, or ring of tissue that increases aortic outflow tract velocity." (Ontiveros and Stern, 2021) See also OMIA:000952-9615 : Subaortic stenosis in Canis lupus familiaris
  • Prevalence: "The prevalence of this disease was reported at 4.7 % in a large veterinary referral hospital." (Ontiveros and Stern, 2021)

Evidence (references)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

  • 1989. Medical and Surgical Management of Aortic Stenosis in a Dog. Canadian Veterinary Journal-Revue Veterinaire Canadienne — OMIA Phene_Article / Article
  • 1989. Canine Congenital Aortic Stenosis - A Review of the Literature and Commentary. Canadian Veterinary Journal-Revue Veterinaire Canadienne — OMIA Phene_Article / Article
  • 1994. Clinical and Pathological Characterization of an Unusual Form of Subvalvular Aortic Stenosis in 4 Golden Retriever Puppies. Journal of the American Animal Hospital Association — OMIA Phene_Article / Article
  • 1995. Sedation and anesthesia in dogs and cats with cardiovascular disease. Schweizer Archiv Fur Tierheilkunde — PubMed:PMID7569846 — OMIA Phene_Article / Article
  • 1997. Open resection for subvalvular aortic stenosis in dogs (vol 209, pg 1255, 1996). Journal of the American Veterinary Medical Association — OMIA Phene_Article / Article
  • 1997. Retrospective study of congenital heart defects in 151 dogs. Journal of Small Animal Practice — PubMed:PMID9097239 — OMIA Phene_Article / Article
  • 1997. Surgical management of subvalvular aortic stenosis and mitral dysplasia in a golden retriever. Journal of Small Animal Practice — PubMed:PMID9200115 — OMIA Phene_Article / Article
  • 1998. Analysis ofmurmur intensity, duration and frequency components in dogs with aortic stenosis. Journal of Small Animal Practice — PubMed:PMID9693417 — OMIA Phene_Article / Article
  • 1998. Clinical and pathological findings of severe subvalvular aortic stenosis and mitral dysplasia in a rottweiler puppy. Journal of Small Animal Practice — PubMed:PMID9816571 — OMIA Phene_Article / Article
  • 2000. Prevalence of murmurs consistent with aortic stenosis among boxer dogs in Norway and Sweden. Veterinary Record — PubMed:PMID10975330 — OMIA Phene_Article / Article
  • 2000. Progression of aortic stenosis in the boxer. Journal of Small Animal Practice — PubMed:PMID11072913 — OMIA Phene_Article / Article
  • 2009. Congenital heart disease in boxer dogs: results of 6 years of breed screening. Vet J — PubMed:PMID18400530 | DOI:10.1016/j.tvjl.2008.02.008 — OMIA Phene_Article / Article
  • (17 additional references in OMIA)

Evidence (references)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

  • 1989. Medical and Surgical Management of Aortic Stenosis in a Dog. Canadian Veterinary Journal-Revue Veterinaire Canadienne — OMIA Phene_Article / Article
  • 1989. Canine Congenital Aortic Stenosis - A Review of the Literature and Commentary. Canadian Veterinary Journal-Revue Veterinaire Canadienne — OMIA Phene_Article / Article
  • 1994. Clinical and Pathological Characterization of an Unusual Form of Subvalvular Aortic Stenosis in 4 Golden Retriever Puppies. Journal of the American Animal Hospital Association — OMIA Phene_Article / Article
  • 1995. Sedation and anesthesia in dogs and cats with cardiovascular disease. Schweizer Archiv Fur Tierheilkunde — PubMed:PMID7569846 — OMIA Phene_Article / Article
  • 1997. Open resection for subvalvular aortic stenosis in dogs (vol 209, pg 1255, 1996). Journal of the American Veterinary Medical Association — OMIA Phene_Article / Article
  • 1997. Retrospective study of congenital heart defects in 151 dogs. Journal of Small Animal Practice — PubMed:PMID9097239 — OMIA Phene_Article / Article
  • 1997. Surgical management of subvalvular aortic stenosis and mitral dysplasia in a golden retriever. Journal of Small Animal Practice — PubMed:PMID9200115 — OMIA Phene_Article / Article
  • 1998. Analysis ofmurmur intensity, duration and frequency components in dogs with aortic stenosis. Journal of Small Animal Practice — PubMed:PMID9693417 — OMIA Phene_Article / Article
  • 1998. Clinical and pathological findings of severe subvalvular aortic stenosis and mitral dysplasia in a rottweiler puppy. Journal of Small Animal Practice — PubMed:PMID9816571 — OMIA Phene_Article / Article
  • 2000. Prevalence of murmurs consistent with aortic stenosis among boxer dogs in Norway and Sweden. Veterinary Record — PubMed:PMID10975330 — OMIA Phene_Article / Article
  • 2000. Progression of aortic stenosis in the boxer. Journal of Small Animal Practice — PubMed:PMID11072913 — OMIA Phene_Article / Article
  • 2009. Congenital heart disease in boxer dogs: results of 6 years of breed screening. Vet J — PubMed:PMID18400530 | DOI:10.1016/j.tvjl.2008.02.008 — OMIA Phene_Article / Article
  • (17 additional references in OMIA)

Sources

Dog (Canis lupus familiaris) — Aortic stenosis, subvalvular (hereditary; OMIA-verified species predisposition)
companion-species-healthPMID 7569846

Machine access

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