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Shih Tzu — Glaucoma, primary open angle (hereditary; OMIA-verified breed predisposition)

companion_breed_health_shih_tzu_omia3925_dog

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--- license: permission_granted topic_id: companion_breed_health_shih_tzu_omia3925_dog category: companion-breed-health title: "Shih Tzu — Glaucoma, primary open angle (hereditary; OMIA-verified breed predisposition)" lang: en source: "OMIA (Online Mendelian Inheritance in Animals, University of Sydney) breed-specific hereditary-disorder record, saved verbatim to source_file; C1 substring-verified. Pulled 2026-08-02 from local OMIA database dump." source_file: pdf-raw/breed-health/shih_tzu_omia3925_3925.txt date_parsed: 2026-08-02 tokens_estimated: 109 verification: method: substring_match claims: 4 passed: 4 date: 2026-08-02 recovered: false path: companion-breed-health/companion_breed_health_shih_tzu_omia3925_dog/01_companion_breed_health_shih_tzu_omia3925_dog.md source_document: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" citation: authority: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" title: "Shih Tzu — Glaucoma, primary open angle (hereditary; OMIA-verified breed predisposition)" url: "https://omia.org/OMIA002046/9615/" retrieved: "2026-08-02" ref: "OMIA breed-specific hereditary-disorder records (omia.org), derived from local OMIA database dump; dataset: https://doi.org/10.25910/2AMR-PV70" doc_type: "academic animal-genetics database (breed-specific disorder entries)" needs_review: false

Shih Tzu — Glaucoma, primary open angle (hereditary; OMIA-verified breed predisposition)

Source: first-hand OMIA (University of Sydney) breed-specific hereditary-disorder record, saved verbatim to source_file; every claim below is a C1 byte-substring of it.

Claims

  • Breed: Shih Tzu (Dog)
  • Disorder:
  • Summary: see also entries in OMIA relating to forms of this disease for which causal variants have been identified: e.g., OMIA:001870-9615 : Glaucoma, primary open angle, ADAMTS10-related in Canis lupus familiaris; OMIA:001976-9615 : Glaucoma, primary open angle, ADAMTS17-related in Canis lupus familiaris
  • Defect: yes

Evidence (references)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose.

  • 2013. Dogs and humans share a common susceptibility gene SRBD1 for glaucoma risk.. PLoS One — PubMed:PMID24040232 | DOI:10.1371/journal.pone.0074372 — OMIA Phene_Article / Article
  • 2017. Genetic and biochemical biomarkers in canine glaucoma.. Vet Pathol — PubMed:PMID27681326 | DOI:10.1177/0300985816666611 — OMIA Phene_Article / Article
  • 2019. Primary angle-closure glaucoma with goniodysgenesis in a Beagle dog.. BMC Vet Res — PubMed:PMID30832652 | DOI:10.1186/s12917-019-1812-1 — OMIA Phene_Article / Article
  • 2022. A genome-wide association study to investigate genetic loci associated with primary glaucoma in American Cocker Spaniels.. Am J Vet Res — PubMed:PMID36170212 | DOI:10.2460/ajvr.22.07.0106 — OMIA Phene_Article / Article
  • 2021. The Blue Book: Ocular disorders presumed to be inherited in purebred dogs. 13th Edition. https://ofa.org/wp-content/uploads/2022/10/ACVO-Blue-Book-2021.pdf — OMIA Phene_Article / Article

Evidence (references)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose.

  • 2013. Dogs and humans share a common susceptibility gene SRBD1 for glaucoma risk. PLoS One — PubMed:PMID24040232 | DOI:10.1371/journal.pone.0074372 — OMIA Phene_Article / Article
  • 2017. Genetic and biochemical biomarkers in canine glaucoma. Vet Pathol — PubMed:PMID27681326 | DOI:10.1177/0300985816666611 — OMIA Phene_Article / Article
  • 2019. Primary angle-closure glaucoma with goniodysgenesis in a Beagle dog. BMC Vet Res — PubMed:PMID30832652 | DOI:10.1186/s12917-019-1812-1 — OMIA Phene_Article / Article
  • 2022. A genome-wide association study to investigate genetic loci associated with primary glaucoma in American Cocker Spaniels. Am J Vet Res — PubMed:PMID36170212 | DOI:10.2460/ajvr.22.07.0106 — OMIA Phene_Article / Article
  • 2021. The Blue Book: Ocular disorders presumed to be inherited in purebred dogs. 13th Edition. https://ofa.org/wp-content/uploads/2022/10/ACVO-Blue-Book-2021.pdf — OMIA Phene_Article / Article

Evidence (references)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

  • 2013. Dogs and humans share a common susceptibility gene SRBD1 for glaucoma risk. PLoS One — PubMed:PMID24040232 | DOI:10.1371/journal.pone.0074372 — OMIA Phene_Article / Article
  • 2017. Genetic and biochemical biomarkers in canine glaucoma. Vet Pathol — PubMed:PMID27681326 | DOI:10.1177/0300985816666611 — OMIA Phene_Article / Article
  • 2019. Primary angle-closure glaucoma with goniodysgenesis in a Beagle dog. BMC Vet Res — PubMed:PMID30832652 | DOI:10.1186/s12917-019-1812-1 — OMIA Phene_Article / Article
  • 2022. A genome-wide association study to investigate genetic loci associated with primary glaucoma in American Cocker Spaniels. Am J Vet Res — PubMed:PMID36170212 | DOI:10.2460/ajvr.22.07.0106 — OMIA Phene_Article / Article
  • 2021. The Blue Book: Ocular disorders presumed to be inherited in purebred dogs. 13th Edition. https://ofa.org/wp-content/uploads/2022/10/ACVO-Blue-Book-2021.pdf — OMIA Phene_Article / Article

verification_derived: method: derived_from_dataset source: "OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM" note: "Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose."

Evidence (references)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

  • 2013. Dogs and humans share a common susceptibility gene SRBD1 for glaucoma risk. PLoS One — PubMed:PMID24040232 | DOI:10.1371/journal.pone.0074372 — OMIA Phene_Article / Article
  • 2017. Genetic and biochemical biomarkers in canine glaucoma. Vet Pathol — PubMed:PMID27681326 | DOI:10.1177/0300985816666611 — OMIA Phene_Article / Article
  • 2019. Primary angle-closure glaucoma with goniodysgenesis in a Beagle dog. BMC Vet Res — PubMed:PMID30832652 | DOI:10.1186/s12917-019-1812-1 — OMIA Phene_Article / Article
  • 2022. A genome-wide association study to investigate genetic loci associated with primary glaucoma in American Cocker Spaniels. Am J Vet Res — PubMed:PMID36170212 | DOI:10.2460/ajvr.22.07.0106 — OMIA Phene_Article / Article
  • 2021. The Blue Book: Ocular disorders presumed to be inherited in purebred dogs. 13th Edition. https://ofa.org/wp-content/uploads/2022/10/ACVO-Blue-Book-2021.pdf — OMIA Phene_Article / Article

verification_derived: method: derived_from_dataset source: "OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM" note: "Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose."

Evidence (references)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

  • 2013. Dogs and humans share a common susceptibility gene SRBD1 for glaucoma risk. PLoS One — PubMed:PMID24040232 | DOI:10.1371/journal.pone.0074372 — OMIA Phene_Article / Article
  • 2017. Genetic and biochemical biomarkers in canine glaucoma. Vet Pathol — PubMed:PMID27681326 | DOI:10.1177/0300985816666611 — OMIA Phene_Article / Article
  • 2019. Primary angle-closure glaucoma with goniodysgenesis in a Beagle dog. BMC Vet Res — PubMed:PMID30832652 | DOI:10.1186/s12917-019-1812-1 — OMIA Phene_Article / Article
  • 2022. A genome-wide association study to investigate genetic loci associated with primary glaucoma in American Cocker Spaniels. Am J Vet Res — PubMed:PMID36170212 | DOI:10.2460/ajvr.22.07.0106 — OMIA Phene_Article / Article
  • 2021. The Blue Book: Ocular disorders presumed to be inherited in purebred dogs. 13th Edition. https://ofa.org/wp-content/uploads/2022/10/ACVO-Blue-Book-2021.pdf — OMIA Phene_Article / Article

verification_derived: method: derived_from_dataset source: "OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM" note: "Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose."

Sources

Shih Tzu — Glaucoma, primary open angle (hereditary; OMIA-verified breed predisposition)
companion-breed-healthPMID 24040232

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